Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Conditional reprogramming"'
Publikováno v:
Cell Insight, Vol 3, Iss 6, Pp 100201- (2024)
Preclinical models serve as indispensable tools in translational medicine. Specifically, patient-derived models such as patient-derived xenografts (PDX), induced pluripotent stem cells (iPSC), organoids, and recently developed technique of conditiona
Externí odkaz:
https://doaj.org/article/cfb99bcf16be4237ba69eb3ddebb660d
Publikováno v:
Cell Insight, Vol 3, Iss 1, Pp 100149- (2024)
Intravesical infusion of chemotherapeutics is highly recommended by several clinical guidelines for treating nonmuscle invasive bladder cancer (NMIBC). However, cytotoxic chemotherapeutics can cause a series of side effects, which greatly limits thei
Externí odkaz:
https://doaj.org/article/e75a59b16bce4a8894ec6fe3d364c666
Autor:
Muhammad Assad Riaz, Franziska Louisa Kary, Alexandra Jensen, Felix Zeppernick, Ivo Meinhold-Heerlein, Lutz Konrad
Publikováno v:
Cells, Vol 13, Iss 10, p 811 (2024)
There are fewer investigations conducted on human primary endometrial epithelial cells (HPEECs) compared to human primary endometrial stromal cells (HPESCs). One of the main reasons is the scarcity of protocols enabling prolonged epithelial cell cult
Externí odkaz:
https://doaj.org/article/be0241739ed74ad295b087a74fe9a808
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Siyu Xia, Ming Wu, Xinhao Zhou, Xiu Zhang, Lina Ye, Kang Zhang, Yiyi Kang, Jun Liu, Yunci Zhang, Wang Wu, Dirong Dong, Hong Chen, Hui Li
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-15 (2022)
Abstract Background There is unmet need for effective therapies of intrauterine adhesions (IUAs) that are common cause of menstrual disturbance and infertility, since current clinical procedures do not improve prognosis for patients with moderate to
Externí odkaz:
https://doaj.org/article/68702bcd52bf49d5a477b17d5d3b3d72
Autor:
Zuzanna Bukowy-Bieryłło
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-18 (2021)
Abstract Background Human airway epithelial (HAE) cellular models are widely used in applicative studies of the airway physiology and disease. In vitro expanded and differentiated primary HAE cells collected from patients seem to be an accurate model
Externí odkaz:
https://doaj.org/article/06df67736f0147239ee5a9fb8d12a65e
Autor:
Xiaoxiao Wu, Shengpeng Wang, Mingxing Li, Jing Li, Jing Shen, Yueshui Zhao, Jun Pang, Qinglian Wen, Meijuan Chen, Bin Wei, Parham Jabbarzadeh Kaboli, Fukuan Du, Qijie Zhao, Chi Hin Cho, Yitao Wang, Zhangang Xiao, Xu Wu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1360-1381 (2020)
Long-term primary culture of mammalian cells has been always difficult due to unavoidable senescence. Conventional methods for generating immortalized cell lines usually require manipulation of genome which leads to change of important biological and
Externí odkaz:
https://doaj.org/article/551e8db3f9f24bf1a810326fee42b624
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Faris Alkhilaiwi
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Cancer is a devastating disease that takes the lives of millions of people globally every year. Precision cancer therapy is based on a patient’s tumor histopathology, expression analyses, and/or tumor RNA or DNA analysis. Only 2%–20% of patients
Externí odkaz:
https://doaj.org/article/8e69d877eb734904aa24a9c661439970
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Management of laryngeal and hypopharyngeal squamous cell carcinoma (LHSCC) remains highly challenging due to highly variable therapeutic responses. By establishing an in vitro model for LHSCC based on conditional reprogramming (CR), a cell-culture te
Externí odkaz:
https://doaj.org/article/66749e778f7947faa74fa140003cd0f1