Zobrazeno 1 - 10
of 368
pro vyhledávání: '"Complement component 5a"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundHeart surgery results in complement activation with the potential for collateral end-organ damage, especially if the protective elements (complement factor H, Apolipoprotein J) are inadequate. Here, we have investigated if peri-operative st
Externí odkaz:
https://doaj.org/article/03fa90eb7364411f95e3d28a7345be17
Autor:
Shirin Emtenani, Maike M. Holtsche, Richard Stahlkopf, Daniel L. Seiler, Timothy Burn, Huiqing Liu, Melissa Parker, Kaan Yilmaz, Hasan O. Dikmen, Markus Huber Lang, Christian D. Sadik, Christian M. Karsten, Nina van Beek, Ralf J. Ludwig, Jörg Köhl, Enno Schmidt
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Bullous pemphigoid (BP), the by far most frequent autoimmune subepidermal blistering disorder (AIBD), is characterized by the deposition of autoantibodies against BP180 (type XVII collagen; Col17) and BP230 as well as complement components at the der
Externí odkaz:
https://doaj.org/article/e8cb36281fae4c35a6c0ba273e085086
Autor:
Jian-Jun Meng, Rong-Hui Tu, Qi Bi, Hong Wen, Dong-Xiao Wang, Yan He, Guo-Qiang Zhong, Jie-Feng
Publikováno v:
Open Medicine, Vol 16, Iss 1, Pp 1552-1563 (2021)
Open Medicine
Open Medicine
Background Activation of the complement component 5a (C5a) and nuclear factor κB (NF-κB) signaling is an important feature of myocardial ischemia/reperfusion (I/R) injury and recent studies show that morphine postconditioning (MP) attenuates the my
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports
Scientific Reports
The aim of the study was to evaluate the significance of metalloproteinase 3 (MMP-3), chemokine CXC ligand 13 (CXCL-13) and complement component 5a (C5a) in different stages of ANCA associated vasculitis (AAV). 89 adults were included into the study.
Publikováno v:
Experimental and Therapeutic Medicine
Doxorubicin (DOX) is an efficacious antineoplastic drug; however, its use is limited due to its cardiotoxicity. Cardiomyocyte senescence is considered to be a key factor in the development of DOX-related cardiomyopathy. Complement component 5a (C5a)
Akademický článek
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Akademický článek
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Autor:
Karen Laliberte, Noah Huizenga, Jillian Rosenthal, Reza Zonozi, John L. Niles, Frank B. Cortazar
Publikováno v:
Kidney International Reports, Vol 5, Iss 4, Pp 542-545 (2020)
Kidney International Reports
Kidney International Reports
Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) is a small vessel necrotizing vasculitis with a predilection for the respiratory tract and kidneys.1,2 Prompt initiation of remission induction immunosuppression is paramount to
Autor:
Robert A. Wood, Amy P. Stallings, Frederic F. Little, Donna S. Hummell, Joshua D. Milner, Allison E. Norton, Kathryn M. Edwards, Kimberly A. Risma
Publikováno v:
The Journal of Allergy and Clinical Immunology
Anaphylaxis to vaccines is historically a rare event. The coronavirus disease 2019 pandemic drove the need for rapid vaccine production applying a novel antigen delivery system: messenger RNA vaccines packaged in lipid nanoparticles. Unexpectedly, pu
Autor:
I. Wayan Sumardika, Hidekazu Iioka, Ken Saito, Satoshi Maruyama, Masakiyo Sakaguchi, Eisaku Kondo
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 12, Pp 1121-1132 (2019)
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 12, Pp 1121-1132 (2019)
Pancreatic invasive ductal adenocarcinoma (PDAC) is a representative intractable malignancy under the current cancer therapies, and is considered a scirrhous carcinoma because it develops dense stroma. Both PODXL1, a member of CD34 family molecules,