Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Concha, Herrera"'
Autor:
Pedro Justicia-Lirio, María Tristán-Manzano, Noelia Maldonado-Pérez, Carmen Barbero-Jiménez, Marina Cortijo-Gutiérrez, Kristina Pavlovic, Francisco J. Molina-Estevez, Pilar Muñoz, Ana Hinckley-Boned, Juan R. Rodriguez-Madoz, Felipe Prosper, Carmen Griñán-Lison, Saúl A. Navarro-Marchal, Carla Panisello, Julia Muñoz-Ballester, Pedro A. González-Sierra, Concha Herrera, Juan A. Marchal, Francisco Martín
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102308- (2024)
Although chimeric antigen receptor (CAR) T cell therapy has revolutionized type B cancer treatment, efficacy remains limited in various lymphomas and solid tumors. Reinforcing conventional CAR-T cells to release cytokines can improve their efficacy b
Externí odkaz:
https://doaj.org/article/bffb79b98bd04d24b3575e2ddc65fa95
Autor:
Kristina Pavlovic, MDolores Carmona-Luque, Giulia I. Corsi, Noelia Maldonado-Pérez, Francisco J. Molina-Estevez, Esther Peralbo-Santaella, Marina Cortijo-Gutiérrez, Pedro Justicia-Lirio, María Tristán-Manzano, Víctor Ronco-Díaz, Antonio Ballesteros-Ribelles, Alejandro Millán-López, Paula Heredia-Velázquez, Carla Fuster-García, Toni Cathomen, Stefan E. Seemann, Jan Gorodkin, Francisco Martin, Concha Herrera, Karim Benabdellah
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionChimeric antigen receptor-expressing T cells (CAR T cells) have revolutionized cancer treatment, particularly in B cell malignancies. However, the use of autologous T cells for CAR T therapy presents several limitations, including high co
Externí odkaz:
https://doaj.org/article/ba7d41b073e14a1ba7378cf787091c51
Autor:
Olaf Penack, Christophe Peczynski, William Boreland, Jessica Lemaitre, Ksenia Afanasyeva, Brian Kornblit, Manuel Jurado, Carmen Martinez, Annalisa Natale, Jose Antonio Pérez-Simón, Lucia Brunello, Daniele Avenoso, Stefan Klein, Zubeyde Nur Ozkurt, Concha Herrera, Stina Wichert, Patrizia Chiusolo, Eleni Gavriilaki, Grzegorz W. Basak, Hélène Schoemans, Christian Koenecke, Ivan Moiseev, Zinaida Peric
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionExtracorporal Photophoresis (ECP) is in clinical use for steroid-refractory and steroid-dependent acute GVHD (SR-aGVHD). Based on recent Phase-III study results, ruxolitinib has become the new standard of care for SR-aGVHD. Our aim was to
Externí odkaz:
https://doaj.org/article/c87c15a038f44831ac8aefe6cd59a145
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The use of chimeric antigen receptor (CAR) T lymphocytes in the treatment of refractory or relapsed (R/R) B cell acute lymphoblastic leukemia (B-ALL) has meant a radical change in the prognosis of these patients, whose chances of survival with conven
Externí odkaz:
https://doaj.org/article/87c09978df8e4938a2bdbd45c05796b0
Autor:
María Tristán-Manzano, Noelia Maldonado-Pérez, Pedro Justicia-Lirio, Pilar Muñoz, Marina Cortijo-Gutiérrez, Kristina Pavlovic, Rosario Jiménez-Moreno, Sonia Nogueras, M. Dolores Carmona, Sabina Sánchez-Hernández, Araceli Aguilar-González, María Castella, Manel Juan, Concepción Marañón, Juan Antonio Marchal, Karim Benabdellah, Concha Herrera, Francisco Martin
Publikováno v:
Molecular Therapy: Oncolytics, Vol 25, Iss , Pp 335-349 (2022)
Anti-CD19 chimeric antigen receptor (CAR)-T cells have achieved impressive outcomes for the treatment of relapsed and refractory B-lineage neoplasms. However, important limitations still remain due to severe adverse events (i.e., cytokine release syn
Externí odkaz:
https://doaj.org/article/c338abdeeff24c2185714739029ce627
Autor:
Luis Miguel Paco Meza, MDolores Carmona, Sagrario Canadillas, Ana Lopez-Diaz, Francisco Munoz-Lopez, Alvaro Jimenez-Arranz, Ipek Guler, Concha Herrera
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 25, Iss 2, Pp 155-163 (2022)
Objective(s): Adipose tissue-derived mesenchymal stromal cells (ASCs) are useful in cell-based therapy. However, it is well known that diabetes mellitus (DM) alters ASCs’ functionality. The majority of in vitro studies related to ASCs are developed
Externí odkaz:
https://doaj.org/article/23af0e535ce5479c8bc2c6c3b196c726
Autor:
Noelia Maldonado-Pérez, María Tristán-Manzano, Pedro Justicia-Lirio, Elena Martínez-Planes, Pilar Muñoz, Kristina Pavlovic, Marina Cortijo-Gutiérrez, Carlos Blanco-Benítez, María Castella, Manel Juan, Mathias Wenes, Pedro Romero, Francisco J. Molina-Estévez, Concepción Marañón, Concha Herrera, Karim Benabdellah, Francisco Martin
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Autologous T cells expressing the Chimeric Antigen Receptor (CAR) have been approved as advanced therapy medicinal products (ATMPs) against several hematological malignancies. However, the generation of patient-specific CAR-T products delays treatmen
Externí odkaz:
https://doaj.org/article/0c5f4b49a70e4df0958166605f3affa4
Autor:
Karim Benabdellah, Sabina Sánchez‐Hernández, Araceli Aguilar‐González, Noelia Maldonado‐Pérez, Alejandra Gutierrez‐Guerrero, Marina Cortijo‐Gutierrez, Iris Ramos‐Hernández, María Tristán‐Manzano, Pablo Galindo‐Moreno, Concha Herrera, Francisco Martin
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 6, Pp 674-685 (2020)
Abstract Over recent decades, gene therapy, which has enabled the treatment of several incurable diseases, has undergone a veritable revolution. Cell therapy has also seen major advances in the treatment of various diseases, particularly through the
Externí odkaz:
https://doaj.org/article/6ff4ed6867924111889b9c3c4cbf9775
Autor:
Miguel Romero, José Suárez-de-Lezo, Concha Herrera, Manuel Pan, José López-Aguilera, Flor Baeza-Garzón, Francisco Javier Hidalgo-Lesmes, Olga Fernández-López, Juliana Martínez-Atienza, Eva Cebrián, Vanesa Martín-Palanco, Rosario Jiménez-Moreno, Rosario Gutiérrez-Fernández, Sonia Nogueras, Maria Dolores Carmona, Soledad Ojeda, Natividad Cuende, Rosario Mata
Publikováno v:
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Cellular therapies have been increasingly applied to diverse human diseases. Intracoronary infusion of bone marrow-derived mononuclear cells (BMMNC) has demonstrated to improve ventricular function after acute myocardial infarctio
Externí odkaz:
https://doaj.org/article/535659d5f3a34003a06cede5add9ac5d
Autor:
Francisco Moniche, Juan Antonio Cabezas-Rodriguez, Roberto Valverde, Irene Escudero-Martinez, Lucia Lebrato-Hernandez, Blanca Pardo-Galiana, Leire Ainz, Manuel Medina-Rodriguez, Javier de la Torre, Virginia Escamilla-Gomez, Joaquin Ortega-Quintanilla, Elena Zapata-Arriaza, Asier de Albóniga-Chindurza, Fernando Mancha, Miguel-Angel Gamero, Soledad Perez, Raul Espinosa-Rosso, Lucia Forero-Diaz, Miguel Moya, Pilar Piñero, Cristina Calderón-Cabrera, Sonia Nogueras, Rosario Jimenez, Vanesa Martin, Fernando Delgado, Juan-José Ochoa-Sepúlveda, Blanca Quijano, Rosario Mata, Monica Santos-González, Gloria Carmona-Sanchez, Concha Herrera, Alejandro Gonzalez, Joan Montaner
Publikováno v:
The Lancet Neurology. 22:137-146
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04fae13c622f7dd690640eb2b5555718
https://doi.org/10.1016/s1474-4422(22)00526-9
https://doi.org/10.1016/s1474-4422(22)00526-9