The design of chronic toxicology studies of monoclonal antibodies: Implications for the reduction in use of non-human primates

Autor: Chapman, Kathryn L., Andrews, Laura, Bajramovic, Jeffrey J., Baldrick, Paul, Black, Lauren E., Bowman, Christopher J., Buckley, Lorrene A., Coney, Lee A., Couch, Jessica, Maggie Dempster, A., de Haan, Lolke, Jones, Keith, Pullen, Nick, de Boer, Anne Seitske, Sims, Jennifer, Ian Ragan, C.

Publikováno v: In Regulatory Toxicology and Pharmacology March 2012 62(2):347-354

Assessment of hepatic steatosis by transplant surgeon and expert pathologist: A prospective, double-blind evaluation of 201 donor livers

Autor: Charles Lassman, Johnny C. Hong, Ronald W. Busuttil, Abbas Rana, Jason A. Wertheim, Coney Lee, Bita V. Naini, Vatche G. Agopian, Jeffrey Gornbein, Ali Zarrinpar, Fady M. Kaldas, Hasan Yersiz, Henrik Petrowsky, Gabriel T. Schnickel

Publikováno v: Liver Transplantation. 19:437-449

An accurate clinical assessment of hepatic steatosis before transplantation is critical for successful outcomes after liver transplantation, especially if a pathologist is not available at the time of procurement. This prospective study investigated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::974b8c4ac908f17c0fc85ce0c514db0d
https://doi.org/10.1002/lt.23615

A rapid, reproducible, noninvasive predictor of liver graft survival

Autor: Ronald W. Busuttil, Emily Noguchi, Ali Zarrinpar, Hasan Yersiz, Vatche G. Agopian, Coney Lee, Douglas G. Farmer, Fady M. Kaldas

Publikováno v: Journal of Surgical Research, vol 197, iss 1
Zarrinpar, A; Lee, C; Noguchi, E; Yersiz, H; Agopian, VG; Kaldas, FM; et al.(2015). A rapid, reproducible, noninvasive predictor of liver graft survival. Journal of Surgical Research, 197(1), 183-190. doi: 10.1016/j.jss.2015.03.093. UCLA: Retrieved from: http://www.escholarship.org/uc/item/0fm9037s

© 2015 Elsevier Inc. All rights reserved. Background Clinical and laboratory criteria are not reliable predictors of deceased donor liver graft quality. Intraoperative assessment of experienced surgeons is the gold standard. Standardizing and quanti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d48fbef6962fec9f502c63116cc758
https://escholarship.org/uc/item/0fm9037s

Activation of Cyclic Adenosine Monophosphate-Dependent Protein Kinase A Signaling Prevents Liver Ischemia/Reperfusion Injury in Mice

Autor: Xiu-Da Shen, Bibo Ke, Ronald W. Busuttil, Yu Zhang, William W. Chang, Feng Gao, Coney Lee, Jerzy W. Kupiec-Weglinski, Cynthia Y. Huang, Haofeng Ji

Hepatic ischemia/reperfusion injury (IRI) occurs in multiple clinical settings, including liver transplantation. The cyclic adenosine monophosphate (cAMP)-dependent protein kinase A (PKA) pathway inhibits hepatocellular apoptosis and regulates toll-l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef990dc8941bfbf576ee9bd85b791b71
https://europepmc.org/articles/PMC4186257/

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