Glycoconjugate coumarins exploiting metabolism-enhanced fluorescence and preferential uptake: New optical tools for tumor cell staining.

Autor: Iacopini D; Department of Pharmacy, University of Pisa, Via Bonanno Pisano 33, 56126 Pisa, Italy., Santi M; Istituto Nanoscienze-CNR, NEST Laboratory, Piazza San Silvestro 12, 56127 Pisa, Italy., Santangelo MC; Department of Pharmacy, University of Pisa, Via Bonanno Pisano 33, 56126 Pisa, Italy., Sardelli G; Biochemistry Unit, Department of Biology, University of Pisa, 56123 Pisa, Italy., Piazza L; Biochemistry Unit, Department of Biology, University of Pisa, 56123 Pisa, Italy; Institute of Clinical Physiology, National Research Council, 56124 Pisa, Italy., Mosca R; Biochemistry Unit, Department of Biology, University of Pisa, 56123 Pisa, Italy., Comparini LM; Department of Pharmacy, University of Pisa, Via Bonanno Pisano 33, 56126 Pisa, Italy., Granchi C; Department of Pharmacy, University of Pisa, Via Bonanno Pisano 33, 56126 Pisa, Italy., Pineschi M; Department of Pharmacy, University of Pisa, Via Bonanno Pisano 33, 56126 Pisa, Italy., Di Pietro S; Department of Pharmacy, University of Pisa, Via Bonanno Pisano 33, 56126 Pisa, Italy. Electronic address: sebastiano.dipietro@unipi.it., Signore G; Biochemistry Unit, Department of Biology, University of Pisa, 56123 Pisa, Italy; Institute of Clinical Physiology, National Research Council, 56124 Pisa, Italy; Interdepartmental Research Center Nutrafood 'Nutraceuticals and Food for Health', University of Pisa, 56123 Pisa, Italy. Electronic address: giovanni.signore@unipi.it., Di Bussolo V; Department of Pharmacy, University of Pisa, Via Bonanno Pisano 33, 56126 Pisa, Italy.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2024 Dec; Vol. 153, pp. 107836. Date of Electronic Publication: 2024 Sep 19.

Streamlined Stereoselective Entry to (-)-Quinagolide and to 3-Substituted Octahydrobenzo[ g ]-Quinolines.

Autor: Sardelli F; Department of Pharmacy, University of Pisa, Via Bonanno 33, 56126 Pisa, Italy., Comparini LM; Department of Pharmacy, University of Pisa, Via Bonanno 33, 56126 Pisa, Italy., Favero L; Department of Pharmacy, University of Pisa, Via Bonanno 33, 56126 Pisa, Italy., Di Pietro S; Department of Pharmacy, University of Pisa, Via Bonanno 33, 56126 Pisa, Italy., Ryberg P; Chemical Development, Global Pharmaceutical R&D, Ferring Pharmaceuticals A/S, Amager Strandvej 405, DK 2770 Kastrup, Denmark., Pineschi M; Department of Pharmacy, University of Pisa, Via Bonanno 33, 56126 Pisa, Italy.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2024 Feb 16; Vol. 89 (4), pp. 2649-2655. Date of Electronic Publication: 2024 Jan 27.

Development of an asymmetric formal synthesis of (-)-quinagolide via enzymatic resolution and stereoselective iminium ion reduction.

Autor: Comparini LM; Department of Pharmacy, University of Pisa, Via Bonanno 33, 56126 Pisa, Italy. Mauro.pineschi@unipi.it., Menichetti A; Department of Pharmacy, University of Pisa, Via Bonanno 33, 56126 Pisa, Italy. Mauro.pineschi@unipi.it., Favero L; Department of Pharmacy, University of Pisa, Via Bonanno 33, 56126 Pisa, Italy. Mauro.pineschi@unipi.it., Di Pietro S; Department of Pharmacy, University of Pisa, Via Bonanno 33, 56126 Pisa, Italy. Mauro.pineschi@unipi.it., Badalassi F; Chemical Development, Global Pharmaceutical R&D, Ferring Pharmaceuticals A/S, Amager Strandvej 405, DK 2770 Kastrup, Denmark. Per.Ryberg@ferring.com., Ryberg P; Chemical Development, Global Pharmaceutical R&D, Ferring Pharmaceuticals A/S, Amager Strandvej 405, DK 2770 Kastrup, Denmark. Per.Ryberg@ferring.com., Pineschi M; Department of Pharmacy, University of Pisa, Via Bonanno 33, 56126 Pisa, Italy. Mauro.pineschi@unipi.it.

Publikováno v: Organic & biomolecular chemistry [Org Biomol Chem] 2023 Aug 09; Vol. 21 (31), pp. 6389-6396. Date of Electronic Publication: 2023 Aug 09.