A foundation for reference models for drug combinations with an application to Loewe’s reference model

Autor: Wim De Mulder, Martin Kuiper

Publikováno v: BMC Bioinformatics, Vol 21, Iss 1, Pp 1-11 (2020)

Abstract Background Treating patients with combinations of drugs that have synergistic effects has become widespread practice in the clinic. Drugs work synergistically when the observed effect of a drug combination is larger than the effect predicted

Externí odkaz: https://doaj.org/article/7b161fa49a2e40288435697b4dc20a4e

Proton-irradiated breast cells: molecular points of view

Autor: Valentina Bravatà 1, Francesco P. Cammarata 1, Luigi Minafra 1, Pietro Pisciotta 1, 2, Concetta Scazzone 3, Lorenzo Manti 4, Gaetano Savoca 1, Giada Petringa 1, Giuseppe A.P. Cirrone 2, Giacomo Cuttone 2, Maria C. Gilardi 1, 5, Giusi I. Forte 1, Giorgio Russo 1

Publikováno v: Journal of radiation research 60 (2019): 451–465. doi:10.1093/jrr/rrz032
info:cnr-pdr/source/autori:Valentina Bravatà 1*, Francesco P. Cammarata 1*, Luigi Minafra 1,* Pietro Pisciotta 1,2, Concetta Scazzone 3, Lorenzo Manti 4, Gaetano Savoca 1, Giada Petringa 1,2, Giuseppe A.P. Cirrone 2, Giacomo Cuttone 2, Maria C. Gilardi 1,5, Giusi I. Forte 1 and Giorgio Russo 1/titolo:Proton-irradiated breast cells: molecular points of view./doi:10.1093%2Fjrr%2Frrz032/rivista:Journal of radiation research/anno:2019/pagina_da:451/pagina_a:465/intervallo_pagine:451–465/volume:60
Journal of Radiation Research

Breast cancer (BC) is the most common cancer in women, highly heterogeneous at both the clinical and molecular level. Radiation therapy (RT) represents an efficient modality to treat localized tumor in BC care, although the choice of a unique treatme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6720b709d813dc1672aa535b210cf742
http://hdl.handle.net/10281/279782