Zobrazeno 1 - 10
of 83 813
pro vyhledávání: '"Combination therapy"'
Autor:
Aydin Eresen, Zigeng Zhang, Guangbo Yu, Qiaoming Hou, Zhilin Chen, Zeyang Yu, Vahid Yaghmai, Zhuoli Zhang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Heterogeneity of hepatocellular carcinoma (HCC) presents significant challenges for therapeutic strategies and necessitates combinatorial treatment approaches to counteract suppressive behavior of tumor microenvironment and achiev
Externí odkaz:
https://doaj.org/article/950fad8b8af9492ba6da0a8ed1a941cb
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background In the management of complex diseases, the strategic adoption of combination therapy has gained considerable prominence. Combination therapy not only holds the potential to enhance treatment efficacy but also to alleviate the side
Externí odkaz:
https://doaj.org/article/26107429a29644eda96bfd7766c9aaef
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The emergence of programmed death-1 (PD-1) and programmed death ligand 1 (PD-L1) immunosuppressants provides new therapeutic directions for various advanced malignant cancers. At present, PD-1/PD-L1 immunosuppressants have made significant p
Externí odkaz:
https://doaj.org/article/402b708099bb4ad8833bd0a3a3cfb273
Publikováno v:
Current Oncology, Vol 31, Iss 9, Pp 5412-5421 (2024)
Patients with advanced-stage mycosis fungoides (MF IIB–IVB) and Sézary syndrome (SS) have poor prognoses, with survival ranging from 4.7 to 1.4 years depending on the disease stage. There is a need for therapeutic approaches that lead to long-last
Externí odkaz:
https://doaj.org/article/3898995f466c441c99031f9d4b5c5169
Autor:
Shima Hasani, Mohammad Khalaj-Kondori, Sahar Safaei, Mohammad Amini, Negin Riazi-Tabrizi, Mohadeseh Maghsoudi, Behzad Baradaran
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Gastric cancer (GC) is a highly chemoresistant malignancy with a poor prognosis. Paclitaxel’s low response rate as second-line chemotherapy for advanced GC has prompted intensive research into its molecular basis and prospective
Externí odkaz:
https://doaj.org/article/ba01d739403343a9ba23d91f293e5ba4
Autor:
Fatemeh Nasiri, Yasaman Asaadi, Farzaneh Mirzadeh, Shahrokh Abdolahi, Sedigheh Molaei, Somayeh Piri Gavgani, Fatemeh Rahbarizadeh
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-31 (2024)
Abstract Multiple myeloma (MM) is a hematological cancer characterized by the abnormal proliferation of plasma cells. Initial treatments often include immunomodulatory drugs (IMiDs), proteasome inhibitors (PIs), and monoclonal antibodies (mAbs). Desp
Externí odkaz:
https://doaj.org/article/6b0a7e5a21414a61a1cddb7dba91e414
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4102-4117 (2024)
Tumor vaccine, a promising modality of tumor immunotherapy, needs to go through the process of tumor antigen generation and loading, antigen drainage to lymph nodes (LNs), antigen internalization by dendritic cells (DCs), DC maturation, and antigen c
Externí odkaz:
https://doaj.org/article/61bcdf2b95ba4d0aa73d5c9f523d4fc0
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-26 (2024)
Abstract Programmed death receptor-1 (PD-1) and its ligand, programmed death ligand-1 (PD-L1) are essential molecules that are key in modulating immune responses. PD-L1 is constitutively expressed on various immune cells, epithelial cells, and cancer
Externí odkaz:
https://doaj.org/article/f80a975a4b1745f3837cdb68c73e828a
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-15 (2024)
Abstract Soft tissue sarcomas (STS) have long been a formidable challenge in oncology, partly because of their rarity and diversity, which complicates large-scale studies and slows the advent of new treatments. Traditionally anchored by anthracycline
Externí odkaz:
https://doaj.org/article/7ef21262418c46b9b7f1ab1e7ac20ce2
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 9227-9253 (2024)
Guoqiang Xu,1,2,* Xiaona Song,2,* Xiaotang Wang,1,2,* Rui Xue,1,2 Xiaoru Yan,1,2 Litao Qin,1,2 Xiaoqi Chang,1,2 Jiping Gao,1 Zhaoyang Chen,1 Guohua Song1 1Laboratory Animal Center Shanxi Key Laboratory of Experimental Animal Science and H
Externí odkaz:
https://doaj.org/article/8e03627a33cc4ffb8aa300eb947ad717