Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Colton D. Payne"'
Autor:
Dan Wang, Volker Herzig, Zoltan Dekan, K. Johan Rosengren, Colton D. Payne, Md. Mahadhi Hasan, Jiajie Zhuang, Emmanuel Bourinet, Lotten Ragnarsson, Paul F. Alewood, Richard J. Lewis
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4745 (2024)
Venom peptides have evolved to target a wide range of membrane proteins through diverse mechanisms of action and structures, providing promising therapeutic leads for diseases, including pain, epilepsy, and cancer, as well as unique probes of ion cha
Externí odkaz:
https://doaj.org/article/360f44695aa442f990f1e14e2c340589
Autor:
Cedric S. Cui, Richard J. Clark, Xaria X. Li, Declan M. Gorman, Trent M. Woodruff, John D. Lee, Colton D. Payne, K. Johan Rosengren
Publikováno v:
ACS Pharmacology & Translational Science. 4:1808-1817
Publikováno v:
Journal of Natural Products. 84:2914-2922
Plants are an excellent source of bioactive peptides, often with disulfide bonds and/or a cyclic backbone. While focus has predominantly been directed at disulfide-rich peptides, a large family of small, cyclic but non-disulfide bonded peptides known
Autor:
Angela Song, Mark F. Fisher, Jingjing Zhang, Carl Eliasson, Courtney E. McAleese, Grishma Vadlamani, Colton D. Payne, Fatemeh Hajiaghaalipour, Achala S. Jayasena, Richard J. Clark, Bastian Franke, K. Johan Rosengren, Rodney F. Minchin, Joshua S. Mylne
Publikováno v:
Chemical Science
Head-to-tail cyclized peptides are intriguing natural products with unusual properties. The PawS-Derived Peptides (PDPs) are ribosomally synthesized as part of precursors for seed storage albumins in species of the daisy family, and are post-translat
Publikováno v:
Amino Acids
The complement component C5 inhibitory peptide zilucoplan is currently in phase III clinical trials for myasthenia gravis (MG). Despite being at an advanced stage of clinical development, there have been no published reports in the literature detaili
Autor:
Joshua S. Mylne, Ulf Göransson, K. Johan Rosengren, Charles S. Bond, Håkan S. Andersson, Richard J. Clark, Fatemeh Hajiaghaalipour, Mark F. Fisher, Grishma Vadlamani, Colton D. Payne, Taj Muhammad
Publikováno v:
RSC Chemical Biology
Head-to-tail cyclic and disulfide-rich peptides are natural products with applications in drug design. Among these are the PawS-Derived Peptides (PDPs) produced in seeds of the daisy plant family. PDP-23 is a unique member of this class in that it is
Autor:
Karin, Steffen, Quentin, Laborde, Sunithi, Gunasekera, Colton D, Payne, K Johan, Rosengren, Ana, Riesgo, Ulf, Göransson, Paco, Cárdenas
Publikováno v:
Journal of Natural Products
Natural product discovery by isolation and structure elucidation is a laborious task often requiring ample quantities of biological starting material and frequently resulting in the rediscovery of previously known compounds. However, peptides are a c
Autor:
Declan M, Gorman, Xaria X, Li, Colton D, Payne, Cedric S, Cui, John D, Lee, K Johan, Rosengren, Trent M, Woodruff, Richard J, Clark
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] The complement activation peptide C5a is a key mediator of inflammation that is associated with numerous immune disorders. C5a binds and activates two seven-transmembrane receptors, C5aR1 and C5aR2. Experimentally, C5a is utilized t
Publikováno v:
Journal of Natural Products. 82:2152-2158
Cyclic peptides are abundant in plants and have attracted interest due to their bioactivity and potential as drug scaffolds. Orbitides are head-to-tail cyclic peptides that are ribosomally synthesized, post-translationally modified, and lack disulfid
Autor:
Karin Steffen, Quentin Laborde, Sunithi Gunasekera, Colton D. Payne, K. Johan Rosengren, Ana Riesgo, Ulf Göransson, Paco Cárdenas
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Natural product discovery by isolation and structure elucidation is a laborious task often requiring ample quantities of biological starting material and frequently resulting in the rediscovery of previously known compounds. However, peptides are a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea829bdf33094deafcbc755a5ea84f0
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-460789
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-460789