Zobrazeno 1 - 10
of 37
pro vyhledávání: '"ConA, concanavalin A"'
Autor:
Raj Vuppalanchi, Mary F. Paine, Robin J. Marles, Steven J. Casper, Leonard B. Seeff, Bill J. Gurley, Hellen A. Oketch-Rabah, Tieraona Low Dog, Amy L. Roe, Jawad Ahmad, Scott A. Jordan, Gabriel I. Giancaspro, Andrew Stolz, Cynthia V. Rider, Christopher Koh, Richard Ko, Averell H. Sherker, Kan He, Jose Serrano, Robert J. Fontana, Herbert L. Bonkovsky, Víctor M. Navarro, Joseph M. Betz, Theertham P. Rao, Simona Rossi, Mahendra P. Kapoor
Publikováno v:
Toxicology Reports, Vol 7, Iss, Pp 386-402 (2020)
Toxicology Reports
Toxicology Reports
As part of the United States Pharmacopeia’s ongoing review of dietary supplement safety data, a new comprehensive systematic review on green tea extracts (GTE) has been completed. GTEs may contain hepatotoxic solvent residues, pesticide residues, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0d82c68321543dfc2fccf506f4b9cc
http://www.sciencedirect.com/science/article/pii/S2214750019306596
http://www.sciencedirect.com/science/article/pii/S2214750019306596
Autor:
Elizabeth A. Blackburn, Robin L. Cassady-Cain, Cosmin Chintoan-Uta, Andrew G. Bease, Shaun Webb, Mark P. Stevens
Publikováno v:
Bease, A, Blackburn, E, Chintoan-Uta, C, Webb, S, Cassady-Cain, R & Stevens, M 2021, ' Activity of lymphostatin, a lymphocyte inhibitory virulence factor of pathogenic Escherichia coli, is dependent on a cysteine protease motif ', Journal of Molecular Biology . https://doi.org/10.1016/j.jmb.2021.167200
Journal of Molecular Biology
Journal of Molecular Biology
Graphical abstract
Highlights • LifA shares a cysteine protease motif with bacterial toxins and secreted effectors. • C1480A substituted LifA has reduced inhibitory activity against T cells. • LifA is cleaved in T cells and this requires C
Highlights • LifA shares a cysteine protease motif with bacterial toxins and secreted effectors. • C1480A substituted LifA has reduced inhibitory activity against T cells. • LifA is cleaved in T cells and this requires C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87608baab368015e681c294b17c6c693
https://www.pure.ed.ac.uk/ws/files/225282269/1_s2.0_S0022283621004332_main.pdf
https://www.pure.ed.ac.uk/ws/files/225282269/1_s2.0_S0022283621004332_main.pdf
Autor:
Qing Yu, Jillian Johnson, Qinying Yu, Junfeng Huang, Cynthia M. Carlsson, Xiaofang Zhong, Sanjay Asthana, Lingjun Li, Richard David Shipman, Ozioma C. Okonkwo, Zhengwei Chen
Publikováno v:
Molecular & Cellular Proteomics : MCP
As the body fluid that directly interchanges with the extracellular fluid of the central nervous system (CNS), cerebrospinal fluid (CSF) serves as a rich source for CNS-related disease biomarker discovery. Extensive proteome profiling has been conduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab0f15105dab214633df09be315ed80
https://pubmed.ncbi.nlm.nih.gov/33862227
https://pubmed.ncbi.nlm.nih.gov/33862227
Publikováno v:
Journal of Translational Autoimmunity
Journal of Translational Autoimmunity, Vol 3, Iss, Pp 100053-(2020)
Bone and Joint Institute
Journal of Translational Autoimmunity, Vol 3, Iss, Pp 100053-(2020)
Bone and Joint Institute
Rheumatoid Arthritis (RA) is more common and severe in women compared to men. Both women and men with RA express autoantibodies to post-translationally modified antigens, including citrullinated and homocitrullinated proteins or peptides. These autoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f490cb2203ea0d1acbb42353fc584df8
http://europepmc.org/articles/PMC7388343
http://europepmc.org/articles/PMC7388343
Autor:
Yan-Yan Zheng, Ye Wang, Xin Chen, Li-Sha Wei, Han Wang, Tao Tao, Yu-Wei Zhou, Zhi-Hui Jiang, Tian-Tian Qiu, Zhi-Yuan Sun, Jie Sun, Pei Wang, Wei Zhao, Ye-Qiong Li, Hua-Qun Chen, Min-Sheng Zhu, Xue-Na Zhang
Publikováno v:
The Journal of Biological Chemistry
The thymus is the central immune organ, but it is known to progressively degenerate with age. As thymus degeneration is paralleled by the wasting of aging skeletal muscle, we speculated that the thymus may play a role in muscle wasting. Here, using t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a09c8b7d63fb5bd2cf32d6a891cdb8
https://doi.org/10.1016/j.jbc.2021.101516
https://doi.org/10.1016/j.jbc.2021.101516
Publikováno v:
Molecular & Cellular Proteomics : MCP
Glycosylation is a prevalent, yet heterogeneous modification with a broad range of implications in molecular biology. This heterogeneity precludes enrichment strategies that can be universally beneficial for all glycan classes. Thus, choice of enrich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad350657f104086aa3b3bf8fb2be0f8c
https://doi.org/10.1074/mcp.r120.002277
https://doi.org/10.1074/mcp.r120.002277
Autor:
Miyako Nakano, Eiji Miyoshi, Masato Kitano, Kazuki Nakajima, Yoichiro Harada, Saki Itoyama, Yasuhiko Kizuka, Tomoaki Sobajima, Akihiro Harada, Ryo Misaki, Naoyuki Taniguchi
Publikováno v:
The Journal of Biological Chemistry
Glycosylation, the most common posttranslational modification of proteins, is a stepwise process that relies on tight regulation of subcellular glycosyltransferase location to control the addition of each monosaccharide. Glycosyltransferases primaril
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7090ddd326a3716152f1d830ce1d43a5
https://doi.org/10.1016/j.jbc.2021.100354
https://doi.org/10.1016/j.jbc.2021.100354
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 5, Pp 584-604 (2016)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims: Innate immune dysfunction can promote chronic inflammatory diseases of the liver. For example, mice lacking the flagellin receptor Toll-like receptor 5 (TLR5) show microbial dysbiosis and predisposition to high-fat diet (HFD)-induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983f60a89bc033c3b6ac4a6d24c6eaef
Publikováno v:
Regenerative Therapy, Vol 3, Iss C, Pp 11-14 (2016)
Regenerative Therapy
Regenerative Therapy
We have previously reported that multi-cellular heteroaggregates comprising murine pancreatic α (αTC1.6) and β (MIN6-m9) cell lines spontaneously acquired islet-like architecture and displayed higher insulin secretion rates. However, the mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c02a1eb58481b1c6aba33ebe28acf42
Publikováno v:
JHEP Reports, Vol 2, Iss 6, Pp 100165-(2020)
JHEP Reports
JHEP Reports
Summary: Extracellular nucleotides, including ATP, are essential regulators of liver function and serve as danger signals that trigger inflammation upon injury. Ectonucleotidases, which are expressed by liver-resident cells and recruited immune cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12f6bfc7a6b287d1ac669e41c94e625
https://doi.org/10.1016/j.jhepr.2020.100165
https://doi.org/10.1016/j.jhepr.2020.100165