Zobrazeno 1 - 10
of 39
pro vyhledávání: '"ColoPulse"'
Autor:
Annemarie Broesder, Said Y. Bircan, Anneko B. de Waard, Anko C. Eissens, Henderik W. Frijlink, Wouter L. J. Hinrichs
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 1985 (2021)
The ColoPulse coating is a pH-dependent coating that can be used to target drug release to the ileo-colonic region. ColoPulse coated tablets and capsules have demonstrated their targeting capabilities in vivo in more than 100 volunteers and patients.
Externí odkaz:
https://doaj.org/article/01611fb1590542a999a2294bcd6b4735
Autor:
Annemarie Broesder, Julia M. E. Berends, Sophie M. Scheepers, Duong N. Nguyen, Henderik W. Frijlink, Wouter L. J. Hinrichs
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 731 (2021)
Targeting celecoxib to the ileo-colonic region could be beneficial for the treatment and prevention of colon cancer. Ileo-colonic targeting can be achieved by using pH-dependent coating systems such as ColoPulse. Celecoxib has poor aqueous solubility
Externí odkaz:
https://doaj.org/article/ae1e84f9437344eba10707e6c245da64
Akademický článek
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Autor:
Khanh T. T. Nguyen, Franca F. M. Heijningen, Daan Zillen, Kjeld J. C. van Bommel, Renz J. van Ee, Henderik W. Frijlink, Wouter L. J. Hinrichs
Publikováno v:
Pharmaceutics; Volume 14; Issue 10; Pages: 2179
Pharmaceutics, 14(10):2179. MDPI AG
Pharmaceutics, 14(10):2179. MDPI AG
Powder bed printing is a 3D-printing process that creates freeform geometries from powders, with increasing traction for personalized medicine potential. Little is known about its applications for biopharmaceuticals. In this study, the production of
Autor:
Bahez Gareb, Silke Posthumus, Max Beugeling, Pauline Koopmans, Daan J. Touw, Gerard Dijkstra, Jos G.W. Kosterink, Henderik W. Frijlink
Publikováno v:
Pharmaceutics, Vol 11, Iss 9, p 428 (2019)
Infliximab (IFX) is an intravenously administered monoclonal antibody antagonizing the effects of tumor necrosis factor-alpha (TNF) systemically and is efficacious in the treatment of inflammatory bowel disease (IBD). However, studies suggest that th
Externí odkaz:
https://doaj.org/article/dc43760a73034ef4bbe5a143ce96ec1f
Autor:
Henderik W. Frijlink, Wouter L. J. Hinrichs, Annemarie Broesder, Said Y. Bircan, Anneko B. de Waard, Anko C. Eissens
Publikováno v:
Pharmaceutics; Volume 13; Issue 12; Pages: 1985
Pharmaceutics, 13(12):1985. MDPI AG
Pharmaceutics, Vol 13, Iss 1985, p 1985 (2021)
Pharmaceutics
Pharmaceutics, 13(12):1985. MDPI AG
Pharmaceutics, Vol 13, Iss 1985, p 1985 (2021)
Pharmaceutics
The ColoPulse coating is a pH-dependent coating that can be used to target drug release to the ileo-colonic region. ColoPulse coated tablets and capsules have demonstrated their targeting capabilities in vivo in more than 100 volunteers and patients.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Jos G. W. Kosterink, Antonius T. Otten, Gerard Dijkstra, Silke Posthumus, Bahez Gareb, Max Beugeling, Henderik W. Frijlink
Publikováno v:
Journal of drug delivery science and technology, 64:102552. Elsevier
Research shows that topically active infliximab therapy may be efficacious in the treatment of inflammatory bowel disease (IBD) with expected fewer side effects related to systemic exposure. Oral administration of infliximab with site-specific delive
Autor:
Duong N Nguyen, Sophie M Scheepers, Henderik W. Frijlink, Wouter L. J. Hinrichs, Annemarie Broesder, Julia M E Berends
Publikováno v:
Pharmaceutics, Vol 13, Iss 731, p 731 (2021)
Pharmaceutics, 13(5). MDPI AG
Pharmaceutics
Volume 13
Issue 5
Pharmaceutics, 13(5). MDPI AG
Pharmaceutics
Volume 13
Issue 5
Targeting celecoxib to the ileo-colonic region could be beneficial for the treatment and prevention of colon cancer. Ileo-colonic targeting can be achieved by using pH-dependent coating systems such as ColoPulse. Celecoxib has poor aqueous solubility
Publikováno v:
International Journal of Pharmaceutics, 554, 366-375. Elsevier Bedrijfsinformatie b.v.
Up to 50% of Crohn's disease and ulcerative colitis patients suffer from ileo-colonic inflammation. Topically delivered budesonide is an effective treatment but in vitro as well as clinical data suggest that oral formulations currently used in clinic