Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Conception Pedregal"'
Autor:
Mark J. Benvenga, Michael A. Statnick, Karen M. Knitowski, Julie Foss, Miguel A. Toledo, Alfonso Benito, Anke Post, Kirsti Lloyd, Michael Ansonoff, Alma Jiménez, Vanessa N. Barth, Maria Angeles Martinez-Grau, Janice W. Smith, Scott D. Gleason, Celia Lafuente, Linda M. Rorick-Kehn, John T. Catlow, Conception Pedregal, Nuria Diaz, Julie F. Falcone, Kjell A. Svensson, John E. Pintar, Steven Chaney, Xia Li, David L. McKinzie, Benjamin L. Adams, Jeffrey M. Witkin
Publikováno v:
Pharmacology Research & Perspectives
Nociceptin/Orphanin FQ (N/OFQ) is a 17 amino acid peptide whose receptor is designated ORL1 or nociceptin receptor (NOP). We utilized a potent, selective, and orally bioavailable antagonist with documented engagement with NOP receptors in vivo to ass
Autor:
Paul L. Ornstein, Conception Pedregal, André Mann, Celine Verrat, Angèle Schoenfelder, Bernard Bessieres
Publikováno v:
Tetrahedron Letters. 43:7659-7662
A general method based on the sequential reactivities of bis-bromocycloalkenes ( 3–5 ) is proposed for the preparation of phosphonocycloalkanes ( 1a/b–3a/b ), representing structural constrained analogues of AP4. For the synthesis of an additiona
Autor:
Michael A. Statnick, Michael Ansonoff, Alma Jiménez, Ana Benito, Jeffrey M. Witkin, Conception Pedregal, Chalie Hu, Min Song, Yanyun Chen, Miguel A. Toledo, John E. Pintar, Mariangles Martínez-Grau, Celia Lafuente
Publikováno v:
The FASEB Journal. 28
Background: Nociceptin is a 17 amino acid peptide that produces physiological effects through activation of the ORL1 (NOP) receptor. We have identified a novel NOP antagonist (Cpd 1) and found it t...