Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Connie A. Cummings"'
Autor:
Suramya Waidyanatha, Shyamal D. Peddada, Mamta Behl, Arun R. Pandiri, Yu Wang, Deloris Sutton, Connie A. Cummings, Kevin Gerrish, F Foley Julie, Keith R. Shockley, Mark J. Hoenerhoff, Haruhiro Yamashita, Robert C. Sills
Publikováno v:
Toxicologic Pathology. 46:564-573
There was a significant increase in the incidence of retinal degeneration in F344/N rats chronically exposed to Kava kava extract (KKE) in National Toxicology Program (NTP) bioassay. A retrospective evaluation of these rat retinas indicated a similar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de66da109b36456f4473b3ac593d03d
https://doi.org/10.1177/0192623318778796
https://doi.org/10.1177/0192623318778796
Autor:
Xiaohua Gao, Darlene Dixon, Deloris Sutton, Linda Yu, Yitang Yan, Lysandra Castro, Alicia B. Moore, Connie A. Cummings
Publikováno v:
Genes, Chromosomes and Cancer. 55:397-406
Histone phosphorylation has a profound impact on epigenetic regulation of gene expression, chromosome condensation and segregation, and maintenance of genome integrity. Histone H3 Serine 10 is evolutionally conserved and heavily phosphorylated during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::635822a717f806f3bfc2b72358286ced
https://doi.org/10.1002/gcc.22343
https://doi.org/10.1002/gcc.22343
Autor:
Eugenia H. Goulding, James W. Putney, Edward M. Eddy, Gary S. Bird, Kyathanahalli S. Janardhan, Felicity M. Davis, Connie A. Cummings, Diane M. D’Agostin
Publikováno v:
Cell calcium. 59(4)
Store-operated calcium entry (SOCE) is an important Ca(2+) influx pathway in somatic cells. In addition to maintaining endoplasmic reticulum (ER) Ca(2+) stores, Ca(2+) entry through store-operated channels regulates essential signaling pathways in nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9fbfb236f9e3724b3a8c38729d6a806
https://pubmed.ncbi.nlm.nih.gov/26969191
https://pubmed.ncbi.nlm.nih.gov/26969191
Autor:
Connie A. Cummings, James Greg Falls, Nancy R. Bordelon, Richard A. Peterson, Thomas A. Brodie, Elizabeth H. Romach, Richard T. Miller, Brenda Faiola
Publikováno v:
Toxicological Sciences. 105:384-394
Therapeutic use of certain peroxisome proliferator-activated receptor (PPAR) alpha agonists (fibrates) for the treatment of dyslipidemia has infrequently been associated with the untoward side effect of myopathy. With interest in PPAR-delta as a ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7b85eb0c631b90496aab94b750cf89
https://doi.org/10.1093/toxsci/kfn130
https://doi.org/10.1093/toxsci/kfn130
Autor:
Opher Gileadi, Nathan Ezov, Abraham Nyska, Yona Grunfeld, Vered Behar, Connie A. Cummings, Jonathan Nadler, Anya Vainshtein
Publikováno v:
Toxicologic Pathology. 32:357-363
In this report we introduce wet-tissue scanning electron microscopy, a novel technique for direct imaging of wet tissue samples using backscattered electrons. Samples placed in sealed capsules are imaged through a resilient, electron-transparent memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e158132f4a2eabb3067cc878872fa9
https://doi.org/10.1080/01926230490431772
https://doi.org/10.1080/01926230490431772
Autor:
Abraham Nyska, David G. Allen, Connie A. Cummings, Shyamal D. Peddada, Carolyn F. Moyer, Cindy R. Moomaw, Po C. Chan, Julie F. Foley, David E. Malarkey, Robert R. Maronpot, Greg Travlos
Publikováno v:
Toxicology and Applied Pharmacology. 184:153-164
Riddelliineis a naturally occurring pyrrolizidine alkaloid found in certain poisonous rangeland plants of the western United States. In National Toxicology Program 2-year studies, riddelliine induced high incidences of hemangiosarcoma in the liver of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ccc863f8e449db6d9c04206174bd768
https://doi.org/10.1006/taap.2002.9485
https://doi.org/10.1006/taap.2002.9485
Autor:
Suzanne E. Fenton, Adam J. Filgo, Connie A. Cummings, Erin M. Quist, Grace E. Kissling, Mark J. Hoenerhoff
Perfluorooctanoic acid (PFOA) is a perfluoroalkyl acid primarily used as an industrial surfactant. It persists in the environment and has been linked to potentially toxic and/or carcinogenic effects in animals and people. As a known activator of pero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08f7f2abca004c8eb321c41475b692dd
https://europepmc.org/articles/PMC4400180/
https://europepmc.org/articles/PMC4400180/
Autor:
Patrick A Cosgrove, William G. Richards, Chi Ming Li, George A. Carlson, Connie A. Cummings, Mark Chhoa, Tibor Gyuris, Todd Juan, Will Baron, James R. Turk, Murielle M. Véniant, Jim Busby, David Lloyd, Stephen Kaufman, Jeff Lawrence, Ki Won Kim, Joan Helmering
Publikováno v:
Lipids in Health and Disease
Background Previously, we identified three loci affecting HDL-cholesterol levels in a screen for ENU-induced mutations in mice and discovered two mutated genes. We sought to identify the third mutated gene and further characterize the mouse phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34baa070e36dbf1e0b3a115a6dc5f3e6
http://europepmc.org/articles/PMC4232700
http://europepmc.org/articles/PMC4232700
Autor:
Susan A. Elmore, David E. Malarkey, Elizabeth F. McInnes, Cynthia Shackelford, Torrie A. Crabbs, Jerrold M. Ward, Michael C. Boyle, Crystal L. Johnson, Connie A. Cummings, Thomas Nolte, Molly H. Boyle, Margarita M. Gruebbel, Michelle C. Cora
The 2013 annual National Toxicology Program (NTP) Satellite Symposium, entitled “Pathology Potpourri,” was held in Portland, Oregon, in advance of the Society of Toxicologic Pathology’s 32nd annual meeting. The goal of the NTP Symposium is to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e86e7ea8eea50761967a6f119f2faa12
https://europepmc.org/articles/PMC3992853/
https://europepmc.org/articles/PMC3992853/
Publikováno v:
Biology of Reproduction. 88
Sertoli cells provide nutritional and physical support to germ cells during spermatogenesis. Sox8 encodes a member of the high mobility group of transcription factors closely related to Sox9 and Sox10. Sertoli cells express SOX8 protein, and its elim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fc02f4e8fccf7ccb903b0285e2209da
https://doi.org/10.1095/biolreprod.112.107284
https://doi.org/10.1095/biolreprod.112.107284