Zobrazeno 1 - 10
of 551
pro vyhledávání: '"Computational Tool"'
Autor:
Adar Yaacov, Gregory Lazarian, Tatjana Pandzic, Simone Weström, Panagiotis Baliakas, Samia Imache, Valérie Lefebvre, Florence Cymbalista, Fanny Baran-Marszak, Shai Rosenberg, Thierry Soussi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Intratumoral heterogeneity is an important clinical challenge because low burden clones expressing specific genetic alterations drive therapeutic resistance mechanisms. We have developed CAVE (cancer-associated variant enrichment), a gene-ag
Externí odkaz:
https://doaj.org/article/245ecc24d1874afcb302e97755ef1cba
Autor:
Minsuk Kim
Publikováno v:
Journal of Analytical Science and Technology, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Urinary exfoliated tumor cells have emerged as promising biomarkers for predicting, diagnosing, and guiding therapy in bladder cancer. Several methodologies based on biological and physical differences between normal cells and malignant tumo
Externí odkaz:
https://doaj.org/article/0cb443ea66fc416eb90836014307e0f2
Autor:
Minsuk Kim
Publikováno v:
Journal of Analytical Science and Technology, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract It is necessary to verify whether nail fold capillaroscopy can be utilized for the early detection of breast cancer. To establish this technology, an animal model was developed, utilizing mice for nail fold observations. Nail fold capillaros
Externí odkaz:
https://doaj.org/article/97ae294151584942bd157e823e5476ba
Autor:
WenJun Zhang
Publikováno v:
Network Biology, Vol 14, Iss 2, Pp 187-214 (2024)
Meta-analysis is a statistical method used in systematic review to quantitatively integrate the results of multiple related studies to obtain a pooled result that can represent these studies. Meta-analysis overcomes the limitations of traditional rev
Externí odkaz:
https://doaj.org/article/14fc5ed3f3c549b5b693714dddf77528
Autor:
WenJun Zhang
Publikováno v:
Network Biology, Vol 14, Iss 2, Pp 100-155 (2024)
Dependent upon the statistical significance p-value and statistical power, the sample size estimation is widely used in various experimental sciences. Nevertheless, the p-value based paradigm, which has resulted in numerous fake conclusions that orig
Externí odkaz:
https://doaj.org/article/4471cf71c4664b74bce35e09f64d91e5
Autor:
Lei Chen, Nathan D. Olson
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/c75d82d6b2f64d6e90eb4f225918e6d3
Autor:
Pengli Cai, Sheng Liu, Dachuan Zhang, Huadong Xing, Mengying Han, Dongliang Liu, Linlin Gong, Qian-Nan Hu
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background The rapid development of synthetic biology relies heavily on the use of databases and computational tools, which are also developing rapidly. While many tool registries have been created to facilitate tool retrieval, sharing, and
Externí odkaz:
https://doaj.org/article/ae970e62b2744278a4dbfc1b880979f3
Autor:
Chao Li, Wen Chu, Rafaqat Ali Gill, Shifei Sang, Yuqin Shi, Xuezhi Hu, Yuting Yang, Qamar U. Zaman, Baohong Zhang
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 21, Iss 1, Pp 108-126 (2023)
The past decade has witnessed a rapid evolution in identifying more versatile clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas) nucleases and their functional variants, as well as in developing precise
Externí odkaz:
https://doaj.org/article/fc87f14f635f4109b9a106a47059a19e
Autor:
Waleed Iqbal, Wanding Zhou
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 21, Iss 1, Pp 48-66 (2023)
Dissecting intercellular epigenetic differences is key to understanding tissue heterogeneity. Recent advances in single-cell DNA methylome profiling have presented opportunities to resolve this heterogeneity at the maximum resolution. While these adv
Externí odkaz:
https://doaj.org/article/a81667cdc9bd48dda26d7dd3753736f2
Publikováno v:
Mathematics, Vol 12, Iss 2, p 336 (2024)
This paper proposes an icon-based methodology for the design of prototype aggregated production planning software that addresses the complexity of multi-process and multi-product production. Aggregate planning is a critical task in production managem
Externí odkaz:
https://doaj.org/article/4d6c5d65b93a42dc91cc79e83a96f5b8