Zobrazeno 1 - 10
of 336
pro vyhledávání: '"Congenic mice"'
Publikováno v:
BMC Genetics, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background A genome-wide mapping study using male F2 zinc transporter 7-knockout mice (znt7-KO) and their wild type littermates in a mixed 129P1/ReJ (129P1) and C57BL/6J (B6) background identified a quantitative trait locus (QTL) on chromoso
Externí odkaz:
https://doaj.org/article/583f4cf4595542af9e84b8109207b8d7
Autor:
Osamu Ichii, Masataka Chihara, Shin-Hyo Lee, Teppei Nakamura, Saori Otsuka-Kanazawa, Taro Horino, Yaser Hosny Ali Elewa, Yasuhiro Kon
Publikováno v:
Autoimmunity, Vol 50, Iss 2, Pp 114-124 (2017)
Inbred MRL/MpJ mice show several unique phenotypes in tissue regeneration processes and the urogenital and immune systems. Clarifying the genetic and molecular bases of these phenotypes requires the analysis of their genetic susceptibility locus. Her
Externí odkaz:
https://doaj.org/article/aa9702b627f44577900dfd21ad0b0480
Akademický článek
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Autor:
Francisca F. Almeida, Sara Tognarelli, Antoine Marçais, Andrew J. Kueh, Miriam E. Friede, Yang Liao, Simon N. Willis, Kylie Luong, Fabrice Faure, Francois E. Mercier, Justine Galluso, Matthew Firth, Emilie Narni-Mancinelli, Bushra Rais, David T. Scadden, Francesco Spallotta, Sandra Weil, Ariane Giannattasio, Franziska Kalensee, Tobias Zöller, Nicholas D. Huntington, Ulrike Schleicher, Andreas G. Chiocchetti, Sophie Ugolini, Marco J. Herold, Wei Shi, Joachim Koch, Alexander Steinle, Eric Vivier, Thierry Walzer, Gabrielle T. Belz, Evelyn Ullrich
Publikováno v:
OncoImmunology, Vol 7, Iss 10 (2018)
NKp46 (CD335) is a surface receptor shared by both human and mouse natural killer (NK) cells and innate lymphoid cells (ILCs) that transduces activating signals necessary to eliminate virus-infected cells and tumors. Here, we describe a spontaneous p
Externí odkaz:
https://doaj.org/article/8e7af400c12d41358fe2c4876853dbc4
Autor:
Jonathan Ferrand, Nathan P. Croft, Geneviève Pépin, Kerrilyn R. Diener, Di Wu, Niamh E. Mangan, John Pedersen, Mark A. Behlke, John D. Hayball, Anthony W. Purcell, Richard L. Ferrero, Michael P. Gantier
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Murine models of Salmonella enterica serovar Typhimurium infection are one of the commonest tools to study host-pathogen interactions during bacterial infections. Critically, the outcome of S. Typhimurium infection is impacted by the genetic backgrou
Externí odkaz:
https://doaj.org/article/7e5861957058486b9b9cb60d528b59f8
Akademický článek
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Autor:
Paul Laissue, Besma Lakhal, Magalie Vatin, Frank Batista, Gaëtan Burgio, Eric Mercier, Esther Dos Santos, Christophe Buffat, Diana Carolina Sierra-Diaz, Gilles Renault, Xavier Montagutelli, Jane Salmon, Philippe Monget, Reiner A. Veitia, Céline Méhats, Marc Fellous, Jean-Christophe Gris, Julie Cocquet, Daniel Vaiman
Publikováno v:
Open Biology, Vol 6, Iss 10 (2016)
Recurrent spontaneous abortion (RSA) is a common cause of infertility, but previous attempts at identifying RSA causative genes have been relatively unsuccessful. Such failure to describe RSA aetiological genes might be explained by the fact that rep
Externí odkaz:
https://doaj.org/article/59cbc1af7cea42bd92495a8e90fb08ff
Publikováno v:
BioTechniques, Vol 52, Iss 3, Pp 183-190 (2012)
Congenic mapping is a powerful strategy to identify genomic loci regulating quantitative traits. Generating congenic lines is an iterative process of refinement that is both time and resource intensive. Here we report an alternative to traditional mi
Externí odkaz:
https://doaj.org/article/44c737e1ead84f9a86ed7cdc4b120e03
Autor:
Stanic, Aleksandar K., Stein, Charles M., Morgan, Adam C., Fazio, Sergio, Linton, MacRae F., Wakeland, Edward K., Olsen, Nancy J., Major, Amy S.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2006 May 01. 103(18), 7018-7023.
Externí odkaz:
https://www.jstor.org/stable/30052325
Autor:
Corina J.A. Moen, Aart P. Tholens, Peter J. Voshol, Willeke de Haan, Louis M. Havekes, Peter Gargalovic, Aldons J. Lusis, Ko Willems van Dȳk, Rune R. Frants, Marten H. Hofker, Patrick C.N. Rensen
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 10, Pp 2182-2192 (2007)
The Hyplip2 congenic mouse strain contains part of chromosome 15 from MRL/MpJ on the BALB/cJ background. Hyplip2 mice show increased plasma levels of cholesterol and predominantly triglycerides (TGs) and are susceptible to diet-induced atherosclerosi
Externí odkaz:
https://doaj.org/article/0b85f06617064831b97c73353612aa91