Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Concepción Vilanova"'
Autor:
Isabel Barasoain, Eva Falomir, Juan Alberto Marco, Miguel Carda, Sandra Torijano-Gutiérrez, José Fernando Díaz, Concepción Vilanova, Santiago Díaz-Oltra, Juan Murga, Mariano Redondo-Horcajo
Publikováno v:
Archiv der Pharmazie. 348:541-547
We here report an investigation of the interactions with tubulin of two types of molecules of a hybrid structural type consisting in a combretastatin A-4 moiety and a simplified pironetin fragment. The cytotoxicities of the molecules on two reference
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4ca453afe2e066ed30981d752808093
https://doi.org/10.1002/ardp.201500106
https://doi.org/10.1002/ardp.201500106
Autor:
Juan Murga, Santiago Díaz-Oltra, J. Alberto Marco, Concepción Vilanova, Eva Falomir, Miguel Carda, Sandra Torijano-Gutiérrez
Publikováno v:
European Journal of Organic Chemistry. 2014:2284-2296
We describe the preparation of a series of hybrid molecules containing a combretastatin A-4 moiety and a pironetin analogue fragment linked by an ester spacer of variable length. The cytotoxic activities of these compounds have been measured and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::102e4ed09d16e25633503594abb630b0
https://doi.org/10.1002/ejoc.201301725
https://doi.org/10.1002/ejoc.201301725
Autor:
Gianluigi Broggini, Cristina Marucci, Maurizio Sironi, Daniele Cartelli, Daniele Passarella, Graziella Cappelletti, Stefano Pieraccini, Silvia Gazzola, Concepción Vilanova, Michael S. Christodoulou, Alessandra Maria Calogero, Federico Dapiaggi
The synthesis of the eight stereoisomers of 6-[2-methoxy-3-(piperidinyl)propyl]-5,6-dihydropyran-2-one is reported. The configuration at C2′ and C6 is induced by a sterecontrolled allylation reaction with DIP-Cl. The general structure is the result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db1f61540ffae793fe1269712830786
http://hdl.handle.net/11383/2051995
http://hdl.handle.net/11383/2051995
Autor:
Sandra, Torijano-Gutiérrez, Concepción, Vilanova, Santiago, Díaz-Oltra, Juan, Murga, Eva, Falomir, Miguel, Carda, Mariano, Redondo-Horcajo, José Fernando, Díaz, Isabel, Barasoain, Juan Alberto, Marco
Publikováno v:
Archiv der Pharmazie. 348(8)
We here report an investigation of the interactions with tubulin of two types of molecules of a hybrid structural type consisting in a combretastatin A-4 moiety and a simplified pironetin fragment. The cytotoxicities of the molecules on two reference
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fed392a3ecc5bec54e2d3c953aac001c
https://pubmed.ncbi.nlm.nih.gov/26085125
https://pubmed.ncbi.nlm.nih.gov/26085125
Autor:
Miguel Carda, Santiago Díaz-Oltra, Eva Falomir, J. Alberto Marco, Juan Murga, Concepción Vilanova
Publikováno v:
Bioorganicmedicinal chemistry letters. 25(16)
A small group of hybrid molecules composed of a colchicine moiety and a pironetin analogue fragment have been investigated for their ability to inhibit the expression of the VEGF, hTERT and c-Myc genes. The VEGF gene is involved in the generation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e539d2f4d0731f16b470ee2e6b8582
https://pubmed.ncbi.nlm.nih.gov/26094121
https://pubmed.ncbi.nlm.nih.gov/26094121
Autor:
Juan Murga, Mariano Redondo-Horcajo, Isabel Barasoain, J. Fernando Díaz, Miguel Carda, Santiago Díaz-Oltra, Eva Falomir, J. Alberto Marco, Concepción Vilanova
Publikováno v:
Repositori Universitat Jaume I
Universitat Jaume I
Digital.CSIC. Repositorio Institucional del CSIC
instname
Universitat Jaume I
Digital.CSIC. Repositorio Institucional del CSIC
instname
We here report the synthesis of a series of 12 hybrid molecules composed of a colchicine moiety and a pironetin analogue fragment. The two fragments are connected through an ester-amide spacer of variable length. The cytotoxic activities of these com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7529e7ba71ba768f3ed7ab76a70d24d7
http://hdl.handle.net/10261/251451
http://hdl.handle.net/10261/251451