Zobrazeno 1 - 10
of 1 657
pro vyhledávání: '"Computational studies"'
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Cyclin-dependent kinase 2 (CDK2) has been recognized as one of the crucial factors in cell cycle regulation and has been proposed as a potential target for cancer therapies, particularly for colorectal cancer (CRC). Due to the increased incidence rat
Externí odkaz:
https://doaj.org/article/7bdcc13fc7d84dad895a3d4ae5b5603c
Autor:
Kaushal Naithani, Arka Das, Mamta Ushare, Subham Nath, Rashmita Biswas, Anirban Kundu, Kazi Tawsif Ahmed, Utpal Mohan, Subhendu Bhowmik
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
In this study, 1,4-benzothiazine-based bisamide derivatives, a new class of antibacterial agents targeting bacterial peptide deformylase (PDF), were designed and synthesized to combat Staphylococcus aureus infection. Molecular modeling of the designe
Externí odkaz:
https://doaj.org/article/f2791fb55f4244d6b469e3106bd4f56b
Autor:
Wesam H. Abdulaal, Ulfat M. Omar, Mustafa Zeyadi, Dina S. El-Agamy, Nabil A. Alhakamy, Naif A. R. Almalki, Hani Z. Asfour, Mohammed W. Al-Rabia, Abdulrahim A. Alzain, Gamal A. Mohamed, Sabrin R.M. Ibrahim
Publikováno v:
Saudi Pharmaceutical Journal, Vol 32, Iss 6, Pp 102073- (2024)
The current study explored the protective potential of kaempferol 3-sophoroside-7-glucoside (KSG) against acute lung injury (ALI). Pre-treatment with KSG effectively secured mice from ALI and showed similar efficaciousness to dexamethasone. KSG marke
Externí odkaz:
https://doaj.org/article/e862137428dd45f595e625d6092e852d
Publikováno v:
Chemical Physics Impact, Vol 8, Iss , Pp 100492- (2024)
The present paper investigates the effect of concentrations of Zinc Acetate and Sodium hydroxide on mechanical strength of chitosan nano ZnO Films prepared by in-situ method. Novel one pot - green procedure was employed for the synthesis of films. Th
Externí odkaz:
https://doaj.org/article/212b684d44ac4118a7211f867939e6bb
Publikováno v:
Vestnik MGSU, Vol 19, Iss 2, Pp 270-280 (2024)
Introduction. The study presents an approach for detecting and identifying the causes of damage to individual key elements of metal structures of the hydroelectric power plant’s trash-rack structure under anthropogenic dynamic impacts. Strength and
Externí odkaz:
https://doaj.org/article/6be9e55440564f3bb5e40cf398f7ad5f
Autor:
Shaher Bano, Humaira Nadeem, Iqra Zulfiqar, Tamseela Shahzadi, Tayyaba Anwar, Asma Bukhari, Syed Muzzammil Masaud
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30102- (2024)
Many non-steroidal anti-inflammatory drugs (NSAIDs) concurrently inhibit both COX-1 and COX-2, with a preference for specifically targeting COX-2 due to its significant involvement in various pathologies. In addition to COX enzymes, several other tar
Externí odkaz:
https://doaj.org/article/9f15775d79d74d1aae2adef02dd5d4ac
Autor:
Nagwa M. Abdelazeem, Wael M. Aboulthana, Ashraf S. Hassan, Abdulrahman A. Almehizia, Ahmed M. Naglah, Hamad M. Alkahtani
Publikováno v:
Saudi Pharmaceutical Journal, Vol 32, Iss 5, Pp 102025- (2024)
Based on previous developments of our research programs in trying to find new compounds with multiple biological targets such as antioxidant, anti-diabetic, anti-Alzheimer's, and anti-arthritic agents. In the context, a novel series of sulfonamide de
Externí odkaz:
https://doaj.org/article/dda5e90a0f9a4fcd80635c198f8b160e
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/79e96a9b9aba45b097a8bec2722fcf8c
Publikováno v:
Journal of Saudi Chemical Society, Vol 28, Iss 2, Pp 101825- (2024)
Preparation of clean fuel from biomass has a crucial significance on the development and utilization of renewable clean energy. In this study, a multi-stage porous mordenite supported nickel nanoparticles catalyst (Nix%/HMOR) was prepared, which show
Externí odkaz:
https://doaj.org/article/734e5768d2a844deb8aa6a225ce0682d
Autor:
Singh Alka, Singh Nakshatra Bahadur, Priya Kanu, Tomar Richa, Al-Qahtani Mohammed Saeed, Imam Mohammad Tarique, Almalki Ziyad Saeed, Abdulmonem Waleed Al, Yadav Krishna Kumar, Park Hyun-Kyung
Publikováno v:
e-Polymers, Vol 23, Iss 1, Pp 568-79 (2023)
Cancers are complicated sicknesses that happen because of many different things going wrong in cells, and as they get worse, the cells undergo many changes one after another. Nanomedicine is a new way to treat diseases like cancer. Tiny particles cal
Externí odkaz:
https://doaj.org/article/12aa2a9a38854f338aeebdb6ccf86a18