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pro vyhledávání: '"Common Thymocyte"'
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Publikováno v:
Thymus. 14(1-3)
The authors analysed 118 monoclonal antibodies in the Activation Antigen Section of the 4th International Workshop and Conference on Human Leucocyte Differentiation Antigens for their reactivity to thymus tissue sections. Nineteen samples gave a stro
Publikováno v:
Nature Reviews Immunology. 10:657-663
The thymus produces several types of functionally distinct T cell subsets. However, at a more fundamental level only two genetically distinct T cell lineages exist: the γδ and αß T cell lineages. Precisely how these two T cell lineages are genera
Autor:
Ali Lahjouji, Mohamed Khattab, Fatima Bachir, Mhamed Harif, Siham Cherkaoui, Rajae El Aouad, Ilham Nassereddine, Saadia Zafad, Sanae Bennani
Publikováno v:
International Journal of Pediatrics, Vol 2009 (2009)
International Journal of Pediatrics
International Journal of Pediatrics
We present the incidence and the immunologic characteristics of acute lymphoblastic leukemia (ALL) subsets in Moroccan children. We studied 279 unselected patients below the age of 18 years with newly diagnosed ALL. Cases were classified according to
Autor:
Jonathan Kaye, Parinaz Aliahmad
Publikováno v:
The Journal of Experimental Medicine
CD8+ cytotoxic and CD4+ helper/inducer T cells develop from common thymocyte precursors that express both CD4 and CD8 molecules. Upon T cell receptor signaling, these cells initiate a differentiation program that includes complex changes in CD4 and C
Autor:
Caterina Casadio, U. Massazza, Luca Durelli, M. F. Ferrio, R. Cavallo, Giuliano Maggi, L. Bergamini, G. Poccardi, M. Di Summa
Publikováno v:
Annals of Neurology. 27:174-180
Thymocytes express multiple, different surface antigens according to their stage of maturation. Surface differentiation antigens have been studied with the technique of simultaneous dual-color, direct immunofluorescence in the thymuses of 20 patients
Autor:
Ingrid Schmid, Christel H. Uittenbogaart, Loran T. Clement, Thomas C. Boone, Leanne W. Vollger, Sumihiko Higashitani
Publikováno v:
International Immunology. 2:1179-1187
Interleukin-4 (IL-4) is a multifunctional lymphokine which promotes the growth and/or maturation of multiple cell types. We have examined the ability of IL-4 to promote the phenotypic maturation of subsets of human thymocytes. When cultured in serum-
Publikováno v:
Blood. 97(1)
The organization and expression of the BCL-6 gene in normal and neoplastic thymic T cells has not been fully determined. We examined 8 precursor T-cell lymphoblastic lymphomas (T-LBLs) and found significant BCL-6 expression in 4 cases. Three of the B
Autor:
Khurana, Sharad1, Heckman, Michael G.2, Craig, Fiona E.3, Cochuyt, Jordan J.2, Greipp, Patricia4, Rahman, Zaid Abdel5, Sproat, Lisa Z.6, Litzow, Mark7, Foran, James M.8 Foran.James@mayo.edu, Liuyan (Jennifer) Jiang9
Publikováno v:
Archives of Pathology & Laboratory Medicine. Apr2024, Vol. 148 Issue 4, p471-475. 5p.
Publikováno v:
Proceedings of the National Academy of Sciences. 77:1588-1592
A series of monoclonal antibodies was used to define three discrete stages of human intrathymic T-cell differentiation. The earliest stage was confined to + , OKT5 + , OKT6 + “common” thymocyte population represents the majority of thymocytes and