Combining cell therapy with human autologous Schwann cell and bone marrow-derived mesenchymal stem cell in patients with subacute complete spinal cord injury: safety considerations and possible outcomes

Autor: Saeed Oraee-Yazdani, Mohammadhosein Akhlaghpasand, Maryam Golmohammadi, Maryam Hafizi, Mina Soufi Zomorrod, Nima Mohseni Kabir, Maryam Oraee-Yazdani, Farzad Ashrafi, Alireza Zali, Masoud Soleimani

Publikováno v: Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2021)

Abstract Background Cellular transplantations have promising effects on treating spinal cord injury (SCI) patients. Mesenchymal stem cells (MSCs) and Schwann cells (SCs), which have safety alongside their complementary characteristics, are suggested

Externí odkaz: https://doaj.org/article/17e37cc9f48d46a2ba154c84b0a19c62

Mesenchymal Stem Cells and Induced Bone Marrow‐Derived Macrophages Synergistically Improve Liver Fibrosis in Mice

Autor: Junichi Kikuta, Yuichi Kojima, Satoshi Seino, Yusuke Watanabe, Masaru Ishii, Hirokazu Kawai, Shuji Terai, Shunzo Ikarashi, Atsunori Tsuchiya, Satoshi Yamagiwa, Philip J. Starkey Lewis, Yuzo Kawata, Wei-Yu Lu, Stuart J. Forbes

Publikováno v: Stem Cells Translational Medicine
Watanabe, Y, Tsuchiya, A, Seino, S, Kawata, Y, Kojima, Y, Ikarashi, S, Starkey Lewis, P J, Lu, W-Y, Kikuta, J, Kawai, H, Yamagiwa, S, Forbes, S J, Ishii, M & Terai, S 2019, ' Mesenchymal Stem Cells and Induced Bone Marrow-Derived Macrophages Synergistically Improve Liver Fibrosis in Mice ', Stem Cells Translational Medicine, vol. 8, no. 3, pp. 271-284 . https://doi.org/10.1002/sctm.18-0105

We describe a novel therapeutic approach for cirrhosis using mesenchymal stem cells (MSCs) and colony-stimulating factor-1-induced bone marrow-derived macrophages (id-BMMs) and analyze the mechanisms underlying fibrosis improvement and regeneration.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977dc2fc2e5c29f1065d3f92645f30aa
http://europepmc.org/articles/PMC6392382

Translational aspects of cardiac cell therapy

Autor: Cheng-Han Chen, Benjamin M. Wu, Konstantina-Ioanna Sereti, Reza Ardehali

Publikováno v: Journal of Cellular and Molecular Medicine
Journal of cellular and molecular medicine, vol 19, iss 8

Cell therapy has been intensely studied for over a decade as a potential treatment for ischaemic heart disease. While initial trials using skeletal myoblasts, bone marrow cells and peripheral blood stem cells showed promise in improving cardiac funct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7952bb64eff2d84e9255c558b0803ee8
http://europepmc.org/articles/PMC4549027

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