Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Colm O'Huigin"'
Autor:
Keqiang Chen, John McCulloch, Rodrigo Das Neves, Gisele Rodrigues, Wang-Ting Hsieh, Wanghua Gong, Teizo Yoshimura, Jiaqiang Huang, Colm O’hUigin, Simone Difilippantonio, Matthew McCollum, Georgette Jones, Scott K. Durum, Giorgio Trinchieri, Ji Ming Wang
Publikováno v:
Gut Pathogens, Vol 15, Iss 1, Pp 1-18 (2023)
Abstract Background Formyl peptide receptor 2 (Fpr2) plays a crucial role in colon homeostasis and microbiota balance. Commensal E. coli is known to promote the regeneration of damaged colon epithelial cells. The aim of the study was to investigate t
Externí odkaz:
https://doaj.org/article/022dd32a81b448eeb260a4ff08e5723a
Autor:
Keqiang Chen, John McCulloch, Rodrigo Das Neves, Gisele Rodrigues, Wang-Ting Hsieh, Wanghua Gong, Teizo Yoshimura, Jiaqiang Huang, Colm O’hUigin, Simone Diflippantonio, Matthew McCollum, Georgette Jones, Scott K. Durum, Giorgio Trinchieri, Ji Ming Wang
Publikováno v:
Gut Pathogens, Vol 15, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/61534eb0d69f4c869111cfaa3684623c
Autor:
Weiwei Liang, Xinjian Peng, Qingqing Li, Pingzhang Wang, Ping Lv, Quansheng Song, Shaoping She, Shiyang Huang, Keqiang Chen, Wanghua Gong, Wuxing Yuan, Vishal Thovarai, Teizo Yoshimura, Colm O’huigin, Giorgio Trinchieri, Jiaqiang Huang, Shuye Lin, Xiaohong Yao, Xiuwu Bian, Wei Kong, Jianzhong Xi, Ji Ming Wang, Ying Wang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The cytokine like protein FAM3D (Fam3D in mice) is highly expressed in the digestive tract with unknown role in colon pathophysiology. Here, by using gene deficient mice, the authors show that Fam3D is critically involved in colon homeostasis, host d
Externí odkaz:
https://doaj.org/article/0ea1abe3c3234932b77c2016848d7dc0
Publikováno v:
Immunogenetics. 75:263-267
The leukocyte immunoglobulin–like receptor (LILR)B3 and LILRA6 genes encode homologous myeloid inhibitory and activating orphan receptors, respectively. Both genes exhibit a strikingly high level of polymorphism at the amino acid level and LILRA6 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83f7b58f13a7e19e41c6cd2a85880135
https://doi.org/10.1007/s00251-022-01286-1
https://doi.org/10.1007/s00251-022-01286-1
Autor:
John A. McCulloch, Jonathan H. Badger, Nikki Cannon, Richard R. Rodrigues, Michael Valencia, Jennifer J. Barb, Miriam R. Fernandes, Ascharya Balaji, Lisa Crowson, Colm O’hUigin, Amiran Dzutsev, Giorgio Trinchieri
Shotgun microbiome sequencing analysis presents several challenges to accurately and consistently depict sample composition and functional potential. Here we present a two-part framework – JAMS (Just a Microbiology System) – whereby with raw fast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02b863c63d44421d5f21bf7a0084fe64
https://doi.org/10.1101/2023.03.03.531026
https://doi.org/10.1101/2023.03.03.531026
Autor:
Amiran K. Dzutsev, Teizo Yoshimura, Keqiang Chen, Jiaqiang Huang, John McCulloch, Colm O'hUigin, Giorgio Trinchieri, Xiu-Wu Bian, Xiao-Hong Yao, Ji Ming Wang, Wanghua Gong
Publikováno v:
The Journal of Pathology
The cathelin‐related antimicrobial peptide CRAMP protects the mouse colon from inflammation, inflammation‐associated carcinogenesis, and disrupted microbiome balance, as shown in systemic Cnlp −/− mice (also known as Camp −/− mice). Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2573b17a276ea1e231c06e8c5023b71
https://doi.org/10.1002/path.5572
https://doi.org/10.1002/path.5572
Autor:
Qingqing Li, Vishal Thovarai, Ji Ming Wang, Shaoping She, Xiu-Wu Bian, Wanghua Gong, Ying Wang, Weiwei Liang, X. Peng, Wei Kong, Shiyang Huang, Ping Lv, Teizo Yoshimura, Wuxing Yuan, Keqiang Chen, Jianzhong Xi, Quansheng Song, Giorgio Trinchieri, Jiaqiang Huang, Xiao-Hong Yao, Shuye Lin, Pingzhang Wang, Colm O'hUigin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Nature Communications
The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (mouse Fam3D), is highly express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f306e6d0d3d05334ccd0be4bc1a5342d
https://doaj.org/article/0ea1abe3c3234932b77c2016848d7dc0
https://doaj.org/article/0ea1abe3c3234932b77c2016848d7dc0
Autor:
Effie W Petersdorf, Mary Carrington, Colm O'hUigin, Mats Bengtsson, Dianne De Santis, Valerie Dubois, Ted Gooley, Mary Horowitz, Katharine Hsu, J Alejandro Madrigal, Martin J Maiers, Mari Malkki, Caroline McKallor, Yasuo Morishima, Machteld Oudshoorn, Stephen R Spellman, Jean Villard, Phil Stevenson, Martin Maiers, Stephen Spellman, Jane Apperley, Peter Bardy, Ghislaine Bernard, Yves Bertrand, Adrian Bloor, Chiara Bonini, Stephane Buhler, Laura Bungener, Helen Campbell, Kristina Carlson, Ben Carpenter, Anne Cesbron, Christian Chabannon, Yves Chalandon, Jeremy Chapman, Réda Chebel, Patrice Chevallier, Gerda Choi, Matt Collin, Jan J Cornelissen, Charles Crawley, Lloyd D'Orsogna, Jean-Hugues Dalle, Eric Deconinck, Muriel DeMatteis, Mary Diviney, Anne Dormoy, Katia Gagne, Brenda Gibson, Maria Gilleece, David Gottlieb, John Gribben, Tayfun Güngör, Mike Haagenson, Cathie Hart, Rhonda Holdsworth, Ian Humphreys, Yoshihisa Kodera, Mickey Koh, Hélène Labussière-Wallet, Arjan C Lankester, Neubery Lardy, Sarah Lawson, Xavier Leleu, Stephen MacKinnon, Ram Malladi, Steven GE Marsh, Murray Martin, Neema P Mayor, I Grant McQuaker, Ellen Meijer, Satoko Morishima, Emmanouil Nikolousis, Kim Orchard, Jacob Passweg, Amit Patel, Katherine Patrick, Béatrice Pedron, Andy Peniket, Julia Perry, Eefke Petersen, Victoria Potter, Mike Potter, Rachel Protheroe, Nicole Raus, Carmen Ruiz de Elvira, Nigel Russell, Nicholaas PM Schaap, Urs Schanz, Harry Schouten, Roderick Skinner, John Snowden, Eric Spierings, Colin Steward, Eleni Tholouli, Alycia Thornton, Marcel Tilanus, Arnold van de Meer, Hendrik Veelkens, Paul Veys, Narelle Watson, Lyanne Weston, Keith Wilson, Marie Wilson, Robert Wynn, József Zsiros
Publikováno v:
The Lancet Haematology
The Lancet Haematology, Elsevier, 2021, 7 (1), pp.e50-e60. ⟨10.1016/s2352-3026(19)30208-x⟩
Petersdorf, E W, Carrington, M, O'hUigin, C, Bengtsson, M, De Santis, D, Dubois, V, Gooley, T, Horowitz, M, Hsu, K, Madrigal, J A, Maiers, M J, Malkki, M, McKallor, C, Morishima, Y, Oudshoorn, M, Spellman, S R, Villard, J, Stevenson, P & International Histocompatibility Working Group in Hematopoietic Cell Transplantation 2020, ' Role of HLA-B exon 1 in graft-versus-host disease after unrelated haemopoietic cell transplantation : a retrospective cohort study ', The Lancet Haematology, vol. 7, no. 1, pp. e50-e60 . https://doi.org/10.1016/S2352-3026(19)30208-X
The Lancet Haematology, 7(1), e50-e60. Lancet Publishing Group
The Lancet. Haematology, Vol. 7, No 1 (2020) pp. e50-e60
The Lancet Haematology, 7(1), E50-E60. ELSEVIER SCI LTD
The Lancet Haematology, 7(1), e50. Lancet Publishing Group
Lancet Haematol
The Lancet Haematology, Elsevier, 2021, 7 (1), pp.e50-e60. ⟨10.1016/s2352-3026(19)30208-x⟩
Petersdorf, E W, Carrington, M, O'hUigin, C, Bengtsson, M, De Santis, D, Dubois, V, Gooley, T, Horowitz, M, Hsu, K, Madrigal, J A, Maiers, M J, Malkki, M, McKallor, C, Morishima, Y, Oudshoorn, M, Spellman, S R, Villard, J, Stevenson, P & International Histocompatibility Working Group in Hematopoietic Cell Transplantation 2020, ' Role of HLA-B exon 1 in graft-versus-host disease after unrelated haemopoietic cell transplantation : a retrospective cohort study ', The Lancet Haematology, vol. 7, no. 1, pp. e50-e60 . https://doi.org/10.1016/S2352-3026(19)30208-X
The Lancet Haematology, 7(1), e50-e60. Lancet Publishing Group
The Lancet. Haematology, Vol. 7, No 1 (2020) pp. e50-e60
The Lancet Haematology, 7(1), E50-E60. ELSEVIER SCI LTD
The Lancet Haematology, 7(1), e50. Lancet Publishing Group
Lancet Haematol
Background: The success of unrelated haemopoietic cell transplantation (HCT) is limited by graft-versus-host disease (GVHD), which is the main post-transplantation challenge when HLA-matched donors are unavailable. A sequence dimorphism in exon 1 of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195a18e65915d7d3471d1ddf38d8b61a
https://www.hal.inserm.fr/inserm-03349714/document
https://www.hal.inserm.fr/inserm-03349714/document
Autor:
Arman A. Bashirova, Wanjing Zheng, Marjan Akdag, Danillo G. Augusto, Nicolas Vince, Krista L. Dong, Colm O’hUigin, Mary Carrington
Publikováno v:
Genes and Immunity
Genes and Immunity, 2021, 22 (7-8), pp.327-334. ⟨10.1038/s41435-021-00156-2⟩
Genes and Immunity, 2021, 22 (7-8), pp.327-334. ⟨10.1038/s41435-021-00156-2⟩
Human immunoglobulin G (IgG) molecules, IgG1, IgG2 and IgG3, exhibit substantial inter-individual variation in their constant heavy chain regions, as discovered by serological methods. This polymorphism is encoded by theIGHG1,IGHG2, andIGHG3genes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977d8d3918106b13399fb8cb9aa57b48
https://www.hal.inserm.fr/inserm-03627851
https://www.hal.inserm.fr/inserm-03627851
Autor:
Effie W. Petersdorf, Colm O'huigin
Publikováno v:
Human Immunology. 80:67-78
The MHC continues to have the most disease-associations compared to other regions of the human genome, even in the genome-wide association study (GWAS) and single nucleotide polymorphism (SNP) era. Analysis of non-coding variation and their impact on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798a8e8b56032dea6b75e2ba926f5cfb
https://doi.org/10.1016/j.humimm.2018.10.002
https://doi.org/10.1016/j.humimm.2018.10.002