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of 4
pro vyhledávání: '"Conner L. Olson"'
Autor:
Conner L. Olson, Deborah S. Wuttke
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 263 (2024)
Telomeres act as the protective caps of eukaryotic linear chromosomes; thus, proper telomere maintenance is crucial for genome stability. Successful telomere replication is a cornerstone of telomere length regulation, but this process can be fraught
Externí odkaz:
https://doaj.org/article/96edfbc23449414185031698b2f5de15
Publikováno v:
Nature Structural & Molecular Biology. 29:730-733
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f37de5fb702f1dc4fed9e2b87529f2f4
https://doi.org/10.1038/s41594-022-00818-3
https://doi.org/10.1038/s41594-022-00818-3
Publikováno v:
Nucleic Acids Research.
G-quadruplexes (G4s) are a set of stable secondary structures that form within guanine-rich regions of single-stranded nucleic acids that pose challenges for DNA maintenance. The G-rich DNA sequence at telomeres has a propensity to form G4s of variou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cc89547f203dc11b22b79c855b6c7ac
https://doi.org/10.1093/nar/gkad315
https://doi.org/10.1093/nar/gkad315
Autor:
Conner L. Olson, Ci Ji Lim, Arthur J. Zaug, Karen J. Goodrich, Deborah S. Wuttke, Thomas R. Cech, Maria T. Carilli
Publikováno v:
Nucleic Acids Research
The CST complex (CTC1-STN1-TEN1) has been shown to inhibit telomerase extension of the G-strand of telomeres and facilitate the switch to C-strand synthesis by DNA polymerase alpha-primase (pol α-primase). Recently the structure of human CST was sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b8a1bd6dff0602c46f867ae26afea4
https://pubmed.ncbi.nlm.nih.gov/34718732
https://pubmed.ncbi.nlm.nih.gov/34718732