Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Concepción Izquierdo"'
Autor:
Pedro Plans-Rubió, Carles Pericas, Ana Maria Avellon, Concepción Izquierdo, Ana Martínez, Núria Torner, Alejandro Martínez, Eva Borrás, Francisco Roig, Pere Godoy, Cristina Rius
Publikováno v:
Vaccines, Vol 12, Iss 6, p 648 (2024)
The aim of this study was to evaluate and compare hepatitis A outbreak-associated healthcare and epidemiological surveillance costs in Spain in two types of autonomous regions during 2010–2018: (1) regions with a prevention strategy based on univer
Externí odkaz:
https://doaj.org/article/79cf730c21ec4bf2b3a7f0f95bc0ddb9
Autor:
María Concepción Izquierdo, Niroshan Shanmugarajah, Samuel X. Lee, Michael J. Kraakman, Marit Westerterp, Takumi Kitamoto, Michael Harris, Joshua R. Cook, Galina A. Gusarova, Kendra Zhong, Elijah Marbuary, InSug O-Sullivan, Nikolaus Rasmus, Stefania Camastra, Terry G. Unterman, Ele Ferrannini, Barry E. Hurwitz, Rebecca A. Haeusler
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 7 (2022)
Multiple beneficial cardiovascular effects of HDL depend on sphingosine-1-phosphate (S1P). S1P associates with HDL by binding to apolipoprotein M (ApoM). Insulin resistance is a major driver of dyslipidemia and cardiovascular risk. However, the mecha
Externí odkaz:
https://doaj.org/article/1bec1268dd814e7492b3638624ca8bed
Autor:
Caroline Gluck, Robert L. Hanson, Chengxiang Qiu, Yi-An Ko, Xin Sheng, Matthew Palmer, Ae Seo Deok Park, Ioannis Mantzaris, Sang Youb Han, Jihwan Park, Amit Verma, Hongzhe Li, Jing Huang, Yong Chen, James Pullman, Katalin Susztak, María Concepción Izquierdo, Yuting Guan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Nature Communications
Epigenetic changes might provide the biological explanation for the long-lasting impact of metabolic alterations of diabetic kidney disease development. Here we examined cytosine methylation of human kidney tubules using Illumina Infinium 450 K array
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128e69c5ffb3ad966aa1c55243e3f539
http://link.springer.com/article/10.1038/s41467-019-10378-8
http://link.springer.com/article/10.1038/s41467-019-10378-8
Publikováno v:
Current Opinion in Lipidology. 29:186-193
Purpose of review Type 2 diabetes is associated with a characteristic dyslipidemia that may exacerbate cardiovascular risk. The causes of, and the effects of new antihyperglycemia medications on, this dyslipidemia, are under investigation. In an unex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793eb225bbcfa0fcdaf73bb99b6ad2fc
https://doi.org/10.1097/mol.0000000000000521
https://doi.org/10.1097/mol.0000000000000521
The FoxO family of transcription factors play an important role in mediating insulin action on glucose, lipid, and lipoprotein metabolism. Liver-specific triple FoxO knockout mice (L-FoxO1,3,4) have defects in expression of genes related to glucose p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b2746ab6b884c51ade65f1abd880fa
https://doi.org/10.1101/804336
https://doi.org/10.1101/804336
Autor:
Miguel A. Garcia-Gonzalez, Red de Investigacion Renal, José M. López-Novoa, Consorcio Madrileño para investigación del fracaso renal agudo, Juan Antonio Moreno, María Concepción Izquierdo, María José Soler, Ana Belen Sanz, Josep M. Cruzado, Alberto Ortiz, Catalina Martin-Cleary, Juliana Draibe, Maria Dolores Sanchez-Niño, Marta Ruiz-Ortega, Laura Garcia-Bermejo
Publikováno v:
European Journal of Pharmacology. 759:205-220
Acute kidney injury (AKI) and chronic kidney disease (CKD) are associated with decreased renal function and increased mortality risk, while the therapeutic armamentarium is unsatisfactory. The availability of adequate animal models may speed up the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc2de6437329fdcf93342e93786f113
https://doi.org/10.1016/j.ejphar.2015.03.026
https://doi.org/10.1016/j.ejphar.2015.03.026
Autor:
Yi-An Ko, Kristin Ware, X. Shirley Liu, Orsolya Giricz, Sanchari Bhattacharya, Yiting Yu, Caroline Hu, Krishna Gundabolu, Ae Seo Deok Park, John M. Greally, Nishanth Vallumsetla, Katalin Susztak, James Pullman, Amit Verma, María Concepción Izquierdo, Masako Suzuki, Davoud Mohtat, Niraj Shenoy, Tushar D. Bhagat
Publikováno v:
Clinical Cancer Research. 20:4349-4360
Purpose: Even though recent studies have shown that genetic changes at enhancers can influence carcinogenesis, most methylomic studies have focused on changes at promoters. We used renal cell carcinoma (RCC), an incurable malignancy associated with m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe27a0121ef1a20b5100e3081ad2359f
https://doi.org/10.1158/1078-0432.ccr-14-0494
https://doi.org/10.1158/1078-0432.ccr-14-0494
Autor:
María Concepción Izquierdo, Beatriz Fernandez-Fernandez, Alberto Ortiz, Maria Dolores Sanchez-Niño, Catalina Martin-Cleary, Usama Elewa, Juan Jesus Carrero
Publikováno v:
Cytokine & Growth Factor Reviews. 25:317-325
CXC chemokine ligand 16 (CXCL16) is a CXC soluble chemokine, an adhesion molecule and a cell surface scavenger receptor. CXCL16 regulates inflammation, tissue injury and fibrosis. Parenchymal renal cells, vascular wall cells, leukocytes and platelets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1859e442393af13783f8371a37b1d468
https://doi.org/10.1016/j.cytogfr.2014.04.002
https://doi.org/10.1016/j.cytogfr.2014.04.002
Akademický článek
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Abstract 1170: Notch pathway is overexpressed and is a therapeutic target in clear cell renal cancer
Autor:
Karim A. Benhadji, Tushar D. Bhagat, James Pullman, Jihwan Park, A. Ari Hakimi, Remi Laurence, Weijuan Li, Justin D. Kaner, Caroline Hu, Niraj Shenoy, Orsolya Giricz, Robert Lopez, Benjamin A. Gartrell, Yi-An Ko, Yiyu Zou, Amit Verma, Matthew Palmer, John M. Greally, Masako Suzuki, Shizeng Huang, Bharvin K. R. Patel, Yiting Yu, Kith Pradhan, Esther Park, Nishanth Vallumsetla, Katalin Susztak, María Concepción Izquierdo
Publikováno v:
Cancer Research. 77:1170-1170
Clear cell renal cell carcinoma (CCRCC) is an incurable malignancy in advanced stages and needs newer therapeutic targets. We conducted a transcriptomic analysis of CCRCCs and matched microdissected renal tubular controls and observed an overexpressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa850d4309610b63e63fa62f2a08a5f0
https://doi.org/10.1158/1538-7445.am2017-1170
https://doi.org/10.1158/1538-7445.am2017-1170