Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Conelius Ngwa"'
Autor:
Afzal Misrani, Conelius Ngwa, Abdullah Al Mamun, Romana Sharmeen, Kanaka Valli Manyam, Rodney M. Ritzel, Louise McCullough, Fudong Liu
Publikováno v:
Brain Research Bulletin, Vol 207, Iss , Pp 110864- (2024)
Ischemic stroke induced inflammatory responses contribute significantly to neuronal damage and stroke outcomes. CD200 ligand and its receptor, CD200R, constitute an endogenous inhibitory signaling that is being increasingly recognized in studies of n
Externí odkaz:
https://doaj.org/article/8edfead9bf6042f38650d8f14ddb892d
Autor:
Shaohua Qi, Conelius Ngwa, Diego A. Morales Scheihing, Abdullah Al Mamun, Hilda W. Ahnstedt, Carson E. Finger, Gabriela Delevati Colpo, Romana Sharmeen, Youngran Kim, HuiMahn A. Choi, Louise D. McCullough, Fudong Liu
Publikováno v:
Biology of Sex Differences, Vol 12, Iss 1, Pp 1-10 (2021)
Abstract Background Sex differences in COVID-19 are increasingly recognized globally. Although infection rates are similar between the sexes, men have more severe illness. The mechanism underlying these sex differences is unknown, but a differential
Externí odkaz:
https://doaj.org/article/a4dbb628b05d41ec91e3d1192f4fa6ee
Autor:
Shaohua Qi, Abdullah Al Mamun, Conelius Ngwa, Sharmeen Romana, Rodney Ritzel, Arthur P. Arnold, Louise D. McCullough, Fudong Liu
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background Stroke is a sexually dimorphic disease. Previous studies have found that young females are protected against ischemia compared to males, partially due to the protective effect of ovarian hormones, particularly estrogen (E2). Howev
Externí odkaz:
https://doaj.org/article/b9fb8ca025c843b589b57f69b93d6f97
Publikováno v:
Cells, Vol 10, Iss 2, p 276 (2021)
Background: Interferon Regulatory Factor (IRF) 5 and 4 play a determinant role in regulating microglial pro- and anti-inflammatory responses to cerebral ischemia. How microglial IRF5 and IRF4 signaling are activated has been elusive. We hypothesized
Externí odkaz:
https://doaj.org/article/50a34b88620945e7894374910ea226fc
Publikováno v:
Aging. 14:6047-6065
Numerous neurochemical changes occur with aging and stroke mainly affects the elderly. Our previous study has found interferon regulatory factor 5 (IRF5) and 4 (IRF4) regulate neuroinflammation in young stroke mice. However, whether the IRF5-IRF4 reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d30e1818b6cf7a5bdb18c09027a791fd
https://doi.org/10.18632/aging.204216
https://doi.org/10.18632/aging.204216
Autor:
Abdullah Al Mamun, Louise D. McCullough, Fudong Liu, Shaohua Qi, Conelius Ngwa, Saumil Datar, Romana Sharmeen, Yan Xu, Pedram Honarpisheh
Publikováno v:
Stroke
Background and Purpose: CD200 (cluster of differentiation 200), a highly glycosylated protein primarily expressed on neurons in the central nervous system, binds with its receptor CD200R to form an endogenous inhibitory signal against immune response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a1533a31d960965a939a4a2882ad62
https://doi.org/10.1161/strokeaha.120.032374
https://doi.org/10.1161/strokeaha.120.032374
Autor:
Sharmeen Romana, Fudong Liu, Shaohua Qi, Abdullah Al Mamun, Conelius Ngwa, Louise D. McCullough, Arthur P. Arnold, Rodney M. Ritzel
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Stroke is a sexually dimorphic disease. Previous studies have found that young females are protected against ischemia compared to males, partially due to the protective effect of ovarian hormones, particularly estrogen (E2). However, there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90739b466e39a2f65ee2353599c496e1
https://doaj.org/article/b9fb8ca025c843b589b57f69b93d6f97
https://doaj.org/article/b9fb8ca025c843b589b57f69b93d6f97
Autor:
Shaohua Qi, Conelius Ngwa, Abdullah Al Mamun, Sharmeen Romana, Ting Wu, Sean P. Marrelli, Arthur P. Arnold, Louise D. McCullough, Fudong Liu
Post-menopausal women become vulnerable to stroke and have poorer outcomes and higher mortality than age-matched men and previous studies suggested that sex chromosomes play a vital role in mediating stroke sensitivity in the aged. It is unknown if t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546412465f004f6943453701729107b4
https://doi.org/10.21203/rs.3.rs-1694000/v1
https://doi.org/10.21203/rs.3.rs-1694000/v1
Publikováno v:
Stroke. 53
Introduction: Stroke is a sexually dimorphic disease. Stroke sensitivity in the elderly is altered by the decline of estrogen levels in females. Our previous studies suggested a X chromosomal effect on stroke sensitivity in aged mice; however, these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8de2b2eed9ca8b7c7edda7d661502a7
https://doi.org/10.1161/str.53.suppl_1.82
https://doi.org/10.1161/str.53.suppl_1.82
Publikováno v:
Stroke. 53
Introduction: Inflammatory responses are a fundamental pathological consequence of stroke, in which microglial activation plays a central role. Our previous study has found interferon regulatory factor 5 (IRF5) and 4 (IRF4) regulate microglial activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aa3239149a76c8fcd050ae643ef7729
https://doi.org/10.1161/str.53.suppl_1.84
https://doi.org/10.1161/str.53.suppl_1.84