Zobrazeno 1 - 10 of 69 pro vyhledávání: '"Concepció, Soler"'
1
Akademický článek
Bioinformatic analysis of molecular characteristics and oncogenic features of CARD14 in human cancer
Autor: Daniil Bespalov, Dayana Pino, Sònia Vidal-Guirao, Júlia Franquesa, Daniel Lopez-Ramajo, Ingrid Filgaira, Li Wan, Paul A. O’Sullivan, Steven C. Ley, Sonia Vanina Forcales, Juan José Rojas, Mercè Izquierdo-Serra, Concepció Soler, Joan Manils
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Aberrant caspase recruitment domain family member 14 (CARD14) signaling has been strongly associated with inflammatory skin conditions. CARD14 acts as a scaffold protein, ultimately activating the transcription factor NF-KB. Although primari
Externí odkaz: https://doaj.org/article/da771dd4cab84a2b946c10c8d6de5729
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2
Akademický článek
Single loss of a Trp53 allele triggers an increased oxidative, DNA damage and cytokine inflammatory responses through deregulation of IκBα expression
Autor: Laura Marruecos, Joan Manils, Cristina Moreta, Diana Gómez, Ingrid Filgaira, Anna Serafin, Xavier Cañas, Lluís Espinosa, Concepció Soler
Publikováno v: Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Abstract Dose of Trp53, the main keeper of genome stability, influences tumorigenesis; however, the causes underlying and driving tumorigenesis over time by the loss of a single p53 allele are still poorly characterized. Here, we found that single p5
Externí odkaz: https://doaj.org/article/36f5ec065d8846e28b72cd7234991a5f
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3
Akademický článek
Exonucleases: Degrading DNA to Deal with Genome Damage, Cell Death, Inflammation and Cancer
Autor: Joan Manils, Laura Marruecos, Concepció Soler
Publikováno v: Cells, Vol 11, Iss 14, p 2157 (2022)
Although DNA degradation might seem an unwanted event, it is essential in many cellular processes that are key to maintaining genomic stability and cell and organism homeostasis. The capacity to cut out nucleotides one at a time from the end of a DNA
Externí odkaz: https://doaj.org/article/3e1222ca04c24e4ebceae8aedc016ddf
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4
Riluzole-Loaded Nanostructured Lipid Carriers for Hyperproliferative Skin Diseases
Autor: Xavier Llorente, Gerard Esteruelas, Lorena Bonilla, Mariana Garnica Agudelo, Ingrid Filgaira, Daniel Lopez-Ramajo, Ruoyi C Gong, Concepció Soler, Marta Espina, Maria Luisa García, Joan Manils, Montserrat Pujol, Elena Sánchez-López
Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8053
Nanocarriers, and especially nanostructured lipid carriers (NLC), represent one of the most effective systems for topical drug administration. NLCs are biodegradable, biocompatible and provide a prolonged drug release. The glutamate release inhibitor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c62e3e385c6159dd76c9c533fdd2c35
http://hdl.handle.net/2445/199761
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8
Chronic adenosine A2A receptor blockade induces locomotor sensitization and potentiates striatal LTD IN GPR37-deficient mice
Autor: Rodrigo A. Cunha, Francisco Ciruela, Xavier Morató, Olga Jáuregui, Francisco Q. Gonçalves, Víctor Fernández-Dueñas, João P. Lopes, Concepció Soler
Publikováno v: Journal of Neurochemistry. 148:796-809
Adenosine A2A receptors (A2A R) play a key role in modulating dopamine-dependent locomotor activity, as heralded by the sensitization of locomotor activity upon chronic A2A R blockade, which is associated with elevated dopamine levels and altered cor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96a5bbaa968b7b9464b7c8fb2af158c4
https://doi.org/10.1111/jnc.14653
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9
Optical control of adenosine A
Autor: Marc, López-Cano, Ingrid, Filgaira, Ernest G, Nolen, Gisela, Cabré, Jordi, Hernando, Dilip K, Tosh, Kenneth A, Jacobson, Concepció, Soler, Francisco, Ciruela
Publikováno v: Pharmacol Res
Psoriasis is a chronic and relapsing inflammatory skin disease lacking a cure that affects approximately 2% of the population. Defective keratinocyte proliferation and differentiation, and aberrant immune responses are major factors in its pathogenes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c06d69a7c1034ca500e43e46a496fec8
https://pubmed.ncbi.nlm.nih.gov/34157422
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10
Single loss of a Trp53 allele triggers an increased oxidative, DNA damage and cytokine inflammatory responses through deregulation of IκBα expression
Autor: Xavier Cañas, Diana Gómez, Laura Marruecos, Lluis Espinosa, Concepció Soler, Joan Manils, Anna Serafín, Cristina Moreta, Ingrid Filgaira
Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Cell Death & Disease
Dose of Trp53, the main keeper of genome stability, influences tumorigenesis; however, the causes underlying and driving tumorigenesis over time by the loss of a single p53 allele are still poorly characterized. Here, we found that single p53 allele
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973ea422b13a226bd9f9b4ec3cdf7dc7
http://hdl.handle.net/2445/176681
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