Zobrazeno 1 - 10
of 214
pro vyhledávání: '"CongCong Chen"'
Autor:
Bo Chen, Min Wang, Zongping Chen, Ningrui Pan, Xu He, Bengen Li, Congcong Chen, Zidong Zhou, Wei Cui, Peng Zhang, Qixu Ren, Youzhuang Zhong
Publikováno v:
BMC Urology, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background At present, the guidelines for urology recommend percutaneous nephrolithotomy (PCNL) as the preferred treatment for staghorn renal calculi (SRC). However, for complete SRC, it has been questioned by clinicians and patients due to
Externí odkaz:
https://doaj.org/article/1718b0e4fe2d42aa8f5cbcd02c5d661c
Autor:
Xuexia Xie, Congcong Chen, Cong Wang, Yongjian Guo, Binghe Sun, Jiaxin Tian, Jin Yan, Dake Li, Guo Chen
Publikováno v:
Redox Biology, Vol 76, Iss , Pp 103350- (2024)
BRCA1 is one of the most frequently-mutated tumor suppressor genes in ovarian and breast cancers. Loss of BRCA1 triggers homologous recombination (HR) repair deficiency, consequently leading to genomic instability and PARP inhibitors (PARPi)-associat
Externí odkaz:
https://doaj.org/article/5b950086f4bd4cd0a3f37646ba18474b
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Extracellular vesicles (EVs), characterized by low immunogenicity, high biocompatibility and targeting specificity along with excellent blood-brain barrier permeability, are increasingly recognized as promising drug delivery vehicles for treating a v
Externí odkaz:
https://doaj.org/article/e8829286b5ca4c0fb92bc8a739913ad0
Publikováno v:
Zhongguo Jianchuan Yanjiu, Vol 19, Iss 1, Pp 75-83 (2024)
ObjectiveAiming at the uncertainty of model perturbation and external interference in unmanned surface vehicles (USVs), an improved model-free adaptive control (MFAC) method suitable for the heading control of USVs is proposed. MethodsBased on the ex
Externí odkaz:
https://doaj.org/article/3c78e78e53114d9f97c799260dc78fda
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionResearch indicates that individuals experiencing hemorrhagic stroke face a greater likelihood of developing lower extremity deep vein thrombosis (DVT) compared to those with ischemic stroke. This study aimed to assess the predictive capac
Externí odkaz:
https://doaj.org/article/3277293daa674548b5cdfa257115209f
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 13, Iss 6, Pp 640-659 (2023)
Radix Bupleuri (RB) is commonly used to treat depression, but it can also lead to hepatotoxicity after long-term use. In many anti-depression prescriptions, RB is often used in combination with Radix Paeoniae Alba (RPA) as an herb pair. However, whet
Externí odkaz:
https://doaj.org/article/b03dc8a8bfd24f1baf084f485fa1becc
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
In recent years, considerable achievements have been made in pediatric oncology with the innovation and development of antitumor drugs. However, compared to adults, children as a special group have not yet matured fully in terms of liver and kidney f
Externí odkaz:
https://doaj.org/article/dbaf70261acf4b42b71207e2603d5ba8
Autor:
Yu Yin, Conghui Shan, Qianguang Han, Congcong Chen, Zijie Wang, Zhengkai Huang, Hao Chen, Li Sun, Shuang Fei, Jun Tao, Zhijian Han, Ruoyun Tan, Min Gu, Xiaobing Ju
Publikováno v:
Frontiers in Nutrition, Vol 10 (2024)
BackgroundChronic kidney disease (CKD) is often accompanied by alterations in the metabolic profile of the body, yet the causative role of these metabolic changes in the onset of CKD remains a subject of ongoing debate. This study investigates the ca
Externí odkaz:
https://doaj.org/article/490f1dd9ec0e4a918ca06df6063118fb
Autor:
Yanguan Guo, Jiaxin Tian, Yongjian Guo, Cong Wang, Congcong Chen, Songwang Cai, Wenliang Yu, Binghe Sun, Jin Yan, Zhonghua Li, Jun Fan, Qi Qi, Dongmei Zhang, Weilin Jin, Zichun Hua, Guo Chen
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113511- (2023)
Summary: KRAS mutations are frequently detected in non-small cell lung cancers (NSCLCs). Although covalent KRASG12C inhibitors have been developed to treat KRASG12C-mutant cancers, effective treatments are still lacking for other KRAS-mutant NSCLCs.
Externí odkaz:
https://doaj.org/article/9e805ddd99bd46528a03270fc5c0833e
CYP1B1 inhibits ferroptosis and induces anti-PD-1 resistance by degrading ACSL4 in colorectal cancer
Autor:
Congcong Chen, Yabing Yang, Yanguan Guo, Jiashuai He, Zuyang Chen, Shenghui Qiu, Yiran Zhang, Hui Ding, Jinghua Pan, Yunlong Pan
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-9 (2023)
Abstract Immune checkpoint blockade (ICB) is a promising treatment strategy for colorectal cancer (CRC) patients. However, most CRC patients do not response well to ICB therapy. Increasing evidence indicates that ferroptosis plays a critical role in
Externí odkaz:
https://doaj.org/article/ea07eefdfe92474bb70e0e82e1f582b4