Investigation of the effects of P1 on HC-pro-mediated gene silencing suppression through genetics and omics approaches

Autor: Sin-Fen Hu, Wei-Lun Wei, Syuan-Fei Hong, Ru-Ying Fang, Hsin-Yi Wu, Pin-Chun Lin, Neda Sanobar, Hsin-Ping Wang, Margo Sulistio, Chun-Ta Wu, Hsiao-Feng Lo, Shih-Shun Lin

Publikováno v: Botanical Studies, Vol 61, Iss 1, Pp 1-18 (2020)

Abstract Background Posttranscriptional gene silencing (PTGS) is one of the most important mechanisms for plants during viral infection. However, viruses have also developed viral suppressors to negatively control PTGS by inhibiting microRNA (miRNA)

Externí odkaz: https://doaj.org/article/d1a20412ddfc49b582fbc7222a6086c1

Comparative gene co-expression network analysis of epithelial to mesenchymal transition reveals lung cancer progression stages

Autor: Daifeng Wang, John D. Haley, Patricia Thompson

Publikováno v: BMC Cancer, Vol 17, Iss 1, Pp 1-12 (2017)

Abstract Background The epithelial to mesenchymal transition (EMT) plays a key role in lung cancer progression and drug resistance. The dynamics and stability of gene expression patterns as cancer cells transition from E to M at a systems level and r

Externí odkaz: https://doaj.org/article/ee07f52a7574416083e861818c4f4012

Cross-disorder comparative analysis of comorbid conditions reveals novel autism candidate genes

Autor: Leticia Diaz-Beltran, Francisco J. Esteban, Maya Varma, Alp Ortuzk, Maude David, Dennis P. Wall

Publikováno v: BMC Genomics, Vol 18, Iss 1, Pp 1-14 (2017)

Abstract Background Numerous studies have highlighted the elevated degree of comorbidity associated with autism spectrum disorder (ASD). These comorbid conditions may add further impairments to individuals with autism and are substantially more preva

Externí odkaz: https://doaj.org/article/81707eaf82ba4da8a758f0179cd90551

Big Data to Knowledge Analytics Reveals the Zika Virus Epidemic as Only One of Multiple Factors Contributing to a Year-Over-Year 28-Fold Increase in Microcephaly Incidence

Autor: Myriam Patricia Cifuentes, Clara Mercedes Suarez, Ricardo Cifuentes, Noel Malod-Dognin, Sam Windels, Jose Fernando Valderrama, Paul D. Juarez, R. Burciaga Valdez, Cynthia Colen, Charles Phillips, Aramandla Ramesh, Wansoo Im, Maureen Lichtveld, Charles Mouton, Nataša Pržulj, Darryl B. Hood

Publikováno v: UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
International Journal of Environmental Research and Public Health; Volume 19; Issue 15; Pages: 9051

During the 2015–2016 Zika Virus (ZIKV) epidemic in Brazil, the geographical distributions of ZIKV infection and microcephaly outbreaks did not align. This raised doubts about the virus as the single cause of the microcephaly outbreak and led to res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dfc7200d404be421e1b6f9470fecb23
https://pubmed.ncbi.nlm.nih.gov/35897436

ClusterM: a scalable algorithm for computational prediction of conserved protein complexes across multiple protein interaction networks

Autor: Byung-Jun Yoon, Xiaoning Qian, Yijie Wang, Hyundoo Jeong

Publikováno v: BMC Genomics, Vol 21, Iss S10, Pp 1-14 (2020)
BMC Genomics

Background The current computational methods on identifying conserved protein complexes across multiple Protein-Protein Interaction (PPI) networks suffer from the lack of explicit modeling of the desired topological properties within conserved protei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f80b490b0003c055c0830e15f143db13
http://link.springer.com/article/10.1186/s12864-020-07010-1