Dress syndrome and fulminant hepatic failure induced by lamotrigine

Autor: Marcelo Fabián Amante, Analía Verónica Filippini, Nora Cejas, Javier Lendoire, Oscar Imventarza, Coloma Parisi

Publikováno v: Annals of Hepatology, Vol 8, Iss 1, Pp 75-77 (2009)

Lamotrigine is a non-aromatic antiepileptic drug. Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a severe idiosyncratic reaction to drugs, especially anti-epileptic drugs. Associated clinical features include cutaneous eruption

Externí odkaz: https://doaj.org/article/d4e3d115c2ed4d8b9259a75131de6ea0

A proteome-scale map of the SARS-CoV-2-human contactome.

Autor: Kim DK; Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Weller B; Institute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany., Lin CW; Institute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany., Sheykhkarimli D; Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA., Knapp JJ; Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA., Dugied G; Unité de Génétique Moléculaire des Virus à ARN, Département de Virologie, Institut Pasteur, Paris, France.; UMR3569, Centre National de la Recherche Scientifique, Paris, France.; Université de Paris, Paris, France., Zanzoni A; Aix-Marseille Université, Inserm, TAGC, Marseille, France., Pons C; Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute for Science and Technology, Barcelona, Spain., Tofaute MJ; Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany., Maseko SB; Laboratory of Viral Interactomes, GIGA Institute, University of Liège, Liège, Belgium., Spirohn K; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Laval F; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.; Laboratory of Viral Interactomes, GIGA Institute, University of Liège, Liège, Belgium.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; TERRA Teaching and Research Centre, University of Liège, Gembloux, Belgium.; Laboratory of Molecular and Cellular Epigenetics, GIGA Institute, University of Liège, Liège, Belgium., Lambourne L; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Kishore N; Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA., Rayhan A; Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA., Sauer M; Institute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany., Young V; Institute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany., Halder H; Institute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany., la Rosa NM; Institute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany., Pogoutse O; Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA., Strobel A; Institute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany., Schwehn P; Institute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany., Li R; Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA., Rothballer ST; Institute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany., Altmann M; Institute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany., Cassonnet P; Unité de Génétique Moléculaire des Virus à ARN, Département de Virologie, Institut Pasteur, Paris, France.; UMR3569, Centre National de la Recherche Scientifique, Paris, France.; Université de Paris, Paris, France., Coté AG; Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA., Vergara LE; Institute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany., Hazelwood I; Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA., Liu BB; Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA., Nguyen M; Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA., Pandiarajan R; Institute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany., Dohai B; Institute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany., Coloma PAR; Institute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany., Poirson J; Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Molecular Architecture of Life Program, Canadian Institute for Advanced Research (CIFAR), Toronto, ON, Canada., Giuliana P; Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA., Willems L; TERRA Teaching and Research Centre, University of Liège, Gembloux, Belgium.; Laboratory of Molecular and Cellular Epigenetics, GIGA Institute, University of Liège, Liège, Belgium., Taipale M; Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Laboratory of Viral Interactomes, GIGA Institute, University of Liège, Liège, Belgium., Jacob Y; Unité de Génétique Moléculaire des Virus à ARN, Département de Virologie, Institut Pasteur, Paris, France.; UMR3569, Centre National de la Recherche Scientifique, Paris, France.; Université de Paris, Paris, France., Hao T; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Hill DE; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Brun C; Aix-Marseille Université, Inserm, TAGC, Marseille, France.; CNRS, Marseille, France., Twizere JC; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.; Laboratory of Viral Interactomes, GIGA Institute, University of Liège, Liège, Belgium.; TERRA Teaching and Research Centre, University of Liège, Gembloux, Belgium., Krappmann D; Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany., Heinig M; Institute of Computational Biology (ICB), Computational Health Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany.; Department of Informatics, Technische Universität München, Munich, Germany., Falter C; Institute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany., Aloy P; Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute for Science and Technology, Barcelona, Spain.; Institució Catalana de Recerca I Estudis Avaçats (ICREA), Barcelona, Spain., Demeret C; Unité de Génétique Moléculaire des Virus à ARN, Département de Virologie, Institut Pasteur, Paris, France. caroline.demeret@pasteur.fr.; UMR3569, Centre National de la Recherche Scientifique, Paris, France. caroline.demeret@pasteur.fr.; Université de Paris, Paris, France. caroline.demeret@pasteur.fr., Vidal M; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA. marc_vidal@dfci.harvard.edu.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. marc_vidal@dfci.harvard.edu., Calderwood MA; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA. michael_calderwood@dfci.harvard.edu.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. michael_calderwood@dfci.harvard.edu.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA. michael_calderwood@dfci.harvard.edu., Roth FP; Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, Ontario, Canada. fritz.roth@utoronto.ca.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. fritz.roth@utoronto.ca.; Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada. fritz.roth@utoronto.ca.; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA. fritz.roth@utoronto.ca.; Department of Computer Science, University of Toronto, Toronto, Ontario, Canada. fritz.roth@utoronto.ca., Falter-Braun P; Institute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany. pascal.falter-braun@helmholtz-muenchen.de.; Microbe-Host Interactions, Faculty of Biology, Ludwig-Maximilians-Universität (LMU) München, Planegg-Martinsried, Germany. pascal.falter-braun@helmholtz-muenchen.de.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2023 Jan; Vol. 41 (1), pp. 140-149. Date of Electronic Publication: 2022 Oct 10.