Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Colyn Crane Robinson"'
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
The UBTF E210K neuroregression syndrome is a predominantly neurological disorder caused by recurrent de novo dominant variants in Upstream Binding Factor, that is, essential for transcription of the ribosomal RNA genes. This unusual form of ribosomop
Externí odkaz:
https://doaj.org/article/907e0244128346188be93e78b3b585b4
Autor:
Colyn Crane-Robinson
Publikováno v:
Crystals, Vol 12, Iss 6, p 818 (2022)
DNA in the cell is rarely naked but normally protein-bound in nucleosomes. Of special interest is the DNA bound to other factors that control its key functions of transcription, replication, and repair. For these several transactions of DNA, the stat
Externí odkaz:
https://doaj.org/article/88717aa598224d62a8e2114a1ae441b9
Publikováno v:
The Biochemist. 45:31-32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e2d3b047a5d162ead280277eb717cc3
https://doi.org/10.1042/bio_2022_126
https://doi.org/10.1042/bio_2022_126
Autor:
Colyn Crane-Robinson, Peter Privalov
Publikováno v:
European biophysics journal : EBJ. 51(6)
The thermodynamic forces driving the formation of H-bonds in macromolecules have long been the subject of speculation, theory and experiment. Comparison of the energetic parameters of AT and GC base pairs in DNA duplexes has recently led to the reali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a527b92d9342951610805bc01fc1e1
https://pubmed.ncbi.nlm.nih.gov/35962202
https://pubmed.ncbi.nlm.nih.gov/35962202
Autor:
Colyn Crane-Robinson
Publikováno v:
Acta Naturae
Crane-Robinson, C 2021, ' Forces for folding ', Acta Naturae, vol. 13, no. 2, pp. 126-128 . < http://actanaturae.ru/2075-8251/issue/archive >
Crane-Robinson, C 2021, ' Forces for folding ', Acta Naturae, vol. 13, no. 2, pp. 126-128 . < http://actanaturae.ru/2075-8251/issue/archive >
Understanding the nature of the forces driving the folding of proteins, nucleic acids and the formation of their complexes absolutely requires thermodynamic data, in addition to structural information. In practical terms, this means the use of super-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a957a466eae7a241fc0bba2296c8a2
https://doi.org/10.32607/actanaturae.11336
https://doi.org/10.32607/actanaturae.11336
Publikováno v:
Privalov, P L & Crane-robinson, C 2020, ' Forces maintaining the DNA double helix ', European Biophysics Journal . https://doi.org/10.1007/s00249-020-01437-w
European Biophysics Journal
European Biophysics Journal
Despite the common acceptance that the enthalpy of DNA duplex unfolding does not depend on temperature and is greater for the CG base pair held by three hydrogen bonds than for the AT base pair held by only two, direct calorimetric measurements have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867315005b87c69c0c2edd7ae099b79a
https://doi.org/10.1007/s00249-020-01437-w
https://doi.org/10.1007/s00249-020-01437-w
Autor:
Anais Wanet, Mee Rie Sheen, Colyn Crane Robinson, Simone Ummarino, Daniel G. Tenen, Danielle Tenen, Vladimir Espinosa Angarica, Emanuele Monteleone, Valeria Poli, Annalisa Di Ruscio, Touati Benoukraf, Alexander K. Ebralidze, Rory Coffey, Mahmoud A. Bassal, Yanjing Liu, Bogdan Budnik, Haoran Zhang, Roberto Tirado Magallanes, Bon Q. Trinh, Yanzhou Zhang, Dennis Kappei
The mechanisms by which epigenetic modifications are established in gene regulatory regions of active genes remain poorly understood. The data presented show that the establishment and recycling of a major epigenetic mark, the acetylated form of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1af549d22709d0581c94d37ed16f9c5
https://doi.org/10.1101/2021.10.27.466094
https://doi.org/10.1101/2021.10.27.466094
Publikováno v:
European Biophysics Journal
Crane-Robinson, C, Read, C & Dragan, A 2018, ' Hydration differences between the major and minor grooves of DNA revealed from heat capacity measurements ', European Biophysics Journal . https://doi.org/10.1007/s00249-018-1340-0
Crane-Robinson, C, Read, C & Dragan, A 2018, ' Hydration differences between the major and minor grooves of DNA revealed from heat capacity measurements ', European Biophysics Journal . https://doi.org/10.1007/s00249-018-1340-0
The nature of water on the surface of a macromolecule is reflected in the temperature dependence of the heat effect, i.e., the heat capacity change, ΔCp, that accompanies its removal on forming a complex. The relationship between ΔCp and the nature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc49818134fb8384723fd9b90ee5a05
https://doi.org/10.1007/s00249-018-1340-0
https://doi.org/10.1007/s00249-018-1340-0
Publikováno v:
Dragan, A, Crane-Robinson, C & Privalov, P L 2021, ' Thermodynamic basis of the α-helix and DNA duplex ', European Biophysics Journal, vol. 50, no. 5, 252, pp. 787-792 . https://doi.org/10.1007/s00249-021-01520-w
European Biophysics Journal
European Biophysics Journal
Analysis of calorimetric and crystallographic information shows that the α-helix is maintained not only by the hydrogen bonds between its polar peptide groups, as originally supposed, but also by van der Waals interactions between tightly packed apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8399c16d6f3cd0f5f8aa766dae7fd5b1
https://doi.org/10.1007/s00249-021-01520-w
https://doi.org/10.1007/s00249-021-01520-w
Publikováno v:
Dragan, A, Privalov, P & Crane-Robinson, C 2019, ' Thermodynamics of DNA: heat capacity changes on duplex unfolding ', European Biophysics Journal, vol. 48, no. 8, pp. 773-779 . https://doi.org/10.1007/s00249-019-01403-1
European Biophysics Journal
European Biophysics Journal
The heat capacity change, ΔCp, accompanying the folding/unfolding of macromolecules reflects their changing state of hydration. Thermal denaturation of the DNA duplex is characterized by an increase in ΔCp but of much lower magnitude than observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c688fff19dbda32349ad98d1cdb9f0e
https://researchportal.port.ac.uk/ws/files/16476628/Thermodynamics_of_DNA.pdf
https://researchportal.port.ac.uk/ws/files/16476628/Thermodynamics_of_DNA.pdf