Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Conatumumab"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Advances in Therapy. 37:4233-4248
Although various therapies are available for the treatment of metastatic colorectal cancer (mCRC), there is lack of head-to-head evidence. Recent studies have demonstrated the efficacy of chemotherapy in combination with different biological agents i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d72e2d69df4e20b8744bac51185903
https://doi.org/10.1007/s12325-020-01447-2
https://doi.org/10.1007/s12325-020-01447-2
Autor:
Kenneth W. Walker, Ian Foltz, Hossein Salimi-Moosavi, Richele Bruno, Fei Lee, Zhulun Wang, Julie M. Bailis, Stephen Smith, Tina Wang, Phillip An
Publikováno v:
J Biol Chem
Transthyretin (TTR) is an abundant homotetrameric serum protein and was selected here for engineering higher-valency molecules because of its compact size, simple structure, and natural propensity to tetramerize. To demonstrate this utility, we fused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec51fc0568cbbb6b6da4786f5d17f8f
https://doi.org/10.1074/jbc.ra120.013135
https://doi.org/10.1074/jbc.ra120.013135
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 20:e944-e946
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9df220826edfea6f97396ab5c60e6cce
https://doi.org/10.1016/j.clml.2020.07.012
https://doi.org/10.1016/j.clml.2020.07.012
Publikováno v:
Cancer Medicine
Evidence has suggested survival benefits of maintenance for advanced NSCLC patients not progressing after first‐line chemotherapy. Additionally, particular first‐line targeted therapies have shown survival improvements in selected populations. Op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f13278da7c929c26accfcef2ea4c81d
https://doi.org/10.1002/cam4.1101
https://doi.org/10.1002/cam4.1101
Publikováno v:
British Journal of Cancer
Background: Despite good initial response to chemotherapy, 30% of Ewing's sarcoma (EWS) patients with localised tumours develop recurrent disease, associated with poor prognosis. The aim of this study was to address this challenge by conducting precl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c017011f01faf120cec402ffb774d79a
https://doi.org/10.1038/bjc.2015.298
https://doi.org/10.1038/bjc.2015.298
Autor:
Brian D. Gray, Koon Y. Pak, Steven Staelens, Leonie Wyffels, Jan Boddaert, Christel Vangestel, Filipe Elvas, Samir Kumar-Singh, Sigrid Stroobants
Publikováno v:
The Journal of nuclear medicine
Molecular imaging of cell death may provide a detailed readout of the cellular response to novel therapies and prognostic information on tumor treatment efficacy, assisting in the design of individualized therapy. We compared the predictive power of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53894fa0ede193cd73dda5288e45732f
https://doi.org/10.2967/jnumed.116.182014
https://doi.org/10.2967/jnumed.116.182014
Publikováno v:
Oncotarget
// Dan-Zeng Ba-Sang 1 , Zi-Wen Long 2, 3 , Hao Teng 1 , Xu-Peng Zhao 1 , Jian Qiu 1 , Ming-Shan Li 1 1 Department of Oncology, Shigatse People’s Hospital, Shigatse 857000, Tibet, P. R. China 2 Department of Gastric Cancer and Soft-Tissue Sarcoma Su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e79b666560151b7c28fe88406466cb06
http://europepmc.org/articles/PMC5356673
http://europepmc.org/articles/PMC5356673
Autor:
Leonie Wyffels, Christel Vangestel, Brian D. Gray, Filipe Elvas, Luca Palmieri, Koon Y. Pak, Steven Staelens, Sigrid Stroobants
Publikováno v:
Nuclear medicine and biology
Introduction [ 99m Tc]duramycin is a SPECT tracer for cell death imaging. We evaluated the impact of kit formulation, purification and species difference on the pharmacokinetic profile and cell death targeting properties of [ 99m Tc]duramycin in orde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9180e877c5d9c4420b3f25b3c003be53
https://hdl.handle.net/10067/1462880151162165141
https://hdl.handle.net/10067/1462880151162165141
Autor:
Rafal Wierzbicki, Francesco Galimi, Susan Cottrell, Paul de Souza, Y. J. Hei, Luis Paz-Ares, Beatrix Bálint, Cheng-Pang Hsu, Jan P. van Meerbeeck, Yang Pan, Tony Sabin, Vincent Haddad, Rodryg Ramlau, Richard H. de Boer
Publikováno v:
Journal of Thoracic Oncology. 8:329-337
Introduction This study evaluated the efficacy, safety, and pharmacokinetics of conatumumab combined with paclitaxel-carboplatin (PC) as first-line treatment for advanced non–small-cell lung cancer (NSCLC). Methods Patients (aged >18 years) with pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aef46d4fa2dbc25c291fce26bbe8561
https://doi.org/10.1097/jto.0b013e31827ce554
https://doi.org/10.1097/jto.0b013e31827ce554