Výsledky vyhledávání - "Concetta Di Febbo"

Reduced Variability to Aspirin Antiplatelet Effect by the Coadministration of Statins in High-Risk Patients for Cardiovascular Disease

Autor: Alessandra Meneguzzi, L. Grossi, Luigia Di Francesco, Annalisa Bruno, Ettore Porreca, Patrizia Ballerini, Stefano Manarini, Cristiano Fava, Giacomo Levantesi, Paola Patrignani, Concetta Di Febbo, Marta L. Capone, Melania Dovizio, Virgilio Evangelista, Pietro Minuz, Stefania Tacconelli, Ilaria D'Agostino

Publikováno v: Clinical Pharmacology & Therapeutics. 104:111-119

We studied the influence of cardiovascular (CV) risk factors, previous CV events, and cotreatments with preventive medicines, on residual platelet thromboxane (TX)B2 production in 182 patients chronically treated with enteric coated (EC)-aspirin (100

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d19de706fab628a9c3af89f89f3de25
https://doi.org/10.1002/cpt.1075

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Differential association between human prostacyclin receptor polymorphisms and the development of venous thrombosis and intimal hyperplasia: a clinical biomarker study

Autor: Scott Gleim, John Hwa, Kent Sierra, Min Ding, Ryan J. Horvath, Stefania Tacconelli, Valeria Moretta, Maria Domenica Guglielmi, Luigia Di Francesco, Jeremiah Stitham, Giovanna Baccante, Paola Patrignani, Karen Douville, Concetta Di Febbo, Marta L. Capone, Ettore Porreca

Publikováno v: Pharmacogenetics and Genomics. 18:611-620

Objective and methods The role of prostacyclin in the development of venous thrombosis and vascular dysfunction in humans is unclear. In patients with deep vein thrombosis (DVT, n=34) and controls (matched for age, sex, indexes of systemic inflammati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f43d25e7ace8b5567144a9e9f75aaeba
https://doi.org/10.1097/fpc.0b013e328301a774

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Severe non-traumatic bleeding, the answer is not in the blood

Autor: Gianfranco Vitullo, Giovanni Davì, Paolo Amerio, Claudio Tana, Concetta Di Febbo, Paolo Di Giosia, Marco Tana

Publikováno v: Internal and emergency medicine. 10(4)

A 92-year-old woman presented to the Emergency Department (ED) with a wide hematoma on the left hemithorax starting from the anterior axillary line and extending to the back. She did not report any history of trauma (Fig. 1). The patient had a histor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e18758ac7e21963279b42eca22abbcf
https://pubmed.ncbi.nlm.nih.gov/25716205

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Circulating leptin is associated with oxidized LDL in postmenopausal women

Autor: Ettore Porreca, Antonio Angelini, Franco Cuccurullo, Maria Domenica Guglielmi, Valeria Moretta, Marcello Di Nisio, Concetta Di Febbo

Publikováno v: Atherosclerosis. 175:139-143

Recently, leptin has been suggested as a possible cause of atherosclerotic disease. In the present study, we have investigated in postmenopausal women (n = 60; age: 52 +/- 13) the relationship between circulating levels of leptin, oxidized LDL (Ox-LD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc8c6db8a0b5207c501cf11a142cc95
https://doi.org/10.1016/j.atherosclerosis.2004.03.010

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Soluble thrombomodulin and vascular adhesion molecule-1 are associated to leptin plasma levels in obese women

Autor: Ettore Porreca, Marcello Di Nisio, Concetta Di Febbo, Franco Cuccurullo, Valeria Moretta, Luigia Fusco

Publikováno v: Atherosclerosis. 172:175-180

Recent studies have suggested that leptin, a plasma protein secreted by adipocytes, may play a role in artherothrombosis. In this study, we tested the hypothesis that leptin contributes to in vivo endothelial dysfunction in obese subjects. A cross-se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44aa69b73bc15c138b63d190a8812dd9
https://doi.org/10.1016/j.atherosclerosis.2003.09.022

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Identification of Three Genetic Risk Factors for Venous Thrombosis Using a Multiplex Allele-Specific PCR Assay: Comparison of Conventional and New Alternative Methods for the Preparation of DNA from Clinical Samples

Autor: Carmine Di Ilio, Antonio Angelini, Giovanna Baccante, Ettore Porreca, Franco Cuccurullo, Marcello Di Nisio, Concetta Di Febbo

Publikováno v: Journal of Thrombosis and Thrombolysis. 16:189-193

The demand for thrombophilia testing at the molecular level is increasing and with it the need for a simple and rapid and cost-saving procedure for the preparation of genomic DNA from whole blood samples. The aim of this paper is to compare the effic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aef15422b7152e155b10c284bbbcbdd
https://doi.org/10.1023/b:thro.0000024057.37588.2a

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Transforming growth factor-β1 levels in hypertensive patients: association with body mass index and leptin1

Autor: Antonio Angelini, Franco Cuccurullo, Francesca Febo, Augusto Di Castelnuovo, Ettore Porreca, Ester Vitacolonna, Giovanna Baccante, Marcello Di Nisio, Concetta Di Febbo

Publikováno v: American Journal of Hypertension. 15:759-765

Background Transforming growth factor-β 1 (TGF-β 1 ) has been demonstrated to be overexpressed in hypertension. Leptin, an adipocyte product, has been shown to play a role in obesity-related hypertension and in vitro studies demonstrated a biologic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5201eecfbe52dfdfa795c7bc9fd380c2
https://doi.org/10.1016/s0895-7061(02)02978-3

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Peripheral blood mononuclear cell production of interleukin-8 and IL-8-dependent neutrophil function in hypercholesterolemic patients

Autor: Rita Sergi, Luciano Orsini, Marcella Reale, Riccardo Bertini, Gianfranco Caselli, Franco Cuccurullo, Giovanna Baccante, Ettore Porreca, Concetta Di Febbo

Publikováno v: Atherosclerosis. 146:345-350

Interleukin-8 is a cytokine produced by mononuclear cells that is involved in polymorphonuclear neutrophil leukocyte (PMN) recruitment and activation. Several studies have previously demonstrated a leukocyte activation during hypercholesterolemia and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b83dce6556e6d6cfba82e4dc47ebfc0f
https://doi.org/10.1016/s0021-9150(99)00160-4

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Transforming growth factor β1 induces IL-1 receptor antagonist production and gene expression in rat vascular smooth muscle cells

Autor: Ettore Porreca, Franco Cuccurullo, Giovanna Baccante, Antonio Angelini, Marcella Reale, Maria Luisa Castellani, Concetta Di Febbo

Publikováno v: Atherosclerosis. 136:377-382

Atherosclerosis is an inflammatory-fibroproliferative process that may represent a possible milieu in which transforming growth factor-beta (TGF-beta) can be involved. Vascular smooth muscle cells (VSMC) may represent a source or a target of a large

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f71bf415210d911d81b6abe2269dbc
https://doi.org/10.1016/s0021-9150(97)00240-2

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Reduced thromboxane biosynthesis in carriers of toll-like receptor 4 polymorphisms in vivo

Autor: Maria Domenica Guglielmi, Concetta Di Febbo, Marta L. Capone, Paola Patrignani, Valeria Moretta, Stefania Tacconelli, Maria G. Sciulli, Ivana Antonucci, Ettore Porreca, Liborio Stuppia, Emanuela Ricciotti, Giovanna Baccante

Publikováno v: Blood. 107:3572-3574

The recent demonstration that platelets express a functional toll-like receptor 4 (TLR4) prompted us to explore the influence of TLR4 polymorphisms (Asp299Gly alone or in combination with Thr399Ile) on thromboxane A(2) (TXA(2)) biosynthesis in vivo.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16086c46cccd2c871ee5af2882c712db
https://doi.org/10.1182/blood-2005-12-4811

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