Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Complement Evasion"'
Autor:
Jiajia Xu, Long Chen, Siqi Pang, Qiuhong Zhang, Simin Deng, Jiaqi Zhu, Xiabing Chen, Paul R Langford, Qi Huang, Rui Zhou, Lu Li
Publikováno v:
Virulence, Vol 15, Iss 1 (2024)
ABSTRACTPathogenic bacteria have evolved many strategies to evade surveillance and attack by complements. Streptococcus suis is an important zoonotic pathogen that infects humans and pigs. Hyaluronidase (HylA) has been reported to be a potential viru
Externí odkaz:
https://doaj.org/article/1b233dcdb9214915a3947c0a59bbddfb
Autor:
Simin Deng, Junhui Liao, Haojie Li, Jiali Xu, Jingyan Fan, Jing Xia, Jing Wang, Lei Lei, Mianmian Chen, Yue Han, Ruidong Zhai, Chang Zhou, Rui Zhou, Changyong Cheng, Houhui Song
Publikováno v:
Virulence, Vol 15, Iss 1 (2024)
ABSTRACTStreptococcus suis (S. suis), a significant zoonotic bacterial pathogen impacting swine and human, is associated with severe systemic diseases such as streptococcal toxic shock-like syndrome, meningitis, septicaemia, and abrupt fatality. The
Externí odkaz:
https://doaj.org/article/62d7e50c0c6d4bf1a6ff5001a67939a3
Autor:
Anna E. van Beek, Hannah Jeanguenat, Cécile Häberli, Richard B. Pouw, Christina Lamers, Gábor Pál, Péter Gál, Christoph Q. Schmidt, Daniel Ricklin, Jennifer Keiser
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundSchistosomes are highly efficient evaders of human immunity, as evident by their ability to survive in human blood for years. How they protect themselves against the constant attack by a key element of innate immunity, the complement system
Externí odkaz:
https://doaj.org/article/57c8f723b6b34a32a74928707eb54f8b
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
The complement system is a fundamental part of the innate immune system that plays a key role in the battle of the human body against invading pathogens. Through its three pathways, represented by the classical, alternative, and lectin pathways, the
Externí odkaz:
https://doaj.org/article/539a67d5f7ee4e30b93f8b92c6f3951f
Publikováno v:
Virulence, Vol 14, Iss 1 (2023)
ABSTRACTStreptococcus equi subsp. zooepidemicus (SEZ) is a major equine pathogen that causes pneumonia, abortion, and polyarthritis. It can also cause invasive infections in humans. SEZ expresses the M-like protein SzM, which recruits host proteins s
Externí odkaz:
https://doaj.org/article/399ac4bd70d94ab8a06835e26851e20a
Autor:
Sen Li, Yanhua Wang, Rongkun Yang, Xiaotong Zhu, Hongying Bai, Xiaojian Deng, Jiao Bai, Yang Zhang, Yuncai Xiao, Zili Li, Zhengfei Liu, Zutao Zhou
Publikováno v:
Virulence, Vol 14, Iss 1 (2023)
ABSTRACTRiemerella anatipestifer is an important bacterial pathogen in poultry. Pathogenic bacteria recruit host complement factors to resist the bactericidal effect of serum complement. Vitronectin (Vn) is a complementary regulatory protein that inh
Externí odkaz:
https://doaj.org/article/8b3dcc92f0f6457e8611040a7082855f
Akademický článek
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Autor:
Medard Ernest, Thiago F. A. Rosa, Zarna Rajeshkumar Pala, Heather M. Kudyba, Brendan Sweeney, Timo Reiss, Gabriele Pradel, Joel Vega-Rodríguez
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Plasmodium parasites are the etiological agents of malaria, a disease responsible for over half a million deaths annually. Successful completion of the parasite’s life cycle in the vertebrate host and transmission to a mosquito vector is c
Externí odkaz:
https://doaj.org/article/4b070be639a24e2da5a5fc7d4135b9c4
Publikováno v:
Pathogens, Vol 13, Iss 1, p 25 (2023)
Staphylococcus aureus is a significant human pathogen with a formidable propensity for antibiotic resistance. Worldwide, it is the leading cause of skin and soft tissue infections (SSTI), septic arthritis, osteomyelitis, and infective endocarditis or
Externí odkaz:
https://doaj.org/article/8ddfaa46bc1f40c39c9a5acaed90a081
Autor:
Ayman Khattab, Mikel Rezola, Marta Barroso, Mikael Kyrklund, Tero Pihlajamaa, Tobias L. Freitag, Geert-Jan van Gemert, Teun Bousema, Perttu Permi, Ossi Turunen, Robert Sauerwein, Adrian J. F. Luty, Seppo Meri
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The complement system is considered the first line of defense against pathogens. Hijacking complement regulators from blood is a common evasion tactic of pathogens to inhibit complement activation on their surfaces. Here, we report hijacking of the c
Externí odkaz:
https://doaj.org/article/f2b7bff8992c46d0b53b8fb320cfed0c