Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer

Autor: Sarah Abou Alaiwi, Radhika A. Patel, Nicholas J. Dyson, Alba Font-Tello, Myles Brown, Wenzel M. Hackeng, Peter S. Nelson, Lisha G. Brown, Neel Shah, Himisha Beltran, Alok K. Tewari, Sylvan C. Baca, Michael C. Haffner, Paloma Cejas, Yingtian Xie, Benjamin J. Drapkin, Xintao Qiu, Sudeepa Syamala, Lodewijk A.A. Brosens, Colm Morrisey, Eva Corey, Holly M. Nguyen, Alessandra Dall’Agnese, Mark Pomerantz, Ilsa Coleman, Koen M.A. Dreijerink, Matthew L. Freedman, Leigh Ellis, Eliezer M. Van Allen, X. Shirley Liu, Francesca Khani, Klothilda Lim, Anna F. Farago, James A. DeCaprio, Ji-Heui Seo, Henry W. Long, Jett Crowdis, Joaquim Bellmunt

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Cejas, P, Xie, Y, Font-Tello, A, Lim, K, Syamala, S, Qiu, X, Tewari, A K, Shah, N, Nguyen, H M, Patel, R A, Brown, L, Coleman, I, Hackeng, W M, Brosens, L, Dreijerink, K M A, Ellis, L, Alaiwi, S A, Seo, J-H, Baca, S, Beltran, H, Khani, F, Pomerantz, M, Dall’Agnese, A, Crowdis, J, van Allen, E M, Bellmunt, J, Morrisey, C, Nelson, P S, DeCaprio, J, Farago, A, Dyson, N, Drapkin, B, Liu, X S, Freedman, M, Haffner, M C, Corey, E, Brown, M & Long, H W 2021, ' Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer ', Nature Communications, vol. 12, no. 1, 5775 . https://doi.org/10.1038/s41467-021-26042-z
Nature Communications, 12
Nature Communications, 12, 1
Nature Communications
Nature Communications, 12(1):5775. Nature Publishing Group

Neuroendocrine carcinomas (NEC) are tumors expressing markers of neuronal differentiation that can arise at different anatomic sites but have strong histological and clinical similarities. Here we report the chromatin landscapes of a range of human N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad439e770fa533c12d29847bffe68ad2
http://www.scopus.com/inward/record.url?scp=85116354103&partnerID=8YFLogxK

Abstract 5159: Identification of ARv567es expression profile in the prostate cancer clinical samples with a newly developed antibody

Autor: Shihua Sun, Colm Morrisey, Eva Corey, Aihua Li, Stephen R. Plymate, Gang Liu, Cynthia C. Sprenger, Scott M. Dehm

Publikováno v: Cancer Research. 75:5159-5159

Background: Androgen receptor splice variants (AR-Vs) have emerged as an important diagnostic biomarker and potential therapeutic oncotarget in castration-resistant prostate cancer. Extensive RNA sequencing of a large cohort of metastases from men tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6202f0a333756b3a91eb3a10b0a53df3
https://doi.org/10.1158/1538-7445.am2015-5159