Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Common Thymocyte"'
Publikováno v:
Nature Reviews Immunology. 10:657-663
The thymus produces several types of functionally distinct T cell subsets. However, at a more fundamental level only two genetically distinct T cell lineages exist: the γδ and αß T cell lineages. Precisely how these two T cell lineages are genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad436c9cfb0f4fdad59caef31b7b2f0
https://doi.org/10.1038/nri2820
https://doi.org/10.1038/nri2820
Autor:
Ali Lahjouji, Mohamed Khattab, Fatima Bachir, Mhamed Harif, Siham Cherkaoui, Rajae El Aouad, Ilham Nassereddine, Saadia Zafad, Sanae Bennani
Publikováno v:
International Journal of Pediatrics, Vol 2009 (2009)
International Journal of Pediatrics
International Journal of Pediatrics
We present the incidence and the immunologic characteristics of acute lymphoblastic leukemia (ALL) subsets in Moroccan children. We studied 279 unselected patients below the age of 18 years with newly diagnosed ALL. Cases were classified according to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef08093505ffdd9e6bcf97da2e0448f7
https://doaj.org/article/ee46e4d76f4943509c83bd4ee616931d
https://doaj.org/article/ee46e4d76f4943509c83bd4ee616931d
Autor:
Jonathan Kaye, Parinaz Aliahmad
Publikováno v:
The Journal of Experimental Medicine
CD8+ cytotoxic and CD4+ helper/inducer T cells develop from common thymocyte precursors that express both CD4 and CD8 molecules. Upon T cell receptor signaling, these cells initiate a differentiation program that includes complex changes in CD4 and C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e529ce20eefadfd03d7d3fff488d7040
https://pubmed.ncbi.nlm.nih.gov/18195075
https://pubmed.ncbi.nlm.nih.gov/18195075
Autor:
Caterina Casadio, U. Massazza, Luca Durelli, M. F. Ferrio, R. Cavallo, Giuliano Maggi, L. Bergamini, G. Poccardi, M. Di Summa
Publikováno v:
Annals of Neurology. 27:174-180
Thymocytes express multiple, different surface antigens according to their stage of maturation. Surface differentiation antigens have been studied with the technique of simultaneous dual-color, direct immunofluorescence in the thymuses of 20 patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c36b3575fbb80b5e288f5ce6218d4e
https://doi.org/10.1002/ana.410270213
https://doi.org/10.1002/ana.410270213
Autor:
Ingrid Schmid, Christel H. Uittenbogaart, Loran T. Clement, Thomas C. Boone, Leanne W. Vollger, Sumihiko Higashitani
Publikováno v:
International Immunology. 2:1179-1187
Interleukin-4 (IL-4) is a multifunctional lymphokine which promotes the growth and/or maturation of multiple cell types. We have examined the ability of IL-4 to promote the phenotypic maturation of subsets of human thymocytes. When cultured in serum-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3412d3aa151b0735aa994164798927c2
https://doi.org/10.1093/intimm/2.12.1179
https://doi.org/10.1093/intimm/2.12.1179
Publikováno v:
Blood. 97(1)
The organization and expression of the BCL-6 gene in normal and neoplastic thymic T cells has not been fully determined. We examined 8 precursor T-cell lymphoblastic lymphomas (T-LBLs) and found significant BCL-6 expression in 4 cases. Three of the B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b6f8896f7e32c606807f5732b9ceda
https://pubmed.ncbi.nlm.nih.gov/11133771
https://pubmed.ncbi.nlm.nih.gov/11133771
Autor:
Jean Lemerle, Françoise Valensi, Jerome Ritz, Alain Bernard, Hélène Coppin, Georges Flandrin, Stuart F. Schlossman, Lee M. Nadler, Jean Dausset, Laurence Boumsell, Yolande Richard, Ellis L. Reinherz
Publikováno v:
Blood. 57:1105-1110
A series of monoclonal antibodies was used for the characterization of malignant T cells from 21 patients with lymphoblastic lymphoma (LL). The tumor population from these patients showed a marked degree of phenotypic heterogeneity and a proportion (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87bc3a3c20e759fe61d43be023b2caf3
https://doi.org/10.1182/blood.v57.6.1105.1105
https://doi.org/10.1182/blood.v57.6.1105.1105
Publikováno v:
Proceedings of the National Academy of Sciences. 77:1588-1592
A series of monoclonal antibodies was used to define three discrete stages of human intrathymic T-cell differentiation. The earliest stage was confined to + , OKT5 + , OKT6 + “common” thymocyte population represents the majority of thymocytes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0eb5489bdfe5dca0304f2589a9702df
https://doi.org/10.1073/pnas.77.3.1588
https://doi.org/10.1073/pnas.77.3.1588
Autor:
Michele Rhodes, Juliette M. Lefebvre, David L. Wiest, Gladys W. Wong, Juan Carlos Zúñiga-Pflücker, Jens Peter Holst Lauritsen, Maria Ciofani, Sang-Yun Lee, Dietmar J. Kappes
Publikováno v:
Immunity. (4):565-575
alphabeta and gammadelta T cells arise from a common thymocyte progenitor during development in the thymus. Emerging evidence suggests that the pre-T cell receptor (pre-TCR) and gammadelta T cell receptor (gammadeltaTCR) play instructional roles in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c95d873ea6566cc31c8565fa8ff2c32d
Publikováno v:
Cellular immunology. 89(1)
The reactivity of human cord blood lymphocytes was assessed against a panel of monoclonal antibodies (MoAb). The mean proportion of OKT3+ cells (pan-T) was significantly lower in cord blood (52 ± 13.8%; mean ± SD) compared with that of adult blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc69987084157ca11259e3207d8b42e
https://pubmed.ncbi.nlm.nih.gov/6386190
https://pubmed.ncbi.nlm.nih.gov/6386190