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Anti-Inflammatory Effect of Columbianadin against D-Galactose-Induced Liver Injury In Vivo via the JAK2/STAT3 and JAK2/p38/NF-κB Pathways.

Autor: Ma, Zhe^1,2 (AUTHOR) tzcmz@tzc.edu.cn, Peng, Lin^1,2 (AUTHOR) leogard2005@163.com, Sheng, Yaoyao¹ (AUTHOR) shengyaoyao0902@163.com, Chu, Wenhui^1,2 (AUTHOR) jake-chu@hotmail.com, Fu, Yongqian^1,2 (AUTHOR) jake-chu@hotmail.com

Publikováno v: Pharmaceuticals (14248247). Mar2024, Vol. 17 Issue 3, p378. 14p.

Columbianadin Ameliorates Myocardial Injury by Inhibiting Autophagy Through the PI3K/Akt/mTOR Signaling Pathway in AMI Mice and Hypoxic H9c2 Cells.

Autor: Zi-Chang N; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulea, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China.; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China., Ran A; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulea, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China., Hui-Hui S; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulea, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China., Qi J; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulea, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China., Jun-Li S; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulea, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China., Yan-Xu C; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulea, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China., Yu-Hong L; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulea, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China., Shu-Fei F; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulea, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China.; Shcool of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China., Hao-Ping M; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulea, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China.

Publikováno v: Phytotherapy research : PTR [Phytother Res] 2024 Nov 21. Date of Electronic Publication: 2024 Nov 21.

S6K/FLNC/ITGβ3 signaling pathway regulates osteoclastogenesis and the inhibition of osteoclastogenesis by columbianadin.

Autor: Wei Q; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, PR China; State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, PR China., Niu ZC; The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, PR China., Fu XY; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, PR China; State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, PR China., OuYang MH; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, PR China; State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, PR China., Guo XT; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, PR China; State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, PR China., Li J; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, PR China; State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, PR China., Chang YX; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, PR China. Electronic address: Tcmcyx@tjutcm.edu.cn., Mao HP; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, PR China; State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, PR China. Electronic address: maohaoping@tjutcm.edu.cn., Gao XM; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, PR China; State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, PR China. Electronic address: gaoxiumei@tjutcm.edu.cn.

Publikováno v: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Nov 23; Vol. 136, pp. 156276. Date of Electronic Publication: 2024 Nov 23.

Columbianadin ameliorates experimental acute reflux esophagitis in rats via suppression of NF-κB pathway

Autor: Ying Wu, Shaik Althaf Hussain, Minghai Luo

Publikováno v: Acta Cirúrgica Brasileira, Vol 39 (2024)

ABSTRACT Purpose: Reflux esophagitis is a condition characterized by inflammation and irritation of the esophagus, resulting from the backflow of stomach acid and other gastric contents into the esophagus. Columbianadin is a coumarin derivative that

Externí odkaz: https://doaj.org/article/da7a4d735a9d4439b1d1c1b2ec656227