Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Congren Wang"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract SPRED3 (Sprouty-related EVH1 domain containing 3) mutants are depicted in various cancers, however, nothing is known about its biofunction in thyroid cancer (THCA). Bioinformatic analyses were conducted to ascertain the level of SPRED3 expre
Externí odkaz:
https://doaj.org/article/e01e59ae9be9447eaf534d01a8b1706b
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-5 (2024)
Abstract The Neurotrophic tyrosine receptor kinase (NTRK) family plays important roles in tumor progression and is involved in tumor immunogenicity. Here, we conducted a comprehensive bioinformatic and clinical analysis to investigate the characteris
Externí odkaz:
https://doaj.org/article/a3c9998f83d7480e80f8a80f4d4025f1
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: The carcinogenesis and prognosis of hepatocellular carcinoma (HCC) involve complex molecular mechanisms, and ferroptosis is related to the development and therapeutic efficacy of HCC, but the specific mechanism and prognostic role of ferr
Externí odkaz:
https://doaj.org/article/464fe03af50548809a335a157b94b7e3
Publikováno v:
Tropical Journal of Pharmaceutical Research. Jan2024, Vol. 23 Issue 1, p15-25. 11p.
Publikováno v:
Molecular Biotechnology.
NKD inhibitor of WNT signaling pathway 2 (NKD2) is an emerging player in cancer onset and progression. Here, it was confirmed that THCA patients have robustly expressed NKD2, which was linked to an advanced pathologic stage. The prognosis was worse f
Publikováno v:
Annals of translational medicine. 10(18)
Circular RNAs (circRNAs) are a newly described class of non-coding RNAs that play essential roles in regulating gene expression. However, to date, few studies have examined the roles of circRNAs in papillary thyroid carcinoma (PTC). In this study, we
Autor:
Jiangman Zhao, Shouxin Wu, Huiqiang Li, Mingzhu Li, Zi-Jian Su, Congren Wang, Qunxiong Pan, Jian-Hua Zhang
Publikováno v:
Experimental and Therapeutic Medicine
A total of 15–30% of thyroid nodules that are evaluated by fine-needle aspiration are not clearly determined to be benign or malignant. Gene mutation analysis is recommended for the evaluation of thyroid nodules using clinical guidelines. The detec
Publikováno v:
Molecular genetics and genomics : MGG. 295(1)
Accumulating evidence has shown that the long noncoding RNAs (lncRNAs) play a crucial role in the regulation of hepatocellular carcinoma (HCC) progression and drug resistance. In this study, we aimed to investigate the biological function roles of ln
Publikováno v:
Oncotarget
MicroRNA (miRNA)-25 is a small non-coding RNA that has been implicated in the tumorigenesis of many cancers, but little is known on the role of miR-25 in HCC metastasis. We hereby found that miR-25 was significantly upregulated in clinical HCC tissue
Publikováno v:
Oncology reports. 34(4)
Mammalian target of rapamycin (mTOR) is frequently upregulated in hepatocellular carcinoma (HCC). Blockage of mTOR was found to induce marked reduction in HCC growth in preclinical models. In the present study, we tested a novel mTOR inhibitor, Torin