Targeting Integration to Selected Genomic Loci and In Situ Tailoring of Cassette Design Allows Robust Transgene Expression without Perturbing Endogenous Transcription

Autor: Lombardo A, Cesana D, Genovese P. Provasi E, Colombo DF, Neri M, Magnani Z, Cantore A, Lo Riso P, Damo M, Holmes4 MC, Gregory PD, Gritti A, Bonini C, Naldini L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10495::1fe42ce397375aea0e1c22874b5f3e4b

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Electrophysiological efficacy of temperature-controlled bipolar radiofrequency

Autor: Ottavio Alfieri, Maurizio Taramasso, Domenico Cianflone, Stefano Benussi, Francesco Ancona, Alberto Pozzoli, Daniele F Colombo, Paolo Della Bella

OBJECTIVE: Clinical success of atrial fibrillation (AF) ablation depends on persistent block of electrical conduction across the ablation lines. The fate of ablations performed with temperature-controlled bipolar radiofrequency (RF) is unknown. The p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222d8ed74041e38852f493441dd0404e
http://hdl.handle.net/11379/538618

Preclinical spheroid models identify BMX as a therapeutic target for metastatic MYCN nonamplified neuroblastoma.

Autor: Sundaramoorthy S; Experimental Pathology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Colombo DF; Infectious Diseases Biomarkers, Janssen Research and Development, Beerse, Belgium., Sanalkumar R; Experimental Pathology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Broye L; Experimental Pathology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Balmas Bourloud K; Department Woman-Mother-Child, Division of Pediatrics, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Boulay G; Department of Pathology and Cancer Center, Massachusetts General Hospital and Harvard Medical School., Cironi L; Experimental Pathology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Stamenkovic I; Experimental Pathology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Renella R; Department Woman-Mother-Child, Division of Pediatrics, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Kuttler F; Biomolecular Screening Facility, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland., Turcatti G; Biomolecular Screening Facility, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland., Rivera MN; Department of Pathology and Cancer Center, Massachusetts General Hospital and Harvard Medical School., Mühlethaler-Mottet A; Department Woman-Mother-Child, Division of Pediatrics, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Bardet AF; Biotechnology and Cell Signaling (BSC), CNRS UMR7242, University of Strasbourg, Illkirch, France.; Institute of Genetics and Molecular and Cellular Biology (IGBMC), CNRS UMR7104, University of Strasbourg, INSERM U1258, Illkirch, France., Riggi N; Experimental Pathology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Publikováno v: JCI insight [JCI Insight] 2024 Jul 22; Vol. 9 (14). Date of Electronic Publication: 2024 Jul 22.