Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Colton J. Bracken"'
Autor:
Shion A. Lim, Josef A. Gramespacher, Katarina Pance, Nicholas J. Rettko, Paige Solomon, Jing Jin, Irene Lui, Susanna K. Elledge, Jia Liu, Colton J. Bracken, Graham Simmons, Xin X. Zhou, Kevin K. Leung, James A. Wells
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Numerous neutralizing antibodies that target SARS-CoV-2 have been reported, and most directly block binding of the viral Spike receptor-binding domain (RBD) to angiotensin-converting enzyme II (ACE2). Here, we deliberately exploit non-neutralizing RB
Externí odkaz:
https://doaj.org/article/58387a18a15c49f9b2ec691ffba6d02b
Autor:
Alexander J. Martinko, Erin F. Simonds, Suchitra Prasad, Alberto Ponce, Colton J. Bracken, Junnian Wei, Yung-Hua Wang, Tiffany-Lynn Chow, Zhong Huang, Michael J. Evans, James A. Wells, Zachary B. Hill
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The antigen specificity and long serum half-life of monoclonal antibodies have made them a critical part of modern therapeutics. These properties have been coopted in a number of synthetic formats, such as antibody-drug conjugates, bispecific antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a6ed10a79114365899c2f9172d7d10
https://doi.org/10.1073/pnas.2117402119
https://doi.org/10.1073/pnas.2117402119
Autor:
Graham Simmons, Josef A. Gramespacher, Irene Lui, Shion A. Lim, Colton J Bracken, Jing Jin, Kevin Leung, Xin X. Zhou, Jia Liu, Paige Solomon, James A. Wells, Susanna K. Elledge, Nicholas J. Rettko, Katarina Pance
Publikováno v:
mAbs
article-version (VoR) Version of Record
mAbs, vol 13, iss 1
article-version (VoR) Version of Record
mAbs, vol 13, iss 1
Numerous neutralizing antibodies that target SARS-CoV-2 have been reported, and most directly block binding of the viral Spike receptor-binding domain (RBD) to angiotensin-converting enzyme II (ACE2). Here, we deliberately exploit non-neutralizing RB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8959f3f68f7b3aeb9f632d43f7a03e59
http://europepmc.org/articles/PMC7939556
http://europepmc.org/articles/PMC7939556
Autor:
Jie Zhou, Nicholas J. Rettko, Katarina Pance, Beth S. Zha, Irene Lui, Jia Liu, Duy P. Nguyen, James Byrnes, Kevin Leung, James A. Wells, Paige Solomon, Kaitlin Schaefer, Shion A. Lim, Colton J Bracken, Xin X. Zhou
Publikováno v:
Nature Chemical Biology
Nature chemical biology, vol 17, iss 1
Nature chemical biology, vol 17, iss 1
Neutralizing agents against SARS-CoV-2 are urgently needed for the treatment and prophylaxis of COVID-19. Here, we present a strategy to rapidly identify and assemble synthetic human variable heavy (VH) domains toward neutralizing epitopes. We constr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ce62903260b5e9c9b72443b6c966b9
Autor:
Paige Solomon, Beth S. Zha, Jia Liu, James A. Wells, Katarina Pance, James Byrnes, Jie Zhou, Kevin Leung, Xin X. Zhou, Kaitlin Schaefer, Duy P. Nguyen, Nicholas J. Rettko, Irene Lui, Shion A. Lim, Colton J Bracken
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
Nature chemical biology
article-version (status) pre
article-version (number) 1
Nature chemical biology
Neutralizing agents against SARS-CoV-2 are urgently needed for treatment and prophylaxis of COVID-19. Here, we present a strategy to rapidly identify and assemble synthetic human variable heavy (VH) domain binders with high affinity toward neutralizi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e42a6899aff9c7d8f74d97b0876d29c6
http://europepmc.org/articles/PMC7430580
http://europepmc.org/articles/PMC7430580