Zobrazeno 1 - 10
of 546
pro vyhledávání: '"Compound c"'
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27641- (2024)
Feline Coronavirus (FCoV) is a viral pathogen of cats and a highly contagious virus. Cats in a cattery can be infected by up to 100%, and even household cats are infected by 20–60%. Some strains of FCoV are known to induce a fatal disease in cats n
Externí odkaz:
https://doaj.org/article/c24c3279f63e4287bdd23fe17797b331
Autor:
Yang Sun, Dengyue Xu, Weidong Yang, Hongquan Zhang, Yi Su, Bin Gao, Xiaowei Zou, Yiming Zhong, Huanwei Sun, Liangbi Xiang
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-10 (2023)
Abstract Background Spinal cord ischemia–reperfusion injury (SCII) is a catastrophic event, which can cause paraplegia in severe cases. In the reperfusion stage, oxidative stress was up-regulated, which aggravated the injury and apoptosis of neuron
Externí odkaz:
https://doaj.org/article/a40a71c19c574b4e9f6651678ef5e0ab
Akademický článek
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Autor:
Meiling Liu, Sunmin Park
Publikováno v:
Nutrients, Vol 16, Iss 8, p 1239 (2024)
This study aimed to investigate the impact of a common non-synonymous gene variant (C>G, rs738409) in patatin-like phospholipase domain-containing 3 (PNPLA3), leading to the substitution of isoleucine with methionine at position 148 (PNPLA3-I148M), o
Externí odkaz:
https://doaj.org/article/8406d366faa6420eab60bdd9af31c008
Autor:
Jin-Yun Zhao, Xiao-Long Sheng, Cheng-Jun Li, Tian Qin, Run-Dong He, Guo-Yu Dai, Yong Cao, Hong-Bin Lu, Chun-Yue Duan, Jian-Zhong Hu
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 7, Pp 1553-1562 (2023)
Treatment with metformin can lead to the recovery of pleiotropic biological activities after spinal cord injury. However, its effect on spinal cord injury in aged mice remains unclear. Considering the essential role of angiogenesis during the regener
Externí odkaz:
https://doaj.org/article/fe5f7ba85664418c92a45648ce18dd01
Publikováno v:
Italian Journal of Animal Science, Vol 21, Iss 1, Pp 1067-1073 (2022)
The aim of this study was to confirm the role of AMP-activated protein kinase (AMPK) in the regulation of post-mortem breast muscle glycolysis in the broiler, we evaluated the effects of intraperitoneal injection of the specific AMPK activator (5-ami
Externí odkaz:
https://doaj.org/article/83a45c1137ec4aa192fea48d21fb998d
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 453 (2023)
AMP-activated protein kinase (AMPK) is the central component of a signalling pathway that senses energy stress and triggers a metabolic switch away from anabolic processes and towards catabolic processes. There has been a prolonged focus in the pharm
Externí odkaz:
https://doaj.org/article/4cc12f77893b430698a324c4d9476bd1
Autor:
Shi-Rong Lin, Qing-Ming Lin, Yu-Jia Lin, Xin Qian, Xiao-Ping Wang, Zheng Gong, Feng Chen, Bin Song
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 10, Pp 2232-2237 (2022)
Bradykinin (BK) is an active component of the kallikrein-kinin system that has been shown to have cardioprotective and neuroprotective effects. We previously showed that BK postconditioning strongly protects rat hippocampal neurons upon restoration o
Externí odkaz:
https://doaj.org/article/9f407447731740df9eb9f8980454578e
Autor:
Ram Hari Pokhrel, Suman Acharya, Jae-Hee Ahn, Ye Gu, Mahesh Pandit, Jong-Oh Kim, Yun-Yong Park, Ben Kang, Hyun-Jeong Ko, Jae-Hoon Chang
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-15 (2021)
Abstract Background AMP-activated protein kinase (AMPK) is a metabolic sensor that maintains energy homeostasis. AMPK functions as a tumor suppressor in different cancers; however, its role in regulating antitumor immunity, particularly the function
Externí odkaz:
https://doaj.org/article/174c1debff074d1ea4f04e0abaa734a8
Publikováno v:
Cell Journal, Vol 23, Iss 2, Pp 174-183 (2021)
Objective: The aim is to examine the effect of metformin in human microvascular endothelial cells exposed to high glucose (HG) concentration and compare them with the effects of other 5' adenosine monophosphate-activated protein kinase (AMPK) modul
Externí odkaz:
https://doaj.org/article/6cf0a855b7f54503b569b282de5884ba