Zobrazeno 1 - 10
of 309
pro vyhledávání: '"Cong Xiang"'
Autor:
Cong Xiang, Li Chen, Shilei Zhu, Yue Chen, Haodong Huang, Chunmao Yang, Yugang Chi, Yanzhou Wang, Yunlong Lei, Xiongwei Cai
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-16 (2024)
Abstract Ovarian cancer, the second most leading cause of gynecologic cancer mortality worldwide, is challenged by chemotherapy resistance, presenting a significant hurdle. Pyroptosis, an inflammation-linked programmed cell death mediated by gasdermi
Externí odkaz:
https://doaj.org/article/54fa896369d34128bbc99e9843c151b9
Autor:
Xinran Li, Xiao Li, Cong Xiang, Jin Cao, Jiansheng Guo, Shilei Zhu, Jingyi Tan, Lijing Wang, Chun Gao, Shengduo Liu, Lifeng Zhao, Bo Yuan, Pinglong Xu, Bing Yang, Dali Li, Bin Zhao, Xin-Hua Feng
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114728- (2024)
Summary: Pyroptosis, a pro-inflammatory form of programmed cell death, is crucial for host defense against pathogens and danger signals. Proteolytic cleavage of gasdermin proteins B–E (GSDMB–GSDME) is well established as a trigger for pyroptosis,
Externí odkaz:
https://doaj.org/article/ab33ba34789240a5ae1368358e27c082
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
The synthesis of pseudo-healthy images, involving the generation of healthy counterparts for pathological images, is crucial for data augmentation, clinical disease diagnosis, and understanding pathology-induced changes. Recently, Generative Adversar
Externí odkaz:
https://doaj.org/article/f01ad8c7d73e42faa0a319cd087d9082
Autor:
Xinran Li, Cong Xiang, Shilei Zhu, Jiansheng Guo, Chang Liu, Ailian Wang, Jin Cao, Yan Lu, Dante Neculai, Pinglong Xu, Xin-Hua Feng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Lysosomal Storage Disorders (LSDs), which share common phenotypes, including enlarged lysosomes and defective lysosomal storage, are caused by mutations in lysosome-related genes. Although gene therapies and enzyme replacement therapies have
Externí odkaz:
https://doaj.org/article/a1738fc17a174dfaa7178f18c93ad607
Autor:
Yanling Luo, Xiaolian Gao, Mingzhong Xiao, Fen Yang, Xinhong Zhu, Guiyuan Qiao, Cong Xiang, Junxiu Tao
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
IntroductionPrevious studies have found that diet’s inflammatory potential is related to various diseases. However, little is known about its relationship with gallstones. The present study aims to investigate the relationship between dietary infla
Externí odkaz:
https://doaj.org/article/c2a6b5b8e06240c7b4ccca980c3aefb2
Autor:
Yannan Zhang, Fangfang Zheng, Fan Wang, Xingqian Liu, Cong Xiang, Shiyu Fu, Kun Shen, Geng Liu
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 2962 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is associated with enhanced aerobic glycolysis through elevated glucose uptake and the upregulated expression of genes encoding rate-limiting glycolytic enzymes. However, the direct impact of altered glycolytic
Externí odkaz:
https://doaj.org/article/e00ef1b7183349e6ad80105925cc9541
Autor:
Yinyin Xie, Yannan Zhang, Aina Sun, Yamei Peng, Weikang Hou, Cong Xiang, Guoxin Zhang, Beibei Lai, Xiaoshuang Hou, Fangfang Zheng, Fan Wang, Geng Liu
Publikováno v:
Redox Biology, Vol 56, Iss , Pp 102447- (2022)
The regulation of mitochondria function and health is a central node in tissue maintenance, ageing as well as the pathogenesis of various diseases. However, the maintenance of an active mitochondrial functional state and its quality control mechanism
Externí odkaz:
https://doaj.org/article/c9f5e382db92494a801e247f6c91b1bf
Autor:
Li, Xingquan, Tao, Simin, Huang, Zengrong, Chen, Shijian, Zeng, Zhisheng, Ni, Liwei, Huang, Zhipeng, Zhuang, Chunan, Wu, Hongxi, Li1, Weiguo, Zhao, Xueyan, Liu, He, Long, Shuaiying, He, Wei, Liu, Bojun, Gan, Sifeng, Yu, Zihao, Liu, Tong, Miao, Yuchi, Yan, Zhiyuan, Wang, Hao, Zhao, Jie, Li, Yifan, Liu, Ruizhi, Lin, Xiaoze, Yang, Bo, Xue, Zhen, Huang, Fuxing, Yang, Zonglin, Wu, Zhenggang, Li, Jiangkao, Liu, Yuezuo, Peng, Ming, Qiu, Yihang, Wu, Wenrui, Shao, Zheqing, Mo, Kai, Liu, Jikang, Liang, Yuyao, Zhang, Mingzhe, Ma, Zhuang, Cong, Xiang, Huang, Daxiang, Luo, Guojie, Li, Huawei, Shen, Haihua, Chen, Mingyu, Bu, Dongbo, Zhu, Wenxing, Cai, Ye, Xiong, Xiaoming, Jiang, Ying, Heng, Yi, Zhang, Peng, Xie, Biwei, Bao, Yungang
Open-source EDA shows promising potential in unleashing EDA innovation and lowering the cost of chip design. This paper presents an open-source EDA project, iEDA, aiming for building a basic infrastructure for EDA technology evolution and closing the
Externí odkaz:
http://arxiv.org/abs/2308.01857
Publikováno v:
Cell Reports, Vol 13, Iss 5, Pp 888-897 (2015)
Chronic inflammation promotes the development and progression of various epithelial tumors. Wild-type p53 suppresses inflammation, but it is unclear whether the role of p53 in suppression of inflammation is linked to its tumor suppression function. H
Externí odkaz:
https://doaj.org/article/ddda718502514adfac3812fb10666a69
Publikováno v:
Advances in Mechanical Engineering, Vol 8 (2016)
This study aims to investigate the characteristics of adaptability to stratum for thrust system in tunneling machines in composite stratum. Initially, variation coefficient thrust model has been constructed on the basis of a mechanical model. By anal
Externí odkaz:
https://doaj.org/article/cad00ce9e1fe462289a90eb5ae18fb2a