Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Colonic Neoplasms/*genetics/*pathology"'
Autor:
Jean-Luc Wolfender, Constant Anatole Pieme, Vladimir L. Katanaev, Tatiana V. Petrova, Artem Blagodatski, Emerson Ferreira Queiroz, Kamal Ahmed, Alexey Koval, Simone Ragusa
Publikováno v:
Cancer Letters, Vol. 435 (2018) pp. 110-120
Triple-negative breast cancer (TNBC) and colon cancer (CC) are two stigmatic examples of poorly treatable tumors, whose progression critically depends upon hyperactivation of the Wnt signaling. Development of specific anti-Wnt inhibitors is required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9ea4ca74943aba182086d35f7e52d09
https://doi.org/10.1016/j.canlet.2018.08.003
https://doi.org/10.1016/j.canlet.2018.08.003
Autor:
Thierry Levade, Jean-Charles Portais, Romain Riscal, Maud Heuillet, Madi Y. Cissé, Floriant Bellvert, Frédérique Sabourdy, Pierre Thibaut, Eric Bonneil, Emilie Schrepfer, Laurent Le Cam, Giuseppe Arena, Laetitia K. Linares, Jean-Emmanuel Sarry, Imade Ait-Arsa, Jean-Christophe Marine, Florian Rambow, Charles Vincent
Publikováno v:
Molecular Cell
Molecular Cell, 2016, 62 (6), pp.890-902. ⟨10.1016/j.molcel.2016.04.033⟩
Molecular Cell, Elsevier, 2016, 62 (6), pp.890-902. ⟨10.1016/j.molcel.2016.04.033⟩
Molecular Cell, 2016, 62 (6), pp.890-902. ⟨10.1016/j.molcel.2016.04.033⟩
Molecular Cell, Elsevier, 2016, 62 (6), pp.890-902. ⟨10.1016/j.molcel.2016.04.033⟩
The mouse double minute 2 (MDM2) oncoprotein is recognized as a major negative regulator of the p53 tumor suppressor, but growing evidence indicates that its oncogenic activities extend beyond p53. Here, we show that MDM2 is recruited to chromatin in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4544e00da2461a9c18041ad9492c37dd
https://hal.science/hal-01886397
https://hal.science/hal-01886397
Autor:
E. Julieta Smith, Katsumi Miyai, Pascal Gervaz, Robert S. Sandler, Temitope O. Keku, Barbara H. Jung, Ryan T. Doctolero, John M. Carethers, Julio C. Alonso
Publikováno v:
International Journal of Cancer, Vol. 118, No 10 (2006) pp. 2509-13
High-frequency microsatellite unstable (MSI-H) colon tumors develop as a consequence of mutations at repetitive sequences in target genes. TGFBR2 and ACVR2, encoding TGFb superfamily receptors, and the proapoptotic gene BAX are frequent targets for f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3191e247f0b499779eb26476d11f9d35