Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Complement regulators"'
Autor:
Rachel L. Washburn
Publikováno v:
BioMed, Vol 4, Iss 1, Pp 19-38 (2024)
The organs of the male reproductive tract, including the testis, epididymis, prostate, seminal vesicles, and semen, must provide an immunoregulatory environment conducive to germ cell viability and successful fertilization. Many immune components, su
Externí odkaz:
https://doaj.org/article/e4b184b240a243b185599288ae0a9d42
Autor:
Harriet M. Jackson, Kate E. Foley, Rita O’Rourke, Timothy M. Stearns, Dina Fathalla, B. Paul Morgan, Gareth R. Howell
Publikováno v:
BMC Genetics, Vol 21, Iss 1, Pp 1-16 (2020)
Abstract Background The complement cascade is increasingly implicated in development of a variety of diseases with strong immune contributions such as Alzheimer’s disease and Systemic Lupus Erythematosus. Mouse models have been used to determine fu
Externí odkaz:
https://doaj.org/article/614e55b302c34685b237b64274f950f7
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 61-66 (2019)
Abstract Introduction Levels of complement proteins (CPs) in plasma astrocyte‐derived exosomes (ADEs) that are abnormal in Alzheimer's disease (AD) have not been assessed in mild cognitive impairment (MCI). Methods Participants (n = 20 per group) h
Externí odkaz:
https://doaj.org/article/f4487646af6b4c2e880ba353df3a3c57
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Genetic testing has uncovered rare variants in complement proteins associated with thrombotic microangiopathy (TMA) and C3 glomerulopathy (C3G). Approximately 50% are classified as variants of uncertain significance (VUS). Clinical risk assessment of
Externí odkaz:
https://doaj.org/article/a669c7cafeef4f408eaaed65d1542cc7
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The complement system is an important part of the innate immune system, providing a strong defense against pathogens and removing apoptotic cells and immune complexes. Due to its strength, it is important that healthy human cells are protected agains
Externí odkaz:
https://doaj.org/article/d03dd475e7ff455987e44f3a99cbdc4e
Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Complement, a part of the innate arm of the immune system, is integral to the frontline defense of the host against innumerable pathogens, which includes RNA viruses. Among the major groups of viruses, RNA viruses contribute significantly to the glob
Externí odkaz:
https://doaj.org/article/5285dce3e890487aa886fa63c9caa5fc
Autor:
Magnus Paulsson, Karlhans F. Che, Jonas Ahl, Johan Tham, Linda Sandblad, Margaretha E. Smith, Ingemar Qvarfordt, Yu-Ching Su, Anders Lindén, Kristian Riesbeck
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Pathogens causing pneumonia utilize the complement regulator vitronectin to evade complement-mediated killing. Although vitronectin is associated with several chronic lung diseases, the role of bronchoalveolar vitronectin in pneumonia has not been st
Externí odkaz:
https://doaj.org/article/0033cbeded09497b8469640ea452603c
Akademický článek
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Autor:
Naoki Kawaguchi, Satoshi Kuwabara, Akiyuki Uzawa, Fumiko Oda, Keiichi Himuro, Manato Yasuda, Yukiko Ozawa, Yuta Kojima
Publikováno v:
European Journal of Neurology. 28:314-322
OBJECTIVE To investigate changes in serum complements and their regulators in the pathogenesis of myasthenia gravis (MG). METHODS Forty-four patients with acetylcholine receptor antibody-positive MG, as well as 20 patients with non-inflammatory neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cec4dfd4c51e70ad1cbc8853c4d088b
https://doi.org/10.1111/ene.14500
https://doi.org/10.1111/ene.14500