CD44-high neural crest stem-like cells are associated with tumour aggressiveness and poor survival in neuroblastoma tumours

Autor: Francisco M. Vega, Ana Colmenero-Repiso, María A. Gómez-Muñoz, Ismael Rodríguez-Prieto, Diana Aguilar-Morante, Gema Ramírez, Catalina Márquez, Rosa Cabello, Ricardo Pardal

Publikováno v: EBioMedicine, Vol 49, Iss , Pp 82-95 (2019)

Background: Neuroblastoma is a paediatric tumour originated from sympathoadrenal precursors and characterized by its heterogeneity and poor outcome in advanced stages. Intra-tumoral cellular heterogeneity has emerged as an important feature in neurob

Externí odkaz: https://doaj.org/article/b93ece0c075c42bbafdd3defd079033c

Response to 'High CD44 expression is not a prognosis marker in patients with high-risk neuroblastoma'

Autor: Francisco M. Vega, Ana Colmenero-Repiso, María A. Gómez-Muñoz, Ismael Rodríguez-Prieto, Diana Aguilar-Morante, Gema Ramírez, Catalina Márquez, Rosa Cabello, Ricardo Pardal

Publikováno v: EBioMedicine, Vol 53, Iss , Pp - (2020)

Externí odkaz: https://doaj.org/article/a70677f73aa84243ad6a268d155ce076

Analysis of Serial Neuroblastoma PDX Passages in Mice Allows the Identification of New Mediators of Neuroblastoma Aggressiveness

Autor: María A. Gómez-Muñoz, Diana Aguilar-Morante, Ana Colmenero-Repiso, Aida Amador-Álvarez, Mónica Ojeda-Puertas, Juan Antonio Cordero Varela, Ismael Rodríguez-Prieto, Ricardo Pardal, Francisco M. Vega

Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1590

Neuroblastoma is a neural crest cell-derived pediatric tumor characterized by high inter- and intra-tumor heterogeneity, and by a poor outcome in advanced stages. Patient-derived xenografts (PDXs) have been shown to be useful models for preserving an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66bfbd89d7802e9269f8634d224a159
http://hdl.handle.net/10261/309348

Papel de la quinasa humana VRK1 en la biología del neuroblastoma

Autor: Colmenero-Repiso, Ana

Publikováno v: idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC

Tesis doctoral.-- Universidad de Sevilla. Departamento de Fisiología Médica y Biofísica. Programa de Doctorado:Biología Molecular, Biomedicina e Investigación Clínica.
[ES] El neuroblastoma es el tumor extracraneal sólido más frecuente e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::33baf4b9a359e19aa177bd60a147b879

Neural crest derived progenitor cells contribute to tumor stroma and aggressiveness in stage 4/M neuroblastoma

Autor: Vicente Santa-Maria, Catalina Márquez, Ana Colmenero-Repiso, Rosa Cabello, Diana Aguilar-Morante, Pedro Linares-Clemente, Ismael Rodríguez-Prieto, Carmen de Torres, Francisco M. Vega, Eloy Rivas, Gema Ramírez, Diego Pascual-Vaca, Ricardo Pardal, Jaume Mora

Publikováno v: Oncotarget
Digital.CSIC. Repositorio Institucional del CSIC
instname

Pediatric tumors arise upon oncogenic transformation of stem/progenitor cells during embryonic development. Given this scenario, the existence of non-tumorigenic stem cells included within the aberrant tumoral niche, with a potential role in tumor bi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e22674457dceb38d1d2b42f12546929a
https://doi.org/10.18632/oncotarget.21128