Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Connexins/*genetics/metabolism"'
Publikováno v:
Nature Communications, Vol. 12, No 1 (2021) P. 4484
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Reactive oxygen species (ROS) represent a by-product of metabolism and their excess is toxic for hematopoietic stem and progenitor cells (HSPCs). During embryogenesis, a small number of HSPCs are produced from the hemogenic endothelium, before they c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::57a5d4ac49f1ad6010e6ef32b8f9e16b
https://archive-ouverte.unige.ch/unige:154572
https://archive-ouverte.unige.ch/unige:154572
Publikováno v:
Frontiers in Immunology, Vol. 7, No 7 (2016) P. 684
Frontiers in Immunology
Frontiers in Immunology
Lymph node stromal cells (LNSCs) have newly been promoted to the rank of new modulators of T cell responses. The different non-hematopoietic cell subsets in lymph node (LN) were considered for years as a simple scaffold, forming routes and proper env
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c505d82e8f1cf8c68c908a5517f365e8
Autor:
Jun Yin, Marc Chanson, Wolfgang M. Kuebler, Julia Hoffmann, Hermann Kuppe, Brenda R. Kwak, Hannah T. Nickles, Eduardo Barbosa-Sicard, Martin Witzenrath, Liming Wang, Hee-Sup Shin, Arata Tabuchi, Songwei Wu, Brant E. Isakson, Hannes Ranke, Christoph Tabeling, Cor de Wit, Ingrid Fleming
Publikováno v:
Journal of Clinical Investigation, Vol. 122, No 11 (2012) pp. 4218-30
The Journal of clinical investigation
The Journal of clinical investigation
Hypoxic pulmonary vasoconstriction (HPV) is a physiological mechanism by which pulmonary arteries constrict in hypoxic lung areas in order to redirect blood flow to areas with greater oxygen supply. Both oxygen sensing and the contractile response ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52931087d4b5cb6aeb94c5c6f7465746
https://doi.org/10.1172/jci59176
https://doi.org/10.1172/jci59176
Autor:
Esther Sutter, Anna Pfenniger, Sylvie Dunoyer-Geindre, Brenda R. Kwak, François Mach, Paul C. Evans, Simon Cuhlmann, Rob Krams, Anton J.G. Horrevoets, Cindy W Wong
Publikováno v:
Journal of molecular and cellular cardiology
Journal of Molecular and Cellular Cardiology, Vol. 53, No 2 (2012) pp. 299-309
Pfenniger, A, Wong, C, Sutter, E, Cuhlmann, S, Dunoyer-Geindre, S, Mach, F, Horrevoets, A J G, Evans, P C, Krams, R & Kwak, B R 2012, ' Shear stress modulates the expression of the atheroprotective protein Cx37 in endothelial cells ', Journal of Molecular and Cellular Cardiology, vol. 53, no. 2, pp. 299-309 . https://doi.org/10.1016/j.yjmcc.2012.05.011
Journal of Molecular and Cellular Cardiology, 53(2), 299-309. Academic Press Inc.
Journal of Molecular and Cellular Cardiology, Vol. 53, No 2 (2012) pp. 299-309
Pfenniger, A, Wong, C, Sutter, E, Cuhlmann, S, Dunoyer-Geindre, S, Mach, F, Horrevoets, A J G, Evans, P C, Krams, R & Kwak, B R 2012, ' Shear stress modulates the expression of the atheroprotective protein Cx37 in endothelial cells ', Journal of Molecular and Cellular Cardiology, vol. 53, no. 2, pp. 299-309 . https://doi.org/10.1016/j.yjmcc.2012.05.011
Journal of Molecular and Cellular Cardiology, 53(2), 299-309. Academic Press Inc.
High laminar shear stress (HLSS) is vasculoprotective partly through induction of Kruppel-like factor 2 (KLF2). Connexin37 (Cx37) is highly expressed in endothelial cells (ECs) of healthy arteries, but not in ECs overlying atherosclerotic lesions. Mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a4c322e1181da5ac05815067a954cd
https://doi.org/10.1016/j.yjmcc.2012.05.011
https://doi.org/10.1016/j.yjmcc.2012.05.011
Autor:
Muriel Jaquet, Naoyuki Miura, Amélie Sabine, Damien Bebber, René Hägerling, Yan Agalarov, Anna Pfenniger, Tatiana V. Petrova, Brenda R. Kwak, Taija Makinen, Hélène Maby-El Hajjami, Ralf H. Adams, Cathrin Pollmann, Olivier Dormond, Friedemann Kiefer, J. M. Calmes
Publikováno v:
Developmental cell
Developmental Cell, Vol. 22, No 2 (2012) pp. 430-45
Developmental Cell, Vol. 22, No 2 (2012) pp. 430-45
SummaryLymphatic valves are essential for efficient lymphatic transport, but the mechanisms of early lymphatic-valve morphogenesis and the role of biomechanical forces are not well understood. We found that the transcription factors PROX1 and FOXC2,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159eeb70fd8a5c2630609591bb8e273b
Autor:
Paolo Meda, Anne Charollais, Philippe Klee, Dorothée Caille, Jacques-Antoine Haefliger, Smaragda Lamprianou, Rossella Sarro, Manon Cederroth
Publikováno v:
Pediatric Research; Vol 70
Pediatric Research, Vol. 70, No 2 (2011) pp. 142-7
Pediatric research
Pediatric Research
Pediatric Research, Vol. 70, No 2 (2011) pp. 142-7
Pediatric research
Pediatric Research
Diabetes develops when the insulin needs of peripheral cells exceed the availability or action of the hormone. This situation results from the death of most beta-cells in type 1 diabetes, and from an inability of the beta-cell mass to adapt to increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eec4cf7b3163d97ce59a4e621342825
https://doi.org/10.1203/pdr.0b013e318220f106
https://doi.org/10.1203/pdr.0b013e318220f106
Autor:
A. Formenton, Thomas Tawadros, Paolo Meda, Pierre Tissières, Jacques-Antoine Haefliger, Pascal Nicod, Jean-Louis Bény, Peter Frey
Publikováno v:
Experimental Cell Research, Vol. 274, No 2 (2002) pp. 216-25
To evaluate the regulation of connexin expression by fluid pressure, we have studied the effects of elevated transmural urine pressure on Connexin43 (Cx43) and Cx26. We chose to focus on these two proteins out of the five connexins (Cx26, 43, 40, 37,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1e9db358980afdd9194e15f6889e4c
https://doi.org/10.1006/excr.2001.5465
https://doi.org/10.1006/excr.2001.5465
Publikováno v:
FEBS Letters, Vol. 588, No 8 (2014) pp. 1271-7
Connexins are transmembrane proteins that form gap junction- and hemi-channels. Once inserted into the membrane, hemi-channels (connexons) allow for diffusion of ions and small molecules (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1400::ef07ca6da86183cf959f9f3aff08a726
https://archive-ouverte.unige.ch/unige:38570
https://archive-ouverte.unige.ch/unige:38570
Publikováno v:
Swiss Medical Weekly, Vol. 142 (2012) P. w13553
Atherosclerosis, a progressive disease of medium- and large-sized arteries, constitutes the major cause of death in developed countries, and is becoming increasingly prevalent in developing countries as well. The main consequences of atherosclerosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1400::93bc7a1ad0cc5a4b4acaf54f00f0b7a4
https://archive-ouverte.unige.ch/unige:26725
https://archive-ouverte.unige.ch/unige:26725
Autor:
Benoit R. Gauthier, Laurence Zulianello, Eric Charpantier, Thierry Berney, Paolo Meda, Dorothée Caille, Piero Marchetti, Ben N G Giepmans, Anne Charollais, Vincenzo Cirulli, Véronique Serre-Beinier, Giuseppe R. Diaferia, Shaoping Deng, Domenico Bosco, Leo Buhler, Roberto Lupi
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Human molecular genetics, Vol. 18, No 3 (2009) pp. 428-39
Human Molecular Genetics
Human Molecular Genetics; Vol 18
Human Molecular Genetics, 18(3), 428-439. Oxford University Press
instname
Human molecular genetics, Vol. 18, No 3 (2009) pp. 428-39
Human Molecular Genetics
Human Molecular Genetics; Vol 18
Human Molecular Genetics, 18(3), 428-439. Oxford University Press
Previous studies have documented that the insulin-producing beta-cells of laboratory rodents are coupled by gap junction channels made solely of the connexin36 (Cx36) protein, and have shown that loss of this protein desynchronizes beta-cells, leadin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f5c1c19c3bdd8966ff8381f2bc08ff
http://hdl.handle.net/10261/270659
http://hdl.handle.net/10261/270659