Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Concetta Tuccillo"'
Autor:
Chiara Papulino, Ugo Chianese, Ahmad Ali, Gregorio Favale, Concetta Tuccillo, Fortunato Ciardiello, Annabella Di Mauro, Chiara Mignogna, Gerardo Ferrara, Alfredo Budillon, Wouter Leonard Megchelenbrink, Nunzio Del Gaudio, Mariarosaria Conte, Fabrizio Merciai, Pietro Campiglia, Lucia Altucci, Vincenzo Carafa, Eduardo Sommella, Rosaria Benedetti
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Breast cancer manifests as a heterogeneous pathology marked by complex metabolic reprogramming essential to satisfy its energy demands. Oncogenic signals boost the metabolism, modifying fatty acid synthesis and glucose use from th
Externí odkaz:
https://doaj.org/article/e1c9da9a03da4c08b5e34b1d243a2230
Autor:
Caterina De Rosa, Viviana De Rosa, Concetta Tuccillo, Virginia Tirino, Luisa Amato, Federica Papaccio, Davide Ciardiello, Stefania Napolitano, Giulia Martini, Fortunato Ciardiello, Floriana Morgillo, Francesca Iommelli, Carminia Maria Della Corte
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Osimertinib is a third-generation tyrosine kinase inhibitor clinically approved for first-line treatment of EGFR-mutant non-small cell lung cancer (NSCLC) patients. Although an impressive drug response is initially observed, in most of tumor
Externí odkaz:
https://doaj.org/article/7d656ea1f95540b390fad3f80f70a223
Autor:
Caterina De Rosa, Francesca Iommelli, Viviana De Rosa, Giuseppe Ercolano, Federica Sodano, Concetta Tuccillo, Luisa Amato, Virginia Tirino, Annalisa Ariano, Flora Cimmino, Gaetano di Guida, Gennaro Filosa, Alessandra di Liello, Davide Ciardiello, Erika Martinelli, Teresa Troiani, Stefania Napolitano, Giulia Martini, Fortunato Ciardiello, Federica Papaccio, Floriana Morgillo, Carminia Maria Della Corte
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 809 (2024)
Background: Lung cancer (LC), including both non-small (NSCLC) and small (SCLC) subtypes, is currently treated with a combination of chemo- and immunotherapy. However, predictive biomarkers to identify high-risk patients are needed. Here, we explore
Externí odkaz:
https://doaj.org/article/1b66bc9fe5414c49811d29401c6e567b
Autor:
Antonietta Gerarda Gravina, Raffaele Pellegrino, Giovanna Palladino, Annachiara Coppola, Giovanni Brandimarte, Concetta Tuccillo, Fortunato Ciardiello, Marco Romano, Alessandro Federico
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Hericium erinaceus, berberine, and quercetin are effective in experimental colitis. It is unknown whether they can ameliorate inflammatory bowel diseases in humans. This ex vivo study aimed to evaluate the anti-inflammatory potential of a nutraceutic
Externí odkaz:
https://doaj.org/article/8abde5910515439d9857ba0a3bd901a6
Autor:
Carminia Maria Della Corte, Morena Fasano, Vincenza Ciaramella, Flora Cimmino, Robert Cardnell, Carl M. Gay, Kavya Ramkumar, Lixia Diao, Raimondo Di Liello, Giuseppe Viscardi, Vincenzo Famiglietti, Davide Ciardiello, Giulia Martini, Stefania Napolitano, Concetta Tuccillo, Teresa Troiani, Erika Martinelli, Jing Wang, Lauren Byers, Floriana Morgillo, Fortunato Ciardiello
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-10 (2022)
Abstract Background We recently conducted Cetuximab-AVElumab-Lung (CAVE-Lung), a proof-of-concept, translational and clinical trial, to evaluate the combination of two IgG1 monoclonal antibodies (mAb): avelumab, an anti-PD-L1 drug, and cetuximab, an
Externí odkaz:
https://doaj.org/article/bf73de6b841a47699632ecd99243d1f4
Autor:
Antonietta Gerarda Gravina, Mario Romeo, Raffaele Pellegrino, Concetta Tuccillo, Alessandro Federico, Carmelina Loguercio
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background and Aim: Fonte Essenziale® water is a bicarbonate–sulfate–calcium–magnesium water, low in sodium, recognized by the Italian health care system in hydropinotherapy and hepatobiliary dyspepsia therapy. We wanted to explore its effects
Externí odkaz:
https://doaj.org/article/ff5c984c3ad340f6875ebe69316bac58
Autor:
Marcello Dallio, Mario Masarone, Mario Romeo, Concetta Tuccillo, Filomena Morisco, Marcello Persico, Carmelina Loguercio, Alessandro Federico
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Introduction: PNPLA3, TM6SF2, and MBOAT7 genes play a crucial role in non-alcoholic fatty liver disease (NAFLD) development and worsening. However, few data are available on their treatment response influence. The aim of this trial is to explore the
Externí odkaz:
https://doaj.org/article/d3aa2818097d4237b0233d6ebc9d0bdd
Autor:
Giulia Martini, Davide Ciardiello, Marcello Dallio, Vincenzo Famiglietti, Lucia Esposito, Carminia Maria Della Corte, Stefania Napolitano, Morena Fasano, Antonietta Gerarda Gravina, Marco Romano, Carmelina Loguercio, Alessandro Federico, Evaristo Maiello, Concetta Tuccillo, Floriana Morgillo, Teresa Troiani, Massimo Di Maio, Erika Martinelli, Fortunato Ciardiello
Gut microbiota is involved in immune modulation and immune checkpoint inhibitors (ICIs) efficacy. Single-arm phase II CAVE-mCRC and CAVE-LUNG clinical trials investigated cetuximab + avelumab combination in RAS wild-type (WT) metastatic colorectal ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f59960ac3c52b48fc5e8e9c9f422616
http://hdl.handle.net/11591/469898
http://hdl.handle.net/11591/469898
Autor:
Rosa Di Sarno, Stefania Lama, Antonietta Gerarda Gravina, Alessandro Federico, Mario Masarone, Carmelina Loguercio, Marcello Persico, Marcello Dallio, Valentina Cossiga, Concetta Tuccillo, Paola Stiuso, Filomena Morisco
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Nowadays, the nonalcoholic fatty liver disease represents the main chronic liver disease in the Western countries, and the correct medical therapy remains a big question for the scientific community. The aim of our study was to evaluate the effect de
Autor:
Stefania Lama, Francesco Luzza, Francesco Merlino, Marcello Dallio, Michele Caraglia, Paolo Grieco, Paola Stiuso, Alessandro Federico, Concetta Tuccillo, Antonietta Gerarda Gravina, Carmelina Loguercio, Marco Martorano, Ludovico Abenavoli
Publikováno v:
Minerva Gastroenterologica e Dietologica. 66
BACKGROUND Urotensin II (U-II) is a vasoactive peptide that interacts with a specific receptor named UTR. Recently, our group has demonstrated increased UTR expression in both human colon adenocarcinoma cell lines and adenomatous polyps, as well as i