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Akademický článek

A Genome-Wide CRISPR Interference Screen Reveals an StkP-Mediated Connection between Cell Wall Integrity and Competence in Streptococcus salivarius

Autor: Adrien Knoops, Alexandra Waegemans, Morgane Lamontagne, Baptiste Decat, Johann Mignolet, Jan-Willem Veening, Pascal Hols

Publikováno v: mSystems, Vol 7, Iss 6 (2022)

ABSTRACT Competence is one of the most efficient bacterial evolutionary and adaptative strategies by synchronizing production of antibacterial compounds and integration of DNA released by dead cells. In most streptococci, this tactic is orchestrated

Externí odkaz: https://doaj.org/article/71bc89fd27394731b51fa62201d7fefe

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Akademický článek

The CovRS Environmental Sensor Directly Controls the ComRS Signaling System To Orchestrate Competence Bimodality in Salivarius Streptococci

Autor: Adrien Knoops, Florence Vande Capelle, Laetitia Fontaine, Marie Verhaegen, Johann Mignolet, Philippe Goffin, Jacques Mahillon, Andrea Sass, Tom Coenye, Laura Ledesma-García, Pascal Hols

Publikováno v: mBio, Vol 13, Iss 1 (2022)

ABSTRACT In bacteria, phenotypic heterogeneity in an isogenic population compensates for the lack of genetic diversity and allows concomitant multiple survival strategies when choosing only one is too risky. This powerful tactic is exploited for comp

Externí odkaz: https://doaj.org/article/c50280d22ac54dd69aac2477362fd783

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A Genome-Wide CRISPR Interference Screen Reveals an StkPMediated Connection between Cell Wall Integrity and Competence in Streptococcus salivarius

Autor: Adrien Knoops, Alexandra Waegemans, Morgane Lamontagne, Baptiste Decat, Johann Mignolet, Jan-Willem Veening, Pascal Hols

Publikováno v: mSystems, Vol. 7, no.6, p. e0073522 (2022)
mSystems, vol. 7, no. 6, pp. e0073522

Competence is one of the most efficient bacterial evolutionary and adaptative strategies by synchronizing production of antibacterial compounds and integration of DNA released by dead cells. In most streptococci, this tactic is orchestrated by the Co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d773dd3acbff59df2bb093a4ce014ec2
https://zenodo.org/record/8030057

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Akademický článek

Transcriptional Profiling of the Oral Pathogen Streptococcus mutans in Response to Competence Signaling Peptide XIP

Autor: Iwona B. Wenderska, Andrew Latos, Benjamin Pruitt, Sara Palmer, Grace Spatafora, Dilani B. Senadheera, Dennis G. Cvitkovitch

Publikováno v: mSystems, Vol 2, Iss 1 (2017)

ABSTRACT In the cariogenic Streptococcus mutans, competence development is regulated by the ComRS signaling system comprised of the ComR regulator and the ComS prepeptide to the competence signaling peptide XIP (ComX-inducing peptide). Aside from com

Externí odkaz: https://doaj.org/article/23e1c7c0695146cdb0914218a4aab703

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Akademický článek

GROWTH OF STREPTOCOCCUS MUTANS IN BIOFILMS ALTERS PEPTIDE SIGNALING AT THE SUB-POPULATION LEVEL

Autor: Robert Colquhoun Shields, Robert Burne

Publikováno v: Frontiers in Microbiology, Vol 7 (2016)

Streptococcus mutans activates multiple cellular processes in response to the formation of a complex between comX-inducing peptide (XIP) and the ComR transcriptional regulator. Bulk phase and microfluidic experiments previously revealed that ComR-dep

Externí odkaz: https://doaj.org/article/4b72695e6dfb4bef8b976dff29f7c34a

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Dynamics of natural competence in Streptococcus salivarius

Autor: Knoops, Adrien

Competence is one of the most successful survival strategies in bacteria. This powerful tactic synchronizes the production of antimicrobial compounds which eliminates competitors, providing genomic material availability for subsequent DNA uptake. Yet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1493::83e9dc8376d748ca5315fe14c8b41ede
https://hdl.handle.net/2078.1/258238

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Akademický článek

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Molecular mechanism of quorum sensing inhibition in Streptococcus by the phage protein paratox

Autor: Gerd Prehna, Trushar R. Patel, Mazdak Khajehpour, Nicole R. Rutbeek, Hanieh Rezasoltani

Publikováno v: The Journal of Biological Chemistry

Streptococcus pyogenes, or Group A Streptococcus, is a Gram-positive bacterium that can be both a human commensal and pathogen. Central to this dichotomy are temperate bacteriophages that incorporate into the bacterial genome as a prophage. These gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f245894bfe754daaa46f6701a2cc034f
https://doi.org/10.1101/2021.06.03.446943

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Akademický článek

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