Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Connie L. Sivinski"'
Autor:
Michelle L. VanLith, Karl G. Kohlgraf, Michael A. Hollingsworth, Keita Morikane, Richard M. Tempero, Connie L. Sivinski
Publikováno v:
Cancer Immunology, Immunotherapy. 51:327-340
Previous studies have indicated that different effector cells are required to eliminate MUC1-expressing tumors derived from different organ sites and that different vaccine strategies may be necessary to generate these two different MUC1-specific imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b78ad28d69a12a7d299a8fa3f5b0bf
https://doi.org/10.1007/s00262-002-0277-3
https://doi.org/10.1007/s00262-002-0277-3
Autor:
Michelle L. VanLith, Karl G. Kohlgraf, Connie L. Sivinski, Michael A. Hollingsworth, Richard M. Tempero
Publikováno v:
International Immunology. 14:873-882
MUC1 was first defined as a tumor antigen in the late 1980s, yet little is known about the types of immune responses that mediate rejection of MUC1(+) tumors in vivo. MUC1-specific antibodies, T(h) cells and cytotoxic T cells can be detected in patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fdd4f7d6fa6849917e67965d72a2e3d
https://doi.org/10.1093/intimm/dxf053
https://doi.org/10.1093/intimm/dxf053
Autor:
Richard M. Tempero, Michael A. Hollingsworth, Shimichi Kitajima, Keita Morikane, Connie L. Sivinski, Sandra J. Gendler
Publikováno v:
International Immunology. 13:233-240
We investigated the influence of organ-specific parameters on tolerance and immunity to human MUC1. C57Bl/6 mice (wild-type) and C57Bl/6 transgenic for MUC1 (MUC1.Tg) were challenged in the pancreas with Panc02-MUC1, a C57Bl/6-syngeneic pancreatic ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600f45494494754c2154aba24a57a0d5
https://doi.org/10.1093/intimm/13.2.233
https://doi.org/10.1093/intimm/13.2.233
Autor:
Mitsuharu Nomoto, Michael A. Hollingsworth, Richard M. Tempero, Connie L. Sivinski, Tetsuichiro Muto, Keita Morikane, Michelle L. Van Lith
Publikováno v:
Cancer Immunology, Immunotherapy. 47:287-296
We established a model of orthotopic injection of a syngeneic pancreatic tumor cell line in C57BL/6 mice and evaluated the effects of organ site on induction of immunity to a tumor-specific antigen, MUC1. Mice were challenged with a syngeneic pancrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30615ec834787c7d10f52f5fa23cd45b
https://doi.org/10.1007/s002620050533
https://doi.org/10.1007/s002620050533
Publikováno v:
Journal of Immunotherapy. 18:156-165
Interferons (IFNs) are known to have antiviral effects and have been shown to enhance the expression of tumor-associated antigens (TAA) on different target cells. In our current study, we investigated the potential of IFN-alpha or IFN-gamma to enhanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1fc8d964564832a527040273bd6f6b
https://doi.org/10.1097/00002371-199510000-00003
https://doi.org/10.1097/00002371-199510000-00003
Autor:
Connie L. Sivinski, Margaret A. Tempero, Yoshio Haga, Zenon Steplewski, Parviz M. Pour, H. D. Kay
Publikováno v:
International journal of pancreatology. 9:125-134
Conventional therapy of pancreatic exocrine cancer is disappointing. The poor prognosis of the disease challenges development of novel therapeutic strategies. We report the results of clinical trials of the monoclonal antibody (Mab) 17-1A in patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402b559a723036a249a1cc73f217f387
https://doi.org/10.1007/bf02925588
https://doi.org/10.1007/bf02925588
Publikováno v:
Autoimmune Reactions ISBN: 9781461272151
The purpose of this chapter is to describe inflammatory and autoimmune reactions that are secondary to the development of cancer. In some cases, it is believed that inflammatory and autoimmune reactions result from interactions between substances and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d2a8e62fa524275c858712fd6d92a28
https://doi.org/10.1007/978-1-4612-1610-0_22
https://doi.org/10.1007/978-1-4612-1610-0_22
Publikováno v:
International journal of pancreatology. 15
Chimeric 17-1A antibody (IgG1 kappa) was constructed by linking variable region genes of murine monoclonal antibody 17-1A with genes for human kappa light chain and gamma 1 heavy-chain constant regions. This study was undertaken to compare in vitro a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c1f21146012d776bb4aa61ad9748d4
https://doi.org/10.1007/bf02924387
https://doi.org/10.1007/bf02924387
Autor:
Lynell Warren Klassen, Connie L. Sivinski, Yoshio Haga, Margaret A. Tempero, Diane F. Birt, Geoffrey M. Thiele
Publikováno v:
Scopus-Elsevier
Selected immunomodulatory effects of levamisole were studied in patients with asymptomatic metastatic colon cancer and in a preclinical model (CF 1 female mice treated with methyl-azoxymethanol acetate) for colon tumors. In the patient population stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b406f13645587bc60e1348cdc24bef
http://www.scopus.com/inward/record.url?eid=2-s2.0-0028985214&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0028985214&partnerID=MN8TOARS