Evolution, Expansion, and Functional Divergence of the Commissureless Protein Family

Autor: Glasbrenner, David C., Jr

During development of the Drosophila melanogaster embryonic central nervous system (CNS) many axons must cross the midline in the ventral nerve cord, analogous to the spinal cord in vertebrates, to reach their final target. Crossing the midline is hi

Externí odkaz: http://rave.ohiolink.edu/etdc/view?acc_num=osu1557143164958451

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Regulation of Slit-Robo Signaling by Commissureless and Comm Family Members

Autor: Carver, Laura

The field of axon guidance is concerned with deciphering how axons use temporal and spatial cues to pattern a precise trajectory. We use the fruit fly Drosophila melanogaster to study embryonic pathway decisions that are fundamental in connecting the

Externí odkaz: http://rave.ohiolink.edu/etdc/view?acc_num=osu1316455618

Function of commissureless and related genes in drosophila neural development

Autor: Choi, Yong-Jin

Commissureless (Comm) and Roundabout (Robo) are key regulators of axon guidance at the Drosophila CNS midline. Robo encodes a receptor for the midline repellent Slit and prevents ipsilaterally projecting axons from crossing the midline. Comm encodes

Externí odkaz: http://rave.ohiolink.edu/etdc/view?acc_num=osu1054558823

Ectopic expression in the giant fiber system of Drosophila reveals distinct roles for roundabout (Robo), Robo2, and Robo3 in dendritic guidance and synaptic connectivity

Autor: Tanja Godenschwege, Simpson, Jh, Shan, Xl, Bashaw, Gj, Goodman, Cs, Murphey, Rk

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 22, iss 8
Scopus-Elsevier
ResearcherID
Godenschwege, Tanja A; Simpson, Julie H; Shan, Xiaoliang; Bashaw, Greg J; Goodman, Corey S; & Murphey, Rodney K. (2002). Ectopic expression in the giant fiber system of Drosophila reveals distinct roles for roundabout (Robo), Robo2, and Robo3 in dendritic guidance and synaptic connectivity.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 22(8), 3117-3129. doi: 10.1523/jneurosci.22-08-03117.2002. UC Santa Barbara: Retrieved from: http://www.escholarship.org/uc/item/23p4k5v4

The Roundabout (Robo) receptors have been intensively studied for their role in regulating axon guidance in the embryonic nervous system, whereas a role in dendritic guidance has not been explored. In the adult giant fiber system of Drosophila, we ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2d26540564f61bf13679a2f27caabc84
https://escholarship.org/uc/item/23p4k5v4