Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Conglei Li"'
Autor:
Hang Li, Tingting Zhang, Yingying Liao, Chutong Liu, Yisheng He, Yongfei Wang, Conglei Li, Cheng Jiang, Chenzhong Li, Guanghong Luo, Zhongyuan Xiang, Yanhong Duo
Publikováno v:
Aggregate, Vol 5, Iss 2, Pp n/a-n/a (2024)
Abstract The surface organs mainly comprise the superficial layers of various parts of the mammalian body, including the skin, eyes, and ears, which provide solid protection against various threats to the entire body. Damage to surface organs could l
Externí odkaz:
https://doaj.org/article/780dcf9800fd48b1b9ad362d4f785f49
Autor:
Yuehong Zhao, Qi Zhang, Botian Zhang, Yihao Dai, Yifei Gao, Chenzhong Li, Yijing Yu, Conglei Li
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8160 (2024)
Epstein–Barr virus (EBV), a member of the γ-herpesvirus family, is one of the most prevalent and persistent human viruses, infecting up to 90% of the adult population globally. EBV’s life cycle includes primary infection, latency, and lytic reac
Externí odkaz:
https://doaj.org/article/37fe650987964301b5ded4a0fab5144b
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14133 (2023)
The SARS-CoV-2 virus, causing the devastating COVID-19 pandemic, has been reported to affect platelets and cause increased thrombotic events, hinting at the possible bidirectional interactions between platelets and the virus. In this review, we discu
Externí odkaz:
https://doaj.org/article/e3b6924c213f4a34b0cab06aaba82426
Publikováno v:
Journal of Functional Biomaterials, Vol 13, Iss 4, p 220 (2022)
Here, we developed a new synthetic method for the production of a new class of polymeric inorganic hybrid biomaterial that has potential for dental implant applications and, in general, other orthopedic applications owing to its excellent mechanical
Externí odkaz:
https://doaj.org/article/60e008c6dc344c95921dd2868bc372b7
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Platelets, small anucleate cells circulating in the blood, are critical mediators in haemostasis and thrombosis. Interestingly, recent studies demonstrated that platelets contain both pro-inflammatory and anti-inflammatory molecules, equipping platel
Externí odkaz:
https://doaj.org/article/bfe89d25e9114dfaa5c9af19fd40948e
Autor:
Conglei Li, Thergiory Irrazabal, Clare C. So, Maribel Berru, Likun Du, Evelyn Lam, Alexanda K. Ling, Jennifer L. Gommerman, Qiang Pan-Hammarström, Alberto Martin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Class switch recombination (CSR) requires break and repair of immunoglobulin DNA. Here the authors show that the histone deubiquitinase Usp22 is involved in V(D)J recombination and CSR of IgG and IgE, but not IgA, and that IgG CSR is dependent on the
Externí odkaz:
https://doaj.org/article/905ec0c6076f4a6599d3753a0f2a55ca
Autor:
Shaliny Ramachandran, Dania Haddad, Conglei Li, Michael X. Le, Alexanda K. Ling, Clare C. So, Rajeev M. Nepal, Jennifer L. Gommerman, Kefei Yu, Troy Ketela, Jason Moffat, Alberto Martin
Publikováno v:
Cell Reports, Vol 15, Iss 7, Pp 1554-1565 (2016)
Summary: Class switch recombination (CSR) requires activation-induced deaminase (AID) to instigate double-stranded DNA breaks at the immunoglobulin locus. DNA breaks activate the DNA damage response (DDR) by inducing phosphorylation of histone H2AX f
Externí odkaz:
https://doaj.org/article/70f0a156b6574a9b8ddf6aae285ebf82
Autor:
Conglei Li, June Li, Yan Li, Sean Lang, Issaka Yougbare, Guangheng Zhu, Pingguo Chen, Heyu Ni
Publikováno v:
Advances in Hematology, Vol 2012 (2012)
Platelets are small anucleate cells circulating in the blood. It has been recognized for more than 100 years that platelet adhesion and aggregation at the site of vascular injury are critical events in hemostasis and thrombosis; however, recent studi
Externí odkaz:
https://doaj.org/article/ae328c71a1ea46d7ba525674218bd7fb
Autor:
Yan Yang, Zhenyin Shi, Adili Reheman, Joseph W Jin, Conglei Li, Yiming Wang, Marc C Andrews, Pingguo Chen, Guangheng Zhu, Wenhua Ling, Heyu Ni
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37323 (2012)
Delphinidin-3-glucoside (Dp-3-g) is one of the predominant bioactive compounds of anthocyanins in many plant foods. Although several anthocyanin compounds have been reported to be protective against cardiovascular diseases (CVDs), the direct effect o
Externí odkaz:
https://doaj.org/article/f38cfe4d7656481cb521bc993395fd98
Autor:
Jessica A. Stewart, Javier M. Di Noia, Amy Hin Yan Tong, Diana Nakib, Maribel Berru, Alberto Martin, Katherine Chan, Noé Seija Desivo, Gholam Ali Kardar, James R. Carlyle, Daniel Durocher, Rukshana Mohamad-Ramshan, Yuqing Feng, Jason Moffat, Madusha L. W. Perera, Rossanna C. Pezo, Alejandro Álvarez-Quilón, Philip Barbulescu, Ashok S. Bhagwat, Gavin Li, Conglei Li
Publikováno v:
Nature
Activation-induced cytidine deaminase (AID) catalyses the deamination of deoxycytidines to deoxyuracils within immunoglobulin genes to induce somatic hypermutation and class-switch recombination1,2. AID-generated deoxyuracils are recognized and proce