Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Colman J Hatton"'
Autor:
Shaday Michan, Aimee M Juan, Christian G Hurst, Zhenghao Cui, Lucy P Evans, Colman J Hatton, Dorothy T Pei, Meihua Ju, David A Sinclair, Lois E H Smith, Jing Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85031 (2014)
Proliferative retinopathy is a leading cause of blindness, including retinopathy of prematurity (ROP) in children and diabetic retinopathy in adults. Retinopathy is characterized by an initial phase of vessel loss, leading to tissue ischemia and hypo
Externí odkaz:
https://doaj.org/article/9e52085956a84969910e9d7eead06e5e
Autor:
Jing Chen, Andreas Stahl, Nathan M Krah, Molly R Seaward, Jean-Sebastian Joyal, Aimee M Juan, Colman J Hatton, Christopher M Aderman, Roberta J Dennison, Keirnan L Willett, Przemyslaw Sapieha, Lois E H Smith
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30203 (2012)
Mutations in low-density lipoprotein receptor-related protein 5 (Lrp5) impair retinal angiogenesis in patients with familial exudative vitreoretinopathy (FEVR), a rare type of blinding vascular eye disease. The defective retinal vasculature phenotype
Externí odkaz:
https://doaj.org/article/b95b34056b594302b9b6d0fd3915b137
Autor:
Brit Long, Elliot D. Backer, Matthew A. Roginski, Colman J. Hatton, Skyler Lentz, Patricia Ruth A. Atchinson
Publikováno v:
The American Journal of Emergency Medicine. 50:148-155
Introduction Massive hemoptysis is a life-threatening emergency that requires rapid evaluation and management. Recognition of this deadly condition, knowledge of the initial resuscitation and diagnostic evaluation, and communication with consultants
Publikováno v:
Annals of Pharmacotherapy. :106002802311638
Background: Diabetic ketoacidosis (DKA) is a serious acute complication of both type 1 and type 2 diabetes that requires prompt management. Limited data exist supporting the use of a 2-bag DKA protocol in adult patients across all levels of care. Obj
Autor:
Zhenghao Cui, David A. Sinclair, Aimee M. Juan, Dorothy T. Pei, Jean-Sébastien Joyal, Lucy P. Evans, Christian G. Hurst, Lois E.H. Smith, Przemyslaw Sapieha, Andreas Stahl, Shaday Michan, Colman J. Hatton, Jing Chen
Publikováno v:
Angiogenesis. 16:985-992
Regeneration of blood vessels in ischemic neuronal tissue is critical to reduce tissue damage in diseases. In proliferative retinopathy, initial vessel loss leads to retinal ischemia, which can induce either regrowth of vessels to restore normal meta
Autor:
Elisa Boscolo, Nathan M. Krah, Aimee M. Juan, Dorothy T. Pei, Przemyslaw Sapieha, Christian G. Hurst, Molly R. Seaward, Emily R. Greene, Jean-Sebastian Joyal, Jing Chen, Dipak Panigrahy, Andreas Stahl, Lois E.H. Smith, Roberta J. Dennison, Colman J. Hatton
Publikováno v:
Blood. 120:2925-2929
Inflammatory cytokines and growth factors drive angiogenesis independently; however, their integrated role in pathologic and physiologic angiogenesis is not fully understood. Suppressor of cytokine signaling-3 (SOCS3) is an inducible negative feedbac
Autor:
Kerry A. Pierce, Clary B. Clish, Michael B. Powner, Lucy P. Evans, Marin L. Gantner, Alan B. Packard, Edith Aguilar, Jin Sung Kim, Zhuo Shao, Jing Chen, Zhongjie Fu, Samuel B. Burnim, Ye Sun, Bruno Maranda, Aimee M. Juan, Martin Friedlander, Przemyslaw Sapieha, Christian G. Hurst, Nicholas Saba, Emile Levy, Colman J. Hatton, Flavio A. Rezende, Thomas Fredrick, Gauri Patel, Marcus Fruttiger, Patrick Bherer, Lois E.H. Smith, Zhenghao Cui, Michel Boisvert, Kristis Vevis, Jean-Sébastien Joyal
Publikováno v:
Nature medicine
Tissues with high metabolic rates often use lipid as well as glucose for energy, conferring a survival advantage during feast and famine.1 Current dogma suggests that high-energy consuming photoreceptors depend on glucose.2,3 Here we show that retina
Autor:
Matthew Campbell, Roberta J. Dennison, Lois E.H. Smith, Aimee M. Juan, Akiko Mammoto, Jing Chen, Karen I. Guerin, C. M. Aderman, Keirnan L. Willett, Nathan M. Krah, Przemyslaw Sapieha, Colman J. Hatton, Jing Hua, Andreas Stahl, Molly R. Seaward
Publikováno v:
Circulation. 124:1871-1881
Background— Ischemic proliferative retinopathy, characterized by pathological retinal neovascularization, is a major cause of blindness in working-age adults and children. Defining the molecular pathways distinguishing pathological neovascularizati
Autor:
Andreas Stahl, Darryl C. Zeldin, Dorothy T. Pei, Yan Gong, Dan Xu, Colman J. Hatton, Zhenghao Cui, Dipak Panigrahy, Matthew L. Edin, Zhongjie Fu, Ann Hellström, Jing Chen, Aimee Juan, Hannah H Bogardus, Lois E.H. Smith, Jean-Sébastien Joyal, Przemyslaw Sapieha, Christian G. Hurst, Fred B. Lih, Lucy P. Evans, Katherine Tian, Zhuo Shao
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 34(3)
Objective— Regulation of angiogenesis is critical for many diseases. Specifically, pathological retinal neovascularization, a major cause of blindness, is suppressed with dietary ω3-long-chain polyunsaturated fatty acids (ω3LCPUFAs) through antia
Autor:
J-S Joyal, Molly R. Seaward, Lois E.H. Smith, James D Akula, Timothy S. Kern, Tara L. Favazza, Roberta J. Dennison, J. Tang, Przemyslaw Sapieha, Jing Chen, Aimee M. Juan, Nathan M. Krah, Colman J. Hatton, Andreas Stahl
Publikováno v:
Nutrition & Diabetes
Objective: Diabetic retinopathy (DR) is associated with hyperglycemia-driven microvascular pathology and neuronal compromise in the retina. However, DR is also linked to dyslipidemia. As omega-3 (ω-3) polyunsaturated fatty acids (PUFAs) are protecti