Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Concepción Peraire"'
Autor:
Concepción Peraire, Álvaro Gimeno, Beatriz Clares, Roser Sanz, Mireia Mallandrich, Ana C. Calpena
Publikováno v:
International Journal of Pharmaceutics. 477:650-654
According to previous studies reporting the anesthetic/analgesic action of oral topical doxepin administration, this study evaluated a model of buccal permeation to determine the depth of delivery of doxepin into excised porcine buccal mucosa followi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef68ca80fc10bbbc8836971453e16e11
https://doi.org/10.1016/j.ijpharm.2014.10.060
https://doi.org/10.1016/j.ijpharm.2014.10.060
Autor:
Concepción Peraire, Joaquim Ramis, Rosendo Obach, Iñaki F. Trocóniz, Josep-María Cendrós, María J. Garrido
Publikováno v:
The Journal of Clinical Pharmacology. 52:487-498
Acromegaly arises from excessive levels of growth hormone (GH), many of whose effects are mediated by stimulation of secretion of insulin-like growth factor 1 (IGF-1). Synthetic somatostatin analogues inhibit GH secretion. The objective of the study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb3ed6de0c6b21573d998add052fadcc
https://doi.org/10.1177/0091270011399761
https://doi.org/10.1177/0091270011399761
Publikováno v:
Drug Metabolism and Disposition. 40:1268-1278
Irosustat is a first-generation, irreversible, steroid sulfatase inhibitor currently in development for hormone-dependent cancer therapy. To predict clinical drug-drug interactions between irosustat and possible concomitantly administered medications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2595875a2774f0a5cae9ebf82f487d
https://doi.org/10.1124/dmd.111.044271
https://doi.org/10.1124/dmd.111.044271
Autor:
Juhyun Kim, Karla Johanning, Karen A. Veverka, James T. Dalton, Concepción Peraire, Josep Solà
Publikováno v:
Xenobiotica. 41:851-862
Toremifene is an effective agent for the treatment of breast cancer in postmenopausal women and is being evaluated for its ability to prevent bone fractures in men with prostate cancer taking androgen deprivation therapy. Due to the potential for dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdbcc3cd5f476e0098dde3a2d486c169
https://doi.org/10.3109/00498254.2011.590546
https://doi.org/10.3109/00498254.2011.590546
Autor:
Nuria Lloberas, Y. Armendariz, L. Pou, María J. Garrido, Concepción Peraire, Ana Caldés, Josep M. Grinyó, Helena Colom, Iñaki F. Trocóniz, S. Gil-Vernet
Publikováno v:
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
instname
A population pharmacokinetics analysis was performed after intravenous ganciclovir and oral valganciclovir in solid organ transplant patients with cytomegalovirus. Patients received ganciclovir at 5 mg/kg of body weight (5 days) and then 900 mg of va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31fbf8474fc932fc6e25bfbed48a855d
https://doi.org/10.1128/aac.00085-09
https://doi.org/10.1128/aac.00085-09
Autor:
Leyanis Rodríguez-Vera, Carlos Orlando Jacobo‐Cabral, Helena Colom Codina, Concepción Peraire Guitart, Niurys de Castro Suárez, Mayra Ramos-Suzarte, Eduardo Fernández-Sánchez, Jorge Luis Soriano, Gilberto Castañeda Hernández
Publikováno v:
Journal of clinical pharmacology. 55(8)
This study aimed (1) to develop a semimechanistic pharmacokinetic (PK) model for nimotuzumab in patients with advanced breast cancer and (2) to identify demographic, biochemical, and clinical predictive factors of the PK variability. Data from a phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2655d32d728594007825ae0b2388f5
https://pubmed.ncbi.nlm.nih.gov/25760761
https://pubmed.ncbi.nlm.nih.gov/25760761
Autor:
Iñaki F. Trocóniz, Rosendo Obach, Cristina Segura, Concepción Peraire, María J. Garrido, Josep-María Cendrós, Paola Principe
Publikováno v:
Cancer Chemotherapy and Pharmacology. 57:727-735
Purpose: To determine the maximum tolerated dose (MTD) of intravenous (iv) diflomotecan administered once every 3 weeks, and to characterize the relationship between pharmacokinetics and neutropenic effect, using a semi-mechanistic pharmacokinetic/ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba56f04dc028cce0b4b14a8c416d550
https://doi.org/10.1007/s00280-005-0112-6
https://doi.org/10.1007/s00280-005-0112-6
Publikováno v:
Metabolism. 54:1276-1281
Somatostatin analogs are the first-line medical therapy for acromegaly, and the treatment of this disease has been simplified by the development of extended-release formulations of these analogs. Lanreotide is a somatostatin analog that is available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6792985320a668fcf73f04c0c7814f4f
https://doi.org/10.1016/j.metabol.2005.04.014
https://doi.org/10.1016/j.metabol.2005.04.014
Publikováno v:
Pharmaceutical Research. 22:94-102
To estimate the applicability of transdermal drug permeation parameters in a finite-dose model for skin pre-treated with terpenes and to evaluate the enhancing effect of some terpene formulations on alprazolam permeation.In vitro enhancement of alpra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1fa6fc931beb587c224b648b5fa660
https://doi.org/10.1007/s11095-004-9014-2
https://doi.org/10.1007/s11095-004-9014-2
Autor:
Concepción Peraire, M. Montes, Rosendo Obach, M.J. Barbanoj, R. M. Antonijoan, J. Vallès, J. A. Cordero, F. Bismuth, R. CheZérif‐Cheikh, M.‐L. Torres
Publikováno v:
Journal of Pharmacy and Pharmacology. 56:471-476
The pharmacokinetics/tolerability of lanreotide Autogel have been evaluated. Healthy volunteers (n = 24) first received immediate-release lanreotide as a single subcutaneous (s.c.) injection. After two days, 40 or 60 mg lanreotide Autogel was injecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e3df710f829480b1c56adfa17b90d9
https://doi.org/10.1211/0022357023123
https://doi.org/10.1211/0022357023123