Non‐Natural MUC1 Glycopeptide Homogeneous Cancer Vaccine with Enhanced Immunogenicity and Therapeutic Activity.

Autor: Guerreiro, Ana^1,2 (AUTHOR), Compañón, Ismael³ (AUTHOR), Lazaris, Foivos S.³ (AUTHOR), Labão‐Almeida, Carlos¹ (AUTHOR), Oroz, Paula³ (AUTHOR), Ghirardello, Mattia³ (AUTHOR), Marques, Marta C.¹ (AUTHOR), Corzana, Francisco³ (AUTHOR) francisco.corzana@unirioja.es, Bernardes, Gonçalo J. L.^1,2,4 (AUTHOR) gb453@cam.ac.uk

Publikováno v: Angewandte Chemie. Sep2024, p1. 9p. 7 Illustrations.

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Molecular basis for bacterial N-glycosylation by a soluble HMW1C-like N-glycosyltransferase.

Autor: Piniello, Beatriz, Macías-León, Javier, Miyazaki, Shun, García-García, Ana, Compañón, Ismael, Ghirardello, Mattia, Taleb, Víctor, Veloz, Billy, Corzana, Francisco, Miyagawa, Atsushi, Rovira, Carme, Hurtado-Guerrero, Ramon

Publikováno v: Nature Communications; 9/18/2023, Vol. 14 Issue 1, p1-15, 15p

Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry

Autor: Ferhati, Xhenti, Jiménez-Moreno, Ester, Hoyt, Emily A., Salluce, Giulia, Cabeza-Cabrerizo, Mar, Navo, Claudio D., Compañón, Ismael, Akkapeddi, Padma, Matos, Maria J., Salaverri, Noelia, Garrido, Pablo, Martínez, Alfredo, Laserna, Víctor, Murray, Thomas V., Jiménez-Osés, Gonzalo, Ravn, Peter, Bernardes, Gonçalo J. L., Corzana, Francisco, 0000-0002-5045-433X, 0000-0001-6940-8803, 0000-0002-1615-6822, 0000-0003-0161-412X, 0000-0002-3470-8299, 0000-0002-5960-8569, 0000-0003-4882-4044, 0000-0003-0105-4337, 0000-0001-6594-8917, 0000-0001-5597-8127

Publikováno v: RIUR. Repositorio Institucional de la Universidad de La Rioja
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Copyright © 2022 The Authors. Published by American Chemical Society
Antibody-drug conjugates (ADCs) are a class of targeted therapeutics used to selectively kill cancer cells. It is important that they remain intact in the bloodstream and rele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602082ac290726aecf4a1ef02e832266

Structural basis for the synthesis of the core 1 structure by C1GalT1

Autor: González-Ramírez, Andrés Manuel, Grosso, Ana Sofia, Yang, Zhang, Compañón, Ismael, Coelho, Helena, Narimatsu, Yoshiki, Clausen, Henrik, Marcelo, Filipa, Corzana, Francisco, Hurtado-Guerrero, Ramon, 0000-0002-5838-0857, 0000-0002-4756-5813, 0000-0003-1428-5695, 0000-0002-0915-5055, 0000-0001-5597-8127, 0000-0002-3122-9401

Publikováno v: RIUR. Repositorio Institucional de la Universidad de La Rioja
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Zaguán. Repositorio Digital de la Universidad de Zaragoza
González-Ramírez, A M, Grosso, A S, Yang, Z, Compañón, I, Coelho, H, Narimatsu, Y, Clausen, H, Marcelo, F, Corzana, F & Hurtado-Guerrero, R 2022, ' Structural basis for the synthesis of the core 1 structure by C1GalT1 ', Nature Communications, vol. 13, no. 1, 2398 . https://doi.org/10.1038/s41467-022-29833-0

LA/P/0140/2020 MX20229-11 BFU2016-75633-P PID2019-105451GB-I00 RTI2018-099592-B-C21 E34_R17 LMP58_18 DNRF107 LA/P/0140/2020 2020.00233.CEECIND 2020.03261.CEECIND ROTEIRO/0031/2013–PINFRA/22161/2016 N°283570 BIOSTRUCTX_5186). Publisher Copyright: �

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0a22fe46c5990d3b306b6ba2e334a3
https://investigacion.unirioja.es/documentos/628009a43333e458234bb7e1